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Late-Breaking Science submission rules and guidelines

Frontiers in CardioVascular Biomedicine (FCVB)

Late-Breaking Science includes the following types of applications:

Late-Breaking Clinical Trial
Late-Breaking Registry Results
Clinical Trial Update

For FCVB 2022, you need to select:

BASIC & TRANSLATIONAL LATE-BREAKING SCIENCE - Reserved for late submissions of important findings in Basic and Translational Cardiovascular Science

Submission Guidelines

Submissions are only possible through the online submission services.

Submission deadline is Monday 14 February 2022, 12:00PM noon CET.

Draft Status

If you do not click on the submit button (Step 5 of the submission process), your application will be saved in Draft Status, you can re-access it to complete it at any time.

Please note that applications that are in draft status after the deadline will not be considered for selection.

Changes and corrections

Once submitted, it will not be possible to make any corrections to the content or other information (such as presenter details, topic, etc.). In order to correct your submission, you must withdraw it and submit a new version prior to the deadline (see below for withdrawal procedure). Note that such a replacement of your submission is not possible after the submission deadline.


If you want to withdraw a Late-Breaking Science already submitted, please notify us as quickly as possible at stating the title and number to be withdrawn.

Note that withdrawal is still possible after the submission deadline.

Data previously submitted as an abstract to FCVB 2022

If you have already submitted an abstract (during the Call for abstracts) on this study, indicate the abstract number.

If your study is accepted as a late-breaking submission, you will be asked to withdraw your earlier abstract submission.

In order to submit, you must complete the following five steps -

Step 1 - General information

Type of submission

You must select one of the following types of submission under which your research can be best classified:

LATE-BREAKING CLINICAL TRIAL - Reserved for first presentations of the primary endpoint(s) of a new clinical trial  

REGISTRY - Reserved for presentations of data not previously presented from a new or existing registry

CLINICAL TRIAL UPDATE - Reserved for presentations of new data or secondary analysis of a trial where the primary data have been presented previously

For FCVB 2022, you need to select: BASIC & TRANSLATIONAL LATE-BREAKING SCIENCE - Reserved for late submissions of important findings in Basic and Translational Cardiovascular Science


Study details

Topic - Select one topic from the list of topics shown to index your research.

Full Title of study - A maximum of 200 characters typed in lower-case letters, except for abbreviations and study names. Please be aware that your title might be truncated if you copy and paste it into the field.

Acronym - If the study to be presented is known through an acronym, please indicate the name of the study (e.g. "EMIT") in this field as well as the full name of the acronym (e.g. "European Mizaverol Trial"). This is a mandatory field for Late-Breaking Clinical Trial and Clinical Trial Update submissions. 

Short title for programme - Enter a short title for ESC programme (ESC TV/ Scientific programme/ESC 365….). Indicate the acronym followed by a short title for your trial. This title will be used as presentation title if accepted.

Funding Acknowledgements - All sources of financial support (including governmental grants) for this research should be listed under this heading. All grant funding agency abbreviations should be spelled out.

Trial Registration number - If available, indicate any reference to your trial registration (number, website link….).

Expected date of trial completion - Applies only for Late-Breaking Clinical Trials and Basic & Translational Late-Breaking Science – Please enter the date at which you expect to have all results ready for communication.

On behalf of - If applicable, a name of a study group can be mentioned here. Do not list any author names in this field.


Study confidentiality and embargo requirements

Data previously submitted as an abstract to FCVB 2022 -

If you have already submitted an abstract (during the Call for abstracts) on this study, indicate the abstract number.

If your study is accepted as a late-breaking submission, you will be asked to withdraw your earlier abstract submission.

Submitted Late-Breaking Science should not have been published in any journals and/or online publications nor presented at any congresses. This embargo applies until presentation at FCVB 2022.

Nevertheless, simultaneous publication is authorised.

If you have already submitted or intend to submit your data/results for simultaneous publication, indicate the name of the journal/publication.

Publication information - Journal Publication information is required – specify whether the data have been submitted or will be submitted for simultaneous publication.

Although the data may be submitted to a journal for consideration, it may not be published before the date of the presentation at FCVB 2022. The embargo must remain in place until the start time of the session in which the data will be presented.


If you do not indicate that a publication in relation to your research is already planned, then the ESC proposes to highlight accepted applications through the European Heart Journal or another member of the ESC Journal Family. Accepted applications will be shared with the related journal’s editorial team in the strictest confidence, and they may contact you directly.

Step 2 - Author information and Author list

Your submission must list at least 1 author in order to be completed.

Author list

Enter each author and affiliation using the “Add a new author” module.

The presenter must be included in the author list and positioned as First author.

You can enter up to 15 authors.

NB: The submitter certifies that he/she has permission from all persons he/she enters as co-authors to be listed in this abstract and that they are aware that their names will appear in publications.

If none of the authors is available to present during the congress, the application must be withdrawn.


This is a mandatory entry.

Select your institution when you create the presenter and the authors. Once you have entered your city, a list will automatically appear from which you can select your institution. If your institution is not in the list, you have the possibility of creating it. If your city is not in the list, please enter it, press enter then add your institution.

Presenter during the congress - Reconfirm the name of the presenter

Principal investigator - Indicate the name of the principal investigator

Step 3- Study outline

In this part of the submission, you will be asked to provide some outline information depending on the type of submission selected information requested will vary

Multi-centre study

Purpose – You need to summarize the purpose of the study

Design – Study Design information

Sample Size information (Number of Subjects, number of groups, number of persons per group, Population studied info and Intervention performed)

Outcome(s) (Primary endpoints & Secondary endpoints) – 2 sentences max per header

Step 4 - Research content

All abstracts must be submitted in English with accurate grammar and spelling suitable for publication.

Abstracts submitted on animal studies: Study must follow the "Principles of laboratory animal care" (NIH Publication no. 85-23 revised 1985) and be in agreement with the national law if applicable.

Please note that any medical research involving human subjects must conform to the principles of the Declaration of Helsinki of the World Medical Association and must have been approved by an IRB.

Do not cut and paste symbols into your text.

Use the symbols provided when you click on the Ω button.

Recommended content structure

Background - In an initial paragraph, provide relevant information regarding the background and purpose of the study, preferably in no more than one or two sentences.

Methods - Briefly state the methods used. Especially for trials where results are not yet available, information on endpoints and statistical power are desirable.

Results - Summarize the results, if available, in sