Editorial - July 2023

Dear Members of the ESC Working Group on Atherosclerosis and Vascular Biology,

Summer has started and vacation has begun or is just around the corner! For many members of our Working Group (WG), summer started off with the Gordon Research Conference (GRC) on Atherosclerosis, which was held in Barcelona, Spain. We enjoyed a week of superb scientific presentations, meeting old friends, making new friends, sharing new ideas and starting novel collaborations. This was followed by a great EVBO summer school, also in Barcelona, where our young scientist could enjoy lectures on the latest insights in the vascular biology and atherosclerosis field.  

We hope that all of you can now relax a little and prepare for the next season of great cardiovascular science, starting off with the annual ESC Congress from 25-28 August 2023 in Amsterdam, The Netherlands. We are all looking forward to meeting all our members in Amsterdam. Congratulations to Doctors Xiaoqun Wang and Julian Uwe Gabriel Wagner, the two winners of the WG Awards selected from the best abstracts in our field! Make sure you attend their presentations:

• Increased 12/15-lipoxygenase by disturbed flow promotes endothelial dysfunction and the development of atherosclerosis
  Presenter: Xiaoqun Wang (Rui Jin Hospital- Shanghai Jiaotong University School of Medicine - Shanghai, China) Time: 09:10
  Novel mechanisms for insights into atherosclerosis 
  Saturday, 26 August at 09:00-10:00
  Abstract session - Science Box 3
• Vascular senescence controls the neuro-cardiac interface in the aging heart
  Presenter: Julian Uwe Gabriel Wagner (Wolfgang Goethe University - Frankfurt, Germany)
  Vascular homeostasis: senescence and oxidative stress
  Sunday, 27 August at 13:15-14:00
  Moderated ePosters – Station 8

To make life easier, we have selected ESC sessions that we think are a ‘must attend’ for all our members (and where you can see our nucleus members in action):

25 August:

• 11:15, PODGORICA: Cellular communications at single-cell resolution in cardiovascular diseases
• 12:45, Science Box 2: Young Investigator Awards in Basic Science
• 14:00, PODGORICA: Heart Brain Interactions in cardiovascular disease
• 16:15, Station 8: Vascular Dysfunction
• 16:30, OSLO: Targeting the spectrum of atherogenic lipoproteins: what to do and how to do it

26 August:

• 8:30, PODGORICA: Novel targets for treatment of atherosclerosis
• 9:00, Science box 3: Novel mechanisms for insights into atherosclerosis
• 14:00, PODGORICA: RNA therapeutics for cardiovascular disease
• 15:30, Hub MONDRIAN: ESC William Harvey Lecture in Basic Science
• 16:15, Station 8: Platelets and thrombomodulin
• 16:30, OSLO: Women, dyslipidemia and atherosclerosis: what is different?

27 August:

• 13:15, Station 8: Vascular homeostasis: senescence and oxidative stress
• 14:00, PODGORICA: Organelle stress in cardiovascular disease
• 14:00, Science box 1: Coronary Plaque characterization: from proteomics to AI
• 13:15, Station 8: Inflammation as key driver of vascular dysfunction
• 14:00, PODGORICA: Ageing and stress responses in cardiovascular disease

28 August:

• 14:15, Station 8: Atherosclerosis
• 16:45, Science box 2: Novel pathomechanisms identified by single cell technologies

For further details on the sessions, please visit the ESC Congress 2023 scientific programme.

We also have some summer reading recommendations from our nucleus members:

• Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture
• Cationic proteins from eosinophils bind bone morphogenetic protein receptors promoting vascular calcification and atherogenesis
• Single-cell profiling reveals age-associated immunity in atherosclerosis
• Peripheral Ischemia Imprints Epigenetic Changes in Hematopoietic Stem Cells to Propagate Inflammation and Atherosclerosis
• Air pollution and plaque healing in acute coronary syndromes
• Flow-induced reprogramming of endothelial cells in atherosclerosis
• Protective Effect of Ticagrelor Against Infective Endocarditis Induced by Virulent Staphylococcus aureus in Mice
• NLRP3 inflammasome and interleukin-1 contributions to COVID-19-associated coagulopathy and immunothrombosis
• Chronic SIRT1 supplementation in diabetic mice improves endothelial function by suppressing oxidative stress 
• JCAD promotes arterial thrombosis through PI3K/Akt modulation: a translational study 
• Distinct Roles of DRP1 in Conventional and Alternative Mitophagy in Obesity Cardiomyopathy

And if you are looking for a dream job in Graz, Austria, please click this link:

https://jobs.escardio.org/post-doc-at-physiology-pathophysiology-medical-university-in-graz-austria-14993f4dcedd

This newsletter is for YOU, so if you want to recommend papers, conferences etc.. feel free to send this content to us.

Looking forward to seeing you all in August at ESC Congress 2023 in Amsterdam!

Yours sincerely,

Isabel and Esther
On behalf of the communication team of the Working Group on Atherosclerosis and Vascular Biology.