Recommended Reading on Cardiovascular Regenerative and Reparative Medicine

ESC Working Group on Cardiovascular Regenerative and Reparative Medicine

In PLN-R14del mice, SR structure restoration, rather than calcium cycling, is the dominant effector of PLN-ASO treatment

Cardiovascular Research
4 Sep 2025

An activator of phosphatidylinositol 3-kinase alpha restores cardioprotection from ischaemia/reperfusion injury in mice with coronary atherosclerosis or insulin resistance

Cardiovascular Research
13 Jun 2025

Single-cell epigenomic and transcriptomic analysis unveils the pivotal role of GATA5/ISL1<sup>+</sup> fibroblasts in cardiac repair post-myocardial infarction

Cardiovascular Research
3 Jun 2025

Empagliflozin enhances metabolic efficiency and improves left ventricular hypertrophy in a hypertrophic cardiomyopathy mouse model

European Heart Journal
21 May 2025

Integrated proteomics identifies troponin I isoform switch as a regulator of a sarcomere-metabolism axis during cardiac regeneration

Cardiovascular Research
18 Apr 2025

Pre-ischaemic empagliflozin treatment attenuates blood–brain barrier disruption via β-catenin mediated protection of cerebral endothelial cells

Cardiovascular Research
2 Apr 2025

Cardiomyocyte SORBS2 expression increases in heart failure and regulates integrin interactions and extracellular matrix composition

Cardiovascular Research
17 Feb 2025

<em>SCN10A-short</em> gene therapy to restore conduction and protect against malignant cardiac arrhythmias

European Heart Journal
20 Feb 2025

SGLT2 expression in human vasculature and heart correlates with low-grade inflammation and causes eNOS-NO/ROS imbalance

Cardiovascular Research
31 Dec 2024

Extracellular vesicle-mediated VEGF-A mRNA delivery rescues ischaemic injury with low immunogenicity

European Heart Journal
20 Jan 2025

Clinical trials in-a-dish for cardiovascular medicine

European Heart Journal
13 Sep 2024

Hypoxia-responsive zinc finger E-box-binding homeobox 2 (ZEB2) regulates a network of calcium-handling genes in the injured heart

Cardiovascular Research
23 Sep 2024

RNA and the emerging potential of bio-inspired molecules in cardiovascular disease therapies

European Heart Journal
13 Jun 2024

Injury minimization after myocardial infarction: focus on extracellular vesicles

European Heart Journal
15 Feb 2024

Non-coding RNA yREX3 from human extracellular vesicles exerts macrophage-mediated cardioprotection via a novel gene-methylating mechanism

European Heart Journal
12 Jun 2024

Gene therapy encoding cell cycle factors to treat chronic ischemic heart failure in rats

Cardiovascular Research
4 Jan 2024

Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles

Cardiovascular Research
24 Mar 2022

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

Cardiovascular Research
6 Jan 2022

Novel antisense therapy targeting microRNA-132 in patients with heart failure: results of a first-in-human Phase 1b randomized, double-blind, placebo-controlled study

European Heart Journal
11 Nov 2020

FGF10 promotes cardiac repair through a dual cellular mechanism increasing cardiomyocyte renewal and inhibiting fibrosis<sup> </sup>

Cardiovascular Research
10 Nov 2021

ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure

Cardiovascular Research
17 Jan 2019