Our mission is to become a worldwide reference for education in the field for all professionals involved in the process to disseminate knowledge & skills of Acute Cardiovascular Care.
Our mission is to promote excellence in clinical diagnosis, research, technical development, and education in cardiovascular imaging in Europe.
Our mission is to promote excellence in research, practice, education and policy in cardiovascular health, primary and secondary prevention.
Our mission is to reduce the burden of cardiovascular disease through percutaneous cardiovascular interventions.
Improving the quality of life and reducing sudden cardiac death by limiting the impact of heart rhythm disturbances.
Our mission is to improve quality of life and longevity, through better prevention, diagnosis and treatment of heart failure, including the establishment of networks for its management, education and research.
The ESC Working Groups' goal is to stimulate and disseminate scientific knowledge in different fields of cardiology.
The ESC Councils' goal is to share knowledge among medical professionals practising in specific cardiology domains.
OUR MISSION: TO REDUCE THE BURDEN OF CARDIOVASCULAR DISEASE
Only few preliminary experimental studies demonstrated the feasibility of adenosine stress CT myocardial perfusionimaging to calculate the absolute MBF, thereby providing information whether a coronary stenosis is flow limiting.
In seven pigs, a coronary flow probe and an adjustable hydraulic occluder were placed around the left anterior descending coronary artery to monitor the distal coronary artery blood flow (CBF) while several degrees of coronaryflow reduction were induced. CT perfusion (CT-MBF) was acquired during adenosine stress with no CBF reduction,an intermediate (15–39%) and a severe (40–95%) CBF reduction. Reference standards were CBF and fractional flowreserve measurements (FFR). FFR was simultaneously derived from distal coronary artery pressure and aortic pressure measurements.
CT-MBF decreased progressively with increasing CBF reduction severity from 2.68 (2.31–2.81) mL/g/min (normal CBF) to 1.96 (1.83–2.33) mL/g/min (intermediate CBF-reduction) and to 1.55 (1.14–2.06) mL/g/min (severe CBF-reduction) (both P <0.001). We observed very good correlations between CT-MBF and CBF (r=0.85, P<0.001) and CT-MBF and FFR (r=0.85, P<0.001).
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