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What is new in rehabilitation following cardiac surgery?

comment by Maria Simonenko, EAPC Secondary Prevention and Rehabilitation Section

Cardiovascular Rehabilitation

Aerobic exercise is a critical component of cardiac rehabilitation (CR) for patients who have undergone cardiac surgery [1]. A lot of patients were included in the study of M.P. Doyle et al., but the pooled mean age was 66±10 years, and pooled mean percentage of male patients was 73% [1]. So there will be more practical benefits to include younger patients and female ones too.

According to previous studies, women had a significantly lower peak VO2 than men, but had better survival at all levels of exercise capacity [2]. The current practice of uniform application of peak VO2 as an aid to determine heart transplantation (HTx) timing should be re-examined [2].

n addition, high-intensity aerobic interval exercise (HIIE) appeared to be safe in this selected population of men with mild to moderate systolic chronic heart failure and the HIIE protocol with short intervals (30 s) and passive recovery appeared to be optimal among those tested in the study of P. Meyer et al. [3].

Moreover, exercise based CR in the modern era aims to improve aerobic and functional capacity through the use of aerobic based exercise such as walking and stationary cycling, providing benefits of symptom amelioration, attenuation of cardiac disease progression and reduced hospital admissions and mortality [4,5,6,7,8]. X. Yang et al. showed in their study that exercise was not clearly associated with reductions in cardiac death, the recurrence of myocardial infarction (MI), repeated PCI, CABG, or restenosis [9].

According to G.O. Dibben et al., there is moderate evidence of an increase in physical activity (PA) with CR participation compared with control [10]. Patients performing high frequency aerobic exercise reached most functional milestones significantly earlier than those performing low-frequency exercise, and aerobic exercise improved cardiac autonomic function assessed by heart rate variability, compared with usual care [1,11,12].

High-quality trials are required, with robust PA measurement and data analysis methods, to assess if CR definitely leads to important improvements in PA [10]. Post-HTx patients maintain a moderately active lifestyle. Measures of exercise tolerance generally are related to recent daily recreational activities in patients after HTx, but these associations are modest. The many physiologic factors unique to heart transplanted recipients likely play a more important role than deconditioning in determining exercise tolerance in these patients [13].

However, M.P. Doyle et al. have not discussed in their study the difference of CR after cardiac surgery procedures. T. Kavanagh et al. suggested that exercise capacity, as determined by direct measurement of VO2peak, exerts a major long-term influence on prognosis in men after MI, CABG, or ischemic heart disease (IHD) and can play a valuable role in risk stratification and counseling [14].

Aerobic exercise commenced early after cardiac surgery significantly improves functional and aerobic capacity following cardiac surgery at hospital discharger compared with current usual physiotherapy care and may provide improvements in aerobic capacity in the short to medium term [1].

In conclusion, aerobic exercise training improves peak oxygen consumption in healthy, elderly and cardiac patients and we should have more studies in this field.

 

Note: The content of this article reflects the personal opinion of the author and is not necessarily the official position of the European Society of Cardiology. 

References

References:

  1. Mathew P Doyle, Praveen Indraratna, Daniel T Tardo, Sheen CS Peeceeyen, Gregory E Peoples - Safety and efficacy of aerobic exercise commenced early after cardiac surgery: A systematic review and meta-analysis, European Journal of Preventive Cardiology, 2019, Vol. 26(1), 36-45 DOI: 10.1177/2047487318798924
  2. Sammy Elmariah, Lee R. Goldberg, Michael T. Allen, Andrew Kao – Effects of gender on peak oxygen consumption and the timing of cardiac transplantation, Journal of the American College of Cardiology, Vol. 47, № 11, 2006 DOI: 10.1016/j.jacc.2005.11.089
  3. Philippe Meyer, Eve Nordmandin, Mathieu Gayda, Guillaume Billion, Thibaut Guidaud, Laurent Bosquet, Annick Fortier, Martin Juneau, Michel White, Anil Nigam – High-intensity interval exercise in chronic heart failure: protocol optimization, Journal of cardiac failure, vol. 18, № 2, 2012. 126-133 DOI: 10.1016/j.cardfail.2011.10.1010
  4. Anderson L, Thompson DR, Oldridge N, et al. Exercise- based cardiac rehabilitation for coronary heart disease. Cochrane Database Syst Rev 2016; 1: CD001800
  5. Niebauer J. Is there a role for cardiac rehabilitation after coronary artery bypass grafting? Treatment after coron- ary artery bypass surgery remains incomplete without rehabilitation. Circulation 2016; 133: 2529–2537
  6. Taylor RS, Brown A, Ebrahim S, et al. Exercise-based rehabilitation for patients with coronary heart disease: Systematic review and meta-analysis of randomized con- trolled trials. Am J Med 2004; 116: 682–692
  7. Kulik A, Ruel M, Jneid H, et al. Secondary prevention after coronary artery bypass graft surgery: A scientific statement from the American Heart Association. Circulation 2015; 131: 927–964
  8. Kachur S, Chongthammakun V, Lavie CJ, et al. Impact of cardiac rehabilitation and exercise training programs in coronary heart disease. Prog Cardiovasc Dis 2017; 60: 103–114
  9. Xinyu Yang, Yanda Li, Xiaomeng Ren, Xingjiang Xiong, Lijun Wu, Jie Li, Jie Wang, Yonghong Gao, Hongcai Shang, Yanwei Xing – Effects of exercise-based cardiac rehabilitation in patients after percutaneous coronary intervention: A meta-analysis of randomized controlled trials, Scientific reporta, 7:44789, 1-9 DOI: 10.1038/srep44789
  10. Grace Olivia Dibben, Hasnain M. Dalal, Rod S. Taylor, Patrick Doherty, Lars Hermann Tang, Melvyn Hillsdon – Cardiac rehabilitation and physical activity: systematic review and meta-analysis, Heart, 2018; 0:0-9 DOI: 10.1136/heartjnl-2017-312832
  11. Hirschhorn AD, Richards D, Mungovan SF et al. - Supervised moderate intensity exercise improves distance walked at hospital discharge following coronary artery bypass graft surgery – a randomised controlled trial. Heart Lung Circ 2008; 17: 129–138.
  12. Stein R, Maia CP, Silveira AD, et al. - Inspiratory muscle strength as a determinant of functional capacity early after coronary artery bypass graft surgery. Arch Phys Med Rehabil 2009; 90: 1685–1691
  13. Jonathan Myers, Lars Gullestad, Daniel Bellin, Heather Ross, Randall Vagelos, Michael Fowler – Physical activity patterns and exercise performance in cardiac transplant recipients, Journal of Cardiopulmonary Rehabilitation, 2003; 23:100-106
  14. Terence Kavanagh, Donald J. Mertens, Larry F. Hamm, Joseph Beyene, Johanna Kennedy, Paul Corey, Roy J. Shephard – Prediction of long-term prognosis in 12 169 men referred for cardiac rehabilitation, Circulation, 2002; 106:666-671 DOI: 10.1161/01.CIR.0000024413.15949.ED