Leveraging Data

Transforming complex data into practical tools

At the European Society of Cardiology we use diverse data sources, including our own real-world data, to create practical, trustworthy tools that improve decision-making in clinical practice and public policy. With a network of experts, we apply advanced modeling and risk prediction to turn complex information into clear insights for clinicians, policymakers, and others working to improve heart health. Our framework identifies who is most at risk, how risk affects communities, and where prevention efforts can have the greatest impact.

Cardiovascular Risk Collaboration Group

SCORE2 & SCORE2-OP

Established in 2019 by the ESC and the European Association for Preventive Cardiology, the Cardiovascular Risk Collaboration Group unites leading scientific partners to advance cardiovascular prevention for people across the globe.

Through joint research and data-driven innovation, the group develops and validates advanced risk assessment models that help identify individuals at higher risk of cardiovascular events, supporting earlier and more effective prevention.

Key outcomes of this collaboration include the SCORE2 and SCORE2-OP algorithms. Calibrated to four European risk regions using age- and sex-standardised cardiovascular mortality data, these models offer more precise, region-specific risk estimates that help clinicians and policymakers tailor prevention strategies to the needs of diverse European communities.

CVD Prevention Toolbox

REGION SPECIFIC TOOLS

SCORE2-Asia and SCORE2 LAC

Where a person lives can have a significant impact on their risk of developing cardiovascular disease, which is why ensuring prevention tools reflecting regional realities and supporting equitable cardiovascular health worldwide remains a core priority for our society.

We are proud to have expanded SCORE2 beyond Europe. SCORE2-Asia, developed with the Asian Pacific Society of Cardiology and the ASEAN Federation of Cardiology, provides tools adapted to countries across Asia.

We are also developing SCORE2 for use across Latin America and the Caribbean (SCORE2 LAC), in partnership with the Inter-American Society of Cardiology. Results and the publication of SCORE2 LAC will be presented at the ESC Congress 2026 in Munich.

Population-level prevention

The Burden of Disease

The ESC-Oxford Burden of Disease explores and evaluates cardiovascular risk at a population level, highlighting the real-world impact of CVD on health systems, economies and communities.

Using health economics, epidemiology and population modelling, the project quantifies the costs, mortality, morbidity and productivity losses associated with CVD.

As a join initiative with the University of Oxford’s Nuffield Department of Population Health, the Burden of Disease project combines our unique Europe-wide cardiovascular data networks – our National Cardiac Society members are major contributors - with Oxford’s methodological expertise in large-scale burden and cost-of-illness modelling.