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Perfusion SPECT and the impact of renal function on cardiac death

Non-invasive Imaging: Nuclear Cardiology


 

Comment on the above paper

Chronic kidney disease (CKD) is an important risk factor for cardiovascular outcome.  In the present study, Hakeem et al studied a large cohort of patients (n=1652) with suspected CAD who underwent stress MPS and an evaluation of kidney function (by means of calculation of eGFR).  At baseline 36% had CKD defined as an eGFR < 60 ml/min/1.73m².  After a mean follow-up op 2 years both renal function and MPS showed incremental predictive power for cardiac death prediction over baseline risk factors and left ventricular dysfunction.  Importantly, patients with CKD had a relatively less benign prognosis that those without CKD, even in the presence of a normal scan.

References


  1. Hakeem A, Bhatti S, Dillie K et al.   H, Engblom E, Naum A et al.  Predictive value of myocardial perfusion SPECT and the impact of renal function on cardiac death.  Circulation 2008;118:2540-2549.
The content of this article reflects the personal opinion of the author/s and is not necessarily the official position of the European Society of Cardiology.