Atherosclerosis and Vascular Biology

Sirtuin-1 directly binds and deacetylates hepatic PCSK9 thereby promoting the inhibition of LDL receptor degradation

Cardiovascular Research

14 Jul 2025

Endothelial plasticity in atrial fibrosis by integrating single-cell sequencing and genetic lineage tracing

European Heart Journal

8 Jul 2025

Colchicine for secondary prevention of vascular events: a meta-analysis of trials

European Heart Journal

2 May 2025

Long-term trials of colchicine for secondary prevention of vascular events: a meta-analysis

European Heart Journal

2 May 2025

Targeting the pyruvate dehydrogenase kinase/pyruvate dehydrogenase axis modulates neutrophil and smooth muscle cell pathological responses and prevents abdominal aortic aneurysm formation

Cardiovascular Research

4 Mar 2025

Distinct inflammatory pathways shape atherosclerosis in different vascular beds

European Heart Journal

27 Feb 2025

Cardioprotection exerted by intravenous statin at index myocardial infarction event attenuates cardiac damage upon recurrent infarction

Cardiovascular Research

3 Jan 2025

SGLT2 expression in human vasculature and heart correlates with low-grade inflammation and causes eNOS-NO/ROS imbalance

Cardiovascular Research

31 Dec 2024

Atheroma transcriptomics identifies ARNTL as a smooth muscle cell regulator and with clinical and genetic data improves risk stratification

European Heart Journal

18 Nov 2024

Plasma proteome and incident myocardial infarction: sex-specific differences

European Heart Journal

14 Oct 2024

Systemic inflammation and health outcomes in patients receiving treatment for atherosclerotic cardiovascular disease

European Heart Journal

30 Aug 2024

Glucagon-like peptide-1 increases heart rate by a direct action on the sinus node

Cardiovascular Research

4 Jun 2024

Atherosclerosis in ancient mummified humans: the global HORUS study

European Heart Journal

28 May 2024

Endothelial nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome regulation in atherosclerosis

Cardiovascular Research

16 Apr 2024

Understanding and controlling the increasing burden of cardiovascular diseases in Africa

Cardiovascular Research

5 Mar 2024

Inhibition of a novel Dickkopf-1-LDL receptor–related proteins 5 and 6 axis prevents diabetic cardiomyopathy in mice

European Heart Journal

28 Dec 2023

Myocardial infarction drives trained immunity of monocytes, accelerating atherosclerosis

European Heart Journal

12 Dec 2023

4-Hydroxynonenal impairs miRNA maturation in heart failure via Dicer post-translational modification

European Heart Journal

7 Nov 2023

Deletion of adipocyte NOS3 potentiates high-fat diet-induced hypertension and vascular remodelling via chemerin

Cardiovascular Research

28 Oct 2023

Circulating GDF11 exacerbates myocardial injury in mice and associates with increased infarct size in humans

Cardiovascular Research

23 Sep 2023

Cardiomyocyte and endothelial cells play distinct roles in the tumour necrosis factor (TNF)-dependent atrial responses and increased atrial fibrillation vulnerability induced by endurance exercise training in mice

Cardiovascular Research

15 Sep 2023

Women, lipids, and atherosclerotic cardiovascular disease: a call to action from the European Atherosclerosis Society

European Heart Journal

23 Aug 2023

Chronic SIRT1 supplementation in diabetic mice improves endothelial function by suppressing oxidative stress

Cardiovascular Research

4 Jul 2023

Single-cell profiling reveals age-associated immunity in atherosclerosis

Cardiovascular Research

30 Jun 2023

Culprit plaque morphology determines inflammatory risk and clinical outcomes in acute coronary syndrome

European Heart Journal

29 Jun 2023

Thrombin-activated interleukin-1α drives atherogenesis, but also promotes vascular smooth muscle cell proliferation and collagen production

Cardiovascular Research

13 Jun 2023

Cationic proteins from eosinophils bind bone morphogenetic protein receptors promoting vascular calcification and atherogenesis

European Heart Journal

3 Jun 2023

Air pollution and plaque healing in acute coronary syndromes

European Heart Journal

2 Jun 2023

NLRP3 inflammasome and interleukin-1 contributions to COVID-19-associated coagulopathy and immunothrombosis

Cardiovascular Research

30 May 2023

Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk

Cardiovascular Research

2 Mar 2023

Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity

European Heart Journal

20 Jan 2023

JCAD promotes arterial thrombosis through PI3K/Akt modulation: a translational study

European Heart Journal

5 Dec 2022

Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture–prone atherosclerotic plaques

European Heart Journal

9 Feb 2022

Dynamic changes in chromatin accessibility are associated with the atherogenic transitioning of vascular smooth muscle cells

Cardiovascular Research

24 Nov 2021

Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis

European Heart Journal

19 Jul 2021

Neutralization of S100A4 induces stabilization of atherosclerotic plaques: role of smooth muscle cells

Cardiovascular Research

2 Nov 2020

Adoptive transfer of CX3CR1 transduced-T regulatory cells improves homing to the atherosclerotic plaques and dampens atherosclerosis progression

Cardiovascular Research

15 Sep 2020

Sirtuin 5 promotes arterial thrombosis by blunting the fibrinolytic system

Cardiovascular Research

15 Sep 2020

Gut microbiota and myocardial infarction

European Heart Journal

16 Apr 2020

A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography

European Heart Journal

3 Sep 2019

High-density lipoprotein remodelled in hypercholesterolaemic blood induce epigenetically driven down-regulation of endothelial HIF-1α expression in a preclinical animal model

