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Area of Expertise: Human stem cell-derived paracrine effect and extracellular vesicle biology for cardiac repair and regeneration
Dr. Sveva Bollini graduated in Medical Biotechnology and got her PhD from the University of Padova in Italy, where she studied the cardiomyogenic potential of human amniotic fluid stem cells. During her post-doctoral work, she worked on the lineage characterization of reactivated epicardium-derived progenitor cells for cardiac repair at UCL-University College London and at University of Oxford, in UK.
In 2014 she was presented with the “Rita Levi Montalcini” Young Investigator Award from the Italian Ministry of Research and Education (MIUR) and invited back to Italy to study the paracrine potential of the human amniotic fluid stem cell secretome (i.e. the whole of cell-secreted soluble factors and extracellular vesicles) to boost endogenous heart repair mechanisms. Currently she is an Associate Professor in Experimental Biology in the Department of Experimental Medicine, University of Genova in Genova, Italy. Her research mainly focuses on the functional characterisation of human fetal and perinatal stem cell secretome to resurge myocardial renewal, following injury (i.e. myocardial infarction and drug-induced cardiotoxicity).
Area of expertise: Autophagy and Cardiovascular Aging
Mahmoud is a research fellow at the Clinical Department of Cardiology at the Medical University of Graz, Austria. After studying human medicine in Egypt and Spain as well as basic cardiovascular science in Portugal, he joined the Graz experimental cardiology team in Austria. There, he developed an immense interest in the molecular mechanisms of cardiovascular aging and potential interventions that could delay disease and extend lifespan. His quest for anti-aging therapies led to discovering the cardio-protective and longevity-promoting effects of the natural autophagy-inducer and caloric restriction mimetic spermidine. He has received various prestigious awards for this finding including, but not limited to, the Sanofi Aventis Prize (2017) and the European Society of Cardiology young investigator award of the Heart Failure Association (winter meeting, 2017).
Currently, he is experimenting on other novel and feasible strategies to slow aging, meanwhile taking to the clinics those backed with sufficient preclinical evidence for human translation.
Area of expertise: Cellular and Translational Electrophysiology in Atrial Arrhythmopathy, Cardiac Tissue Remodeling
Dr. Constanze Schmidtcurrently works as physician scientist at Heidelberg University Hospital after her education in internal medicine and clinical cardiology with focus on cellular and clinical electrophysiology. She studied medicine and physics at Georg August University Göttingen, Germany. During her post-doctoral work, she studied the role of two-pore domain potassium channels in atrial fibrillation. Consecutively, she established her own laboratory focused on regulation of cardiac ion channels in thepathogenesis of atrial arrhythmopathyand investigation of new compounds in atrial fibrillation models for new antiarrhythmic applications. She received numerous research scholarships and awards from national and international foundations (Young Investigator Award Basic Science Finalist of the American Heart Rhythm Society, 2014; Olympia-Morata funding program, 2014-16; OskarLapp research award 2016 of the German Cardiac Society; August Wilhelm and Liselotte Becht research award 2017 of the German foundation for heart research).
Area of expertise: Calcium Handling, Excitation-Contraction Coupling, Stem Cells
Albano received his PhD in Neurobiology at the Faculty of Pharmacy in Montpellier (France) in 2007. He then worked as a postdoctoral research scientist at Columbia University Medical Center in New York City (USA) for 4 years. He was granted the European Marie-Curie Fellowship (2011) and the European Society of Cardiology grant (2012) to build up a team on human pluripotent stem cell-derived cardiomyocytes at Masaryk University Faculty of Medicine in Brno (Czech Republic). Albano was recruited as a permanent researcher by the French National Institute for Health and Medical Research (INSERM) in 2014. He has experience in basic cardiac physiology, calcium handling, ion channel biophysics as well as in human pluripotent stem cell-derived cardiomyocytes to model inherited cardiac arrhythmias.
Area of expertise: Inflammation and Cardiovascular Disease
Jyoti studied Biochemistry at Warwick University (UK) with a year placement at the Health Protection Agency, where she became interested in immunology and disease pathology which was followed by a PhD at Oxford University in inflammation and atherosclerosis in (2007-2011). During her post-doctoral work, she studied the role of a novel mediator of chemokine receptor signalling in aortic aneurysm formation which resulted in British Atherosclerosis Society Young Investigator Award in 2014. In 2015, she was awarded a British Heart Foundation Centre of Research Excellence Intermediate Transition Fellowship at Oxford University to develop her research interests on the mechanisms behind leukocyte trafficking in the response to acute myocardial infarction and their impact on healing of the heart.
Area of expertise: cardiovascular regeneration, cell-based cardiac repair
After completing her PhD in cardiovascular biology at the University Medical Center in Utrecht, Anke secured a fellowship that allowed her to spend 2 years as a postdoctoral research fellow based at both University College London and Oxford University. Currently she is a senior researcher at the department of Molecular Cell Biology, Leiden University Medical Center (LUMC). Her research group is funded by several prestigious grants including a VENI from The Netherlands Organisation for Scientific Research (NWO), and a LUMC Research Fellowship. Her research in (stem) cell biology focuses on translational cell-based therapies for myocardial infarction and remodelling, as well as on the regenerative potential of the cardiovascular system.
Area of expertise: Molecular and Translational Vascular Biology and Medicine
Dr. Konstantinos Stellos is a physician scientist at the Goethe University Hospital Frankfurt trained in vascular immunology, internal medicine and clinical cardiology at the University of Tubingen and Goethe University Frankfurt, Germany. Currently, his laboratory focuses on the role of functional transcriptomics (RNA modifications) in the regulation of coding and non-coding RNAs in vascular inflammatory diseases and investigates the clinical value of novel biomarkers in cardiovascular risk stratification. He has won numerous research scholarships and awards including the Else Kröner Memorial Scholarship in 2013 by the Else Kröner-Fresenius Foundation and the American Heart Association Young Investigator Award of the Council on Functional Genomics and Translational Biology in 2015.
Area of expertise: Cardiac Cellular Electrophysiology and Calcium Handling, Arrhythmias
Niels is professor of molecular pharmacology at the Institute of Pharmacology at the Georg-August University Göttingen. He graduated and received his MD from the University of Dresden in 2007. He worked as a postdoctoral scientist at the Institute of Pharmacology in Dresden, at the Medical Faculty Mannheim, Heidelberg University and at the Institute of Pharmacology at the Duisburg-Essen University. In 2013, he obtained the specialization in Pharmacology and Toxicology. His field of interest is the regulation of ion channels and calcium signaling in the normal and diseased heart. He has received numerous research awards e.g. the Oskar-Lapp-Research Award (2015) from the German Cardiac Society and the Best of Basic Science Abstracts Award from the American Heart Association (2013).
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