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Risk stratification in acute pulmonary embolism at moderate risk

Read by Kyriakos Yiangou

Main conclusion

The ratio TAPSE/PASP (TAPSE: Tricuspid Annular Plane Systolic Excursion ; PASP: Pulmonary Systolic Artery Pressure) can predict early CV death and hemodynamic decompensation in acute pulmonary embolism (PE) of moderate risk [OR = 0.0028; 95%; CI:0.010-0.087; P< 0.0001] and is superior to TAPSE or PASP alone (P = 0.017 and and P

Type of study

Retrospective study of a single center (from 2012 till 2019) of 627 patients with acute PE of moderate risk, evaluating the value of TAPSE/PASP ratio in assessing the primary end point (CV death and hemodynamic decompensation risk within 7 days) which was observed in 135 cases.

Main message for clinical practice

TAPSE and PAPS, easily derived by echocardiography, reflect systolic dysfunction of the right ventricle and its increased afterload. A TAPSE/PAPS ratio is < 0.4 a good predictor of early adverse events in patients with acute PE at moderate risk and may help in stratifying their risk and guiding their management