Cardiovascular Research

30 Aug 2019

Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling

Cardiovascular Research

1 Aug 2019

Identifying the anti-inflammatory response to lipid lowering therapy: a position paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology

Cardiovascular Research

6 Dec 2018

Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death

European Heart Journal

17 Nov 2018

Focus on echovascular imaging assessment of arterial disease: complement to the ESC guidelines (PARTIM 1) in collaboration with the Working Group on Aorta and Peripheral Vascular Diseases

European Heart Journal - Cardiovascular Imaging

18 Sep 2018

PCSK9 deficiency reduces insulin secretion and promotes glucose intolerance: the role of the low-density lipoprotein receptor

European Heart Journal

2 Jul 2018

Recommended Reading on Atherosclerosis and Vascular Biology

ESC Working Group on Atherosclerosis and Vascular Biology

Sirtuin-1 directly binds and deacetylates hepatic PCSK9 thereby promoting the inhibition of LDL receptor degradation

Endothelial plasticity in atrial fibrosis by integrating single-cell sequencing and genetic lineage tracing

Colchicine for secondary prevention of vascular events: a meta-analysis of trials

Long-term trials of colchicine for secondary prevention of vascular events: a meta-analysis

Targeting the pyruvate dehydrogenase kinase/pyruvate dehydrogenase axis modulates neutrophil and smooth muscle cell pathological responses and prevents abdominal aortic aneurysm formation

Distinct inflammatory pathways shape atherosclerosis in different vascular beds

Cardioprotection exerted by intravenous statin at index myocardial infarction event attenuates cardiac damage upon recurrent infarction

SGLT2 expression in human vasculature and heart correlates with low-grade inflammation and causes eNOS-NO/ROS imbalance

Atheroma transcriptomics identifies ARNTL as a smooth muscle cell regulator and with clinical and genetic data improves risk stratification

Plasma proteome and incident myocardial infarction: sex-specific differences

Systemic inflammation and health outcomes in patients receiving treatment for atherosclerotic cardiovascular disease

Glucagon-like peptide-1 increases heart rate by a direct action on the sinus node

Atherosclerosis in ancient mummified humans: the global HORUS study

Endothelial nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome regulation in atherosclerosis

Understanding and controlling the increasing burden of cardiovascular diseases in Africa

Inhibition of a novel Dickkopf-1-LDL receptor–related proteins 5 and 6 axis prevents diabetic cardiomyopathy in mice

Myocardial infarction drives trained immunity of monocytes, accelerating atherosclerosis

4-Hydroxynonenal impairs miRNA maturation in heart failure via Dicer post-translational modification

Deletion of adipocyte NOS3 potentiates high-fat diet-induced hypertension and vascular remodelling via chemerin

Circulating GDF11 exacerbates myocardial injury in mice and associates with increased infarct size in humans

Cardiomyocyte and endothelial cells play distinct roles in the tumour necrosis factor (TNF)-dependent atrial responses and increased atrial fibrillation vulnerability induced by endurance exercise training in mice

Women, lipids, and atherosclerotic cardiovascular disease: a call to action from the European Atherosclerosis Society

Chronic SIRT1 supplementation in diabetic mice improves endothelial function by suppressing oxidative stress

Single-cell profiling reveals age-associated immunity in atherosclerosis

Culprit plaque morphology determines inflammatory risk and clinical outcomes in acute coronary syndrome

Thrombin-activated interleukin-1α drives atherogenesis, but also promotes vascular smooth muscle cell proliferation and collagen production

Cationic proteins from eosinophils bind bone morphogenetic protein receptors promoting vascular calcification and atherogenesis

Air pollution and plaque healing in acute coronary syndromes

NLRP3 inflammasome and interleukin-1 contributions to COVID-19-associated coagulopathy and immunothrombosis

Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk

Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity

JCAD promotes arterial thrombosis through PI3K/Akt modulation: a translational study

Interferon regulatory factor-5-dependent CD11c<sup>+</sup> macrophages contribute to the formation of rupture–prone atherosclerotic plaques

Dynamic changes in chromatin accessibility are associated with the atherogenic transitioning of vascular smooth muscle cells<sup> </sup>

Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis

Neutralization of S100A4 induces stabilization of atherosclerotic plaques: role of smooth muscle cells

Adoptive transfer of CX3CR1 transduced-T regulatory cells improves homing to the atherosclerotic plaques and dampens atherosclerosis progression

Sirtuin 5 promotes arterial thrombosis by blunting the fibrinolytic system

Gut microbiota and myocardial infarction

A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography

High-density lipoprotein remodelled in hypercholesterolaemic blood induce epigenetically driven down-regulation of endothelial HIF-1α expression in a preclinical animal model

Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling

Identifying the anti-inflammatory response to lipid lowering therapy: a position paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology

Deficiency of the T cell regulator <em>Casitas B-cell lymphoma-B</em> aggravates atherosclerosis by inducing CD8<sup>+</sup> T cell-mediated macrophage death

Focus on echovascular imaging assessment of arterial disease: complement to the ESC guidelines (PARTIM 1) in collaboration with the Working Group on Aorta and Peripheral Vascular Diseases

PCSK9 deficiency reduces insulin secretion and promotes glucose intolerance: the role of the low-density lipoprotein receptor