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ESC Guidelines Licensing for AI, LLMs, and CDS Tools

ESC offers a dedicated licensing framework for technology teams building AI models, clinical decision support systems (CDS), or digital health platforms that incorporate ESC Guidelines and Scientific Documents. 

Under EU Directive 2019/790, non-commercial scientific research may be exempt from licensing. However, ESC has opted out of unrestricted reuse, meaning explicit permission is required for AI-related applications—even if the content is publicly accessible.

What You Can License

You can request permission to:

  • Use ESC content (full text, sections, or extracted data) to train generative AI models or large language models (LLMs).
  • Integrate ESC recommendations into AI-driven CDS tools or Electronic Health Record (EHR) systems for real-time clinical support.

Who Manages Licensing

  • For reproduction or translation not related to AI or CDS, licensing is handled by Oxford University Press (OUP).  Request via OUP
  • For AI training, LLM development, or CDS integration, licensing is managed directly by ESC. Request via ESC Licensing Form

Licensing Principles

  • Scientific research use may be free for eligible institutions and individuals.
  • Operational or commercial deployment—whether internal or external—requires a license.
  • ESC uses an honour-based declaration system. Misuse or false declarations may trigger retroactive fees and penalties.

Pricing For-profit Organisation / Company

€30,000 per guideline/document - €10,000 per additional guidelines for one year. 
Please select your entity type and intended use on the form to get the correct applicable price. Final pricing and license terms will be confirmed after review.