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European database on catheter-directed treatment of pulmonary embolism

EuroPE-CDT

EuroPE-CDT s is an investigator initiated European database on Catheter Directed Treatment of Pulmonary Embolism (EuroPE-CDT).  The main goals of EuroPE-CDT is to assess the currently applied CTD techniques and strategies in PE patients and to determine the short term efficacy and safety of this invasive procedure.



EuroPE-CDT.PNG

 

Rationale of EuroPE-CDT: Thrombolysis or embolectomy is recommended in hemodynamically unstable patients with acute PE and it should also be considered when initially normotensive PE patients deteriorate despite adequate anticoagulation. Unfortunately, almost half of such patients are not thrombolyzed due to high bleeding risk, and they should be referred urgently for surgical or catheter directed embolectomy (CDT). However, due to limited immediate availability of surgical embolectomy in majority of centers CDT is becoming a real therapeutic option. Indeed, currently there is an increasing interest in CDT in high and intermediate high risk PE patients. Pulmonary Embolism Response Teams (PERTs) are being established in many European PE centers. A wide range of mechanical systems for CDT are applied. In some patients also low dose local thrombolysis is used. However, only few randomized trials on CDT have been published so far, and no real-world European data on efficacy and safety of CDT is still available. We are convinced it is time to summarize current  European CDT experience.

Anonymized data of consecutive PE patients treated with CTD in European centers will be collected in the database. Prospective and retrospective cases are also allowed when required data can be provided. We intend to obtain data on basic patients characteristics, PE severity (blood pressure, heart rate, echocardiographic parameters, plasma levels of biomarkers), CTD procedure and short term outcome. We are planning to include approximately 150-200 patients suitable for analysis by the end of 2020.

EuroPE-CDT Steering and Organizing Committee

Piotr Pruszczykk, Poland

Stavros Konstantinides, Germany

Nicolas Meneveau, France

David Jimenez, Spain

Miguel Ángel De Gregorio, Spain

Marek Roik, Poland

Mateusz Jermakow, Poland, project coordinator

EuroPE-CDT Website