1. Preamble
2. Introduction.
3. Epidemiology and risk factors
3.1 Epidemiology
3.2 Risk factors
3.3 Prognosis
4.General aspects
4.1.Diagnostic approach
4.2 Treatment approach
5.Antithrombotic drugs in PADs
5.1 Antithrombotic treatment in carotid artery disease
5.2 Antithrombotic therapy in lower extremity artery disease.
5.3 Antithrombotic therapy in lower extremity artery disease patients requiring long-term oral anticoagulant
5.4 Antithrombotic therapy after endovascular therapy in other territories
6. Extracranial carotid and vertebral artery disease
6.1 Carotid artery disease
6.2 Vertebral artery disease
7.Upper extremity artery disease.
7.4Diagnosticmethods
7.5 Treatment
8.Mesenteric artery disease
8.1 Acute mesenteric ischaemia
8.2 Chronicmesenteric artery disease
9.Renal artery disease
9.1 Introduction
9.2 Clinical presentation
9.3 Natural history
9.4 Diagnostic strategy
9.5 Prognosis
9.6 Treatment
10. Lower extremity artery disease
10.1. Clinical presentation and natural history
10.2 Diagnostic tests
10.3 Medical treatment
10.4 Revascularization options: general aspects
10.5 Management of intermittent claudication
10.6 Chronic limb-threatening ischaemia
10.7Acute limb ischaemia
10.8 Blue toe syndrome
11. Multisite artery disease
11.1 Multisite artery disease: epidemiology and impact prognosis.
11.2 Screening for and management of multisite artery disease
12. Cardiac conditions in peripheral arterial diseases
12.1 Introduction
12.2 Heart failure and peripheral arterial diseases
12.3 Peripheral arterial diseases and atrial fibrillation
12.4 Peripheral arterial diseases and valvular heart disease
12.5 Peripheral arterial diseases and vascular access site for cardiac interventions
13. Gaps in evidence
14. To do and not to do messages from the Guidelines
15.Web addenda and companion document
16. Appendix
17. References