- CTACC (Clinical Trials in Acute Cardiovascular Care) - Chaired by Prof. Holger Thiele (DE), this group was created in March 2019. It develops ideas for large-scale clinical projects/trials in acute cardiovascular care to close the current existing gaps in evidence.
- Biomarkers – Focusing on the proper clinical application of cardiac biomarkers. This group was established by Kristian Thygesen (DK) in 2005 within the former working group on Acute Cardiac Care and is now chaired by Christian Mueller (SW).
- Acute Heart Failure - Highlighting unmet needs and areas of uncertainty in the care of acute HF patients.
Created in May 2013, this group is under the leadership of Josep Masip (ES). - Quality Of Care (QoC) - Comprising experts focusing on QoC within acute cardiac care situations, this study group is interdisciplinary and international, under the leadership of Prof. Francois Schiele (FR).
- Spontaneous Coronary Artery Dissection (SCAD) - Working to improve awareness and understanding of this rare coronary artery disease, this group was created in January 2016 under the leadership of Dr. David Adlam (UK) and Prof. Christiaan Vrints (BE).
- EXPERT-PE on Acute Pulmonary Embolism (Acute PE) - An ACVC study group created in 2023, chaired by Prof. Erik Klok and Prof. Stavros Konstantinides.