Recommended Reading on Development, Anatomy & Pathology

Articles from non-ESC journals

• 01/10/2025
  • MEF2C controls segment-specific gene regulatory networks that direct heart tube morphogenesis

• 01/10/2025
  • Endocardial primary cilia and blood flow regulate EndoMT during endocardial cushion development

• 01/10/2025
  • Transcriptional regulation in heart development, disease and regeneration: reassessing the fetal gene hypothesis

• 01/08/2025
  • Tbx1 stabilizes differentiation of the cardiopharyngeal mesoderm and drives morphogenesis in the pharyngeal apparatus

• 01/08/2025
  • MYL4 Identifies Intramural Anatomy of Purkinje Fibers in Human Hearts

• 01/06/2025
  • GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis

• 01/06/2025
  • Border-zone cardiomyocytes and macrophages regulate extracellular matrix remodeling to promote cardiomyocyte protrusion during cardiac regeneration

• 01/06/2025
  • Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis

• 01/06/2025
  • Cardiac repair using regenerating neonatal heart tissue-derived extracellular vesicles

• 21/04/2025
  • Multi-modal refinement of the human heart atlas during the first gestational trimester

• 21/04/2025
  • Tunneling nanotube–like structures regulate distant cellular interactions during heart formation

• 21/04/2025
  • Cold and hot fibrosis define clinically distinct cardiac pathologies

• 01/02/2025
  • Direct specification of lymphatic endothelium from mesenchymal progenitors

• 01/02/2025
  • Participation of ventricular trabeculae in neonatal cardiac regeneration leads to ectopic recruitment of Purkinje-like cells

• 01/02/2025
  • Mesodermal fibronectin controls cell shape, polarity, and mechanotransduction in the second heart field during cardiac outflow tract development

• 01/12/2024
  • Deletion of ASPP1 in myofibroblasts alleviates myocardial fibrosis by reducing p53 degradation

• 01/12/2024
  • Intramyocardial sprouting tip cells specify coronary arterialization

• 01/12/2024
  • Modeling the atrioventricular conduction axis using human pluripotent stem cell-derived cardiac assembloids

• 01/06/2024
  • CHD4 and SMYD1 repress common transcriptional programs in the developing heart

• 01/06/2024
  • Buffering Mechanism in Aortic Arch Artery Formation and Congenital Heart Disease

• 01/06/2024
  • Multi-chamber cardioids unravel human heart development and cardiac defects

• 01/04/2024
  • ING4 and ING5 are essential for histone H3 lysine 14 acetylation and epicardial cell lineage development

• 01/04/2024
  • Extracellular matrix disorganization caused by ADAMTS16 deficiency leads to bicuspid aortic valve with raphe formation

• 01/04/2024
  • Versican promotes cardiomyocyte proliferation and cardiac repair

• 01/02/2024
  • Identification of Greb1l as a genetic determinant of crisscross heart in mice showing torsion of the heart tube by shortage of progenitor cells.

• 01/02/2024
  • A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization

• 01/02/2024
  • HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function

• 01/12/2023
  • Fibroblasts in heart scar tissue directly regulate cardiac excitability and arrhythmogenesis

• 01/12/2023
  • Combined treatment of human induced pluripotent stem cell–derived cardiomyocytes and endothelial cells regenerate the infarcted heart in mice and non-human primates

• 01/12/2023
  • Systemic hypoxemia induces cardiomyocyte Hypertrophy and right ventricular specific Induction of proliferation

• 01/10/2023
  • CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression

• 01/10/2023
  • Single-cell analysis of human fetal epicardium reveals its cellular composition and identifies CRIP1 as a modulator of EMT

• 01/10/2023
  • POLR1A variants underlie phenotypic heterogeneity in craniofacial, neural, and cardiac anomalies

• 20/09/2023
  • POLR1A variants underlie phenotypic heterogeneity in craniofacial, neural, and cardiac anomalies

• 20/09/2023
  • CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression

• 20/09/2023
  • Single-cell analysis of human fetal epicardium reveals its cellular composition and identifies CRIP1 as a modulator of EMT

• 08/08/2023
  • Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration.

• 08/08/2023
  • Origin of congenital coronary arterio-ventricular fistulae from anomalous epicardial and myocardial development

• 08/08/2023
  • SERCA2 phosphorylation at serine 663 is a key regulator of Ca2+ homeostasis in heart diseases

• 01/04/2023
  • Graded mesoderm assembly governs cell fate and morphogenesis of the early mammalian heart

• 01/04/2023
  • The heart field transcriptional landscape at single-cell resolution

• 01/04/2023
  • Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice

• 01/02/2023
  • Loss of nuclear envelope integrity and increased oxidant production cause DNA damage in adult hearts deficient in PKP2

• 01/02/2023
  • Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages

• 11/03/2022
  • A pictorial account of the human embryonic heart between 3.5 and 8 weeks of development

• 08/03/2022
  • Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch

• 17/02/2022
  • Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy

• 07/01/2022
  • Extension of endocardium-derived vessels generate coronary arteries in neonates

• 22/10/2021
  • Cq values do not reflect nucleic acid quantity in biological samples

• 15/10/2021
  • Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation

• 15/10/2021
  • Bioelectric signaling and the control of cardiac cell identity in response to mechanical forces

• 05/10/2021
  • Reducing soft‐tissue shrinkage artefacts caused by staining with Lugol’s solution

• 26/09/2021
  • Variably methylated retrotransposons are refractory to a range of environmental perturbations

