Atrial fibrillation is considered the most common arrhythmia and in the context of an aging population, its prevalence is expected to increase. On the other hand, early onset atrial fibrillation may be the first manifestation of an inherited cardiac condition. Atrial fibrillation is the most prevalent sustained arrhythmia in cardiomyopathies and it is also a frequent comorbidity in channelopathies, such as Brugada syndrome, long QT syndrome or catecholaminergic polymorphic ventricular tachycardia.

In these cases, affected individuals have an extremely different prognosis and clinical course. Hence, genetic testing in individuals with early-onset atrial fibrillation becomes relevant, as it may facilitate the diagnosis of an underlying inherited cardiac condition.

This volume explores the current available data supporting the role of genetic testing, while acknowledging the gaps in evidence and challenges clinicians might face.

With the contribution of Prof. Elijah Behr (City-St. George’s University of London, UK) we aim to present clinicians with the tools and data which will help them navigate the following questions: Who should be tested? Which test to use? When is it appropriate to use it?