From hemodynamics to the 2025 guidelines: three-part series on the future of post-cardiac arrest care.

Featuring insights from renowned specialists, this project, produced in collaboration with ESICM Next and the Young European Resuscitation Council (ERC), highlights the clinical best practices and research gaps that will define resuscitation science in the coming years

Episode 1 focuses on:

  • The critical decisions that shape outcomes after cardiac arrest, from understanding post-resuscitation hemodynamic instability to applying targeted blood pressure, fluid, and vasoactive strategies,
  • Exploring when and how mechanical circulatory support can be used after out-of-hospital cardiac arrest,
  • The goal of integrating physiology, technology, and teamwork into modern post–cardiac arrest care.

Episode 2, with ESICM Next focuses on: 

  • Coronary angiography after OHCA without STEMI: aligning contemporary trial evidence with individualised clinical decision‑making.
  • Unstable patients and eCPR: exploring invasive strategies in high‑risk phenotypes excluded from randomised trials.
  • Neuroprognostication after cardiac arrest: applying a multimodal, guideline‑based approach in the face of discordant findings.
  • Withdrawal of life‑sustaining treatment: optimising timing and decision‑making to avoid premature prognostic conclusions.

Episode 3, with the young ERC focuses on: 

  • Precision physiology: Moving beyond "one-size-fits-all" targets for blood pressure and temperature to more individualised patient care.
  • The 2025 guideline shift: Understanding the specific updates in temperature management (TTM) and hemodynamic stability.
  • Evidence-based prognostication: The evolving role of biomarkers in predicting neurological outcomes without premature withdrawal of life-sustaining treatment.
  • The research horizon: Identifying the specific clinical questions that remain unanswered in the current literature.