• 06/09/2021
  • Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance

• 18/08/2021
  • A convergent molecular network underlying autism and congenital heart disease

• 02/08/2021
  • Variant Intronic Enhancer Controls SCN10A-Short Expression and Heart Conduction

• 02/08/2021
  • Ventricular, atrial, and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak

• 02/08/2021
  • Maternal iron deficiency perturbs embryonic cardiovascular development in mice

• 29/05/2021
  • Use and Misuse of Cq in qPCR Data Analysis and Reporting

• 30/04/2021
  • Innervation and Neuronal Control of the Mammalian Sinoatrial Node a Comprehensive Atlas

• 17/03/2021
  • Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis

• 08/03/2021
  • Sex-Specific Control of Human Heart Maturation by the Progesterone Receptor

• 15/02/2021
  • The Leiden Convention coronary coding system: translation from the surgical to the universal view

• 04/02/2021
  • Capturing Cardiogenesis in Gastruloids

• 03/02/2021
  • Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart

• 07/01/2021
  • Characterization of a common progenitor pool of the epicardium and myocardium

• 01/01/2021
  • Genetic lineage tracing reveals poor angiogenic potential of cardiac endothelial cells

• 14/12/2020
  • Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease

• 13/11/2020
  • A human cell atlas of fetal gene expression

• 31/10/2020
  • Leaders in Cardiovascular Research: A special issue dedicated to Professor Robert Anderson

• 25/09/2020
  • Single-Cell RNA Sequencing Analysis Reveals a Crucial Role for CTHRC1 (Collagen Triple Helix Repeat Containing 1) Cardiac Fibroblasts After Myocardial Infarction

• 01/09/2020
  • Delta-like ligand 4-mediated Notch signaling controls proliferation of second heart field progenitor cells by regulating Fgf8 expression

• 01/08/2020
  • Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation

• 10/05/2020
  • Expression of Hey2 Transcription Factor in the Early Embryonic Ventricles Is Controlled Through a Distal Enhancer by Tbx20 and Gata Transcription Factors

• 01/05/2020
  • Pulmonary ductal coarctation and left pulmonary artery interruption; pathology and role of neural crest and second heart field during development

• 03/04/2020
  • Piezo1 Is Required for Outflow Tract and Aortic Valve Development

• 01/04/2020
  • Platelet-derived Growth factor-AB Improves Scar Mechanics and Vascularity After Myocardial Infarction

• 02/03/2020
  • Evidence from Family Studies for Autoimmunity in Arrhythmogenic Right Ventricular Cardiomyopathy: Associations of Circulating Anti-Heart and Anti-Intercalated Disk Autoantibodies with Disease Severity and Family History

• 03/02/2020
  • Congenitally corrected transposition of the great arteries: is it really a transposition? An anatomical study of the right ventricular septal surface

• 03/02/2020
  • Cardiopharyngeal mesoderm origins of musculoskeletal and connective tissues in the mammalian pharynx

• 06/01/2020
  • Multiple mycotic aneurysms of the aortic root after aortic valve replacement

• 04/12/2019
  • Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade

• 31/10/2019
  • POPDC proteins and cardiac function

• 10/09/2019
  • Mitral Valve Prolapse, Ventricular Arrhythmias, and Sudden Death

• 15/07/2019
  • Tbx1 regulates extracellular matrix-cell interactions in the second heart field

• 09/07/2019
  • Standardised imaging pipeline for phenotyping mouse laterality defects and associated heart malformations, at multiple scales and multiple stages

• 21/06/2019
  • A single-cell transcriptional roadmap for cardiopharyngeal fate diversification

• 17/06/2019
  • Cilia, mitochondria, and cardiac development

• 01/05/2019
  • Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis

• 26/04/2019
  • Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis

• 04/04/2019
  • Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis

• 20/02/201
  • Gene-environment interaction impacts on heart development and embryo survival

• 20/02/2019
  • Gene-environment interaction impacts on heart development and embryo survival

• 15/02/2019
  • Whole Exome Sequencing Reveals the Major Genetic Contributors to Nonsyndromic Tetralogy of Fallot

• 10/02/2019
  • Anomalous aortic origin of coronary arteries: Early results on clinical management from an international multicenter study

• 04/02/2019
  • A new anatomic approach of the ventricular septal defect in the interruption of the aortic arch

• 04/02/2019
  • A new anatomic approach of the ventricular septal defect in the interruption of the aortic arch

• 20/01/2019
  • Cell-based therapies for the treatment of myocardial infarction: lessons from cardiac regeneration and repair mechanisms in non-human vertebrates

• 26/12/2018
  • Profiling proliferative cells and their progeny in damaged murine hearts

• 22/11/2018
  • Left-right asymmetry in heart development and disease: forming the right loop

• 01/11/2018
  • T-box genes and retinoic acid signaling regulate the segregation of arterial and venous pole progenitor cells in the murine second heart field

• 31/10/2018
  • Endomyocardial fibrosis and myocardial infarction leading to diastolic and systolic dysfunction requiring transplantation

• 25/07/2018
  • Novel ALPK3 mutation in a Tunisian patient with pediatric cardiomyopathy and facio-thoraco-skeletal features

• 14/07/2018
  • Planar cell polarity in organ formation

• 29/06/2018
  • A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice

• 31/05/2018
  • Bmp2 and Notch cooperate to pattern the embryonic endocardium

• 05/01/2018
  • Epithelial Properties of the Second Heart Field