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Recommended Reading on Cardiovascular Regenerative and Reparative Medicine

ESC Working Group on Cardiovascular Regenerative and Reparative Medicine

In PLN-R14del mice, SR structure restoration, rather than calcium cycling, is the dominant effector of PLN-ASO treatment

Cardiovascular Research
4 Sep 2025

An activator of phosphatidylinositol 3-kinase alpha restores cardioprotection from ischaemia/reperfusion injury in mice with coronary atherosclerosis or insulin resistance

Cardiovascular Research
13 Jun 2025

Single-cell epigenomic and transcriptomic analysis unveils the pivotal role of GATA5/ISL1<sup>+</sup> fibroblasts in cardiac repair post-myocardial infarction

Cardiovascular Research
3 Jun 2025

Empagliflozin enhances metabolic efficiency and improves left ventricular hypertrophy in a hypertrophic cardiomyopathy mouse model

European Heart Journal
21 May 2025

Integrated proteomics identifies troponin I isoform switch as a regulator of a sarcomere-metabolism axis during cardiac regeneration

Cardiovascular Research
18 Apr 2025

Pre-ischaemic empagliflozin treatment attenuates blood–brain barrier disruption via β-catenin mediated protection of cerebral endothelial cells

Cardiovascular Research
2 Apr 2025

<em>SCN10A-short</em> gene therapy to restore conduction and protect against malignant cardiac arrhythmias

European Heart Journal
20 Feb 2025

Cardiomyocyte SORBS2 expression increases in heart failure and regulates integrin interactions and extracellular matrix composition

Cardiovascular Research
17 Feb 2025

Extracellular vesicle-mediated VEGF-A mRNA delivery rescues ischaemic injury with low immunogenicity

European Heart Journal
20 Jan 2025

SGLT2 expression in human vasculature and heart correlates with low-grade inflammation and causes eNOS-NO/ROS imbalance

Cardiovascular Research
31 Dec 2024

Hypoxia-responsive zinc finger E-box-binding homeobox 2 (ZEB2) regulates a network of calcium-handling genes in the injured heart

Cardiovascular Research
23 Sep 2024

Clinical trials in-a-dish for cardiovascular medicine

European Heart Journal
13 Sep 2024

RNA and the emerging potential of bio-inspired molecules in cardiovascular disease therapies

European Heart Journal
13 Jun 2024

Non-coding RNA yREX3 from human extracellular vesicles exerts macrophage-mediated cardioprotection via a novel gene-methylating mechanism

European Heart Journal
12 Jun 2024

Injury minimization after myocardial infarction: focus on extracellular vesicles

European Heart Journal
15 Feb 2024

Gene therapy encoding cell cycle factors to treat chronic ischemic heart failure in rats

Cardiovascular Research
4 Jan 2024

Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles

Cardiovascular Research
24 Mar 2022

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

Cardiovascular Research
6 Jan 2022

FGF10 promotes cardiac repair through a dual cellular mechanism increasing cardiomyocyte renewal and inhibiting fibrosis<sup> </sup>

Cardiovascular Research
10 Nov 2021

Novel antisense therapy targeting microRNA-132 in patients with heart failure: results of a first-in-human Phase 1b randomized, double-blind, placebo-controlled study

European Heart Journal
11 Nov 2020

ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure

Cardiovascular Research
17 Jan 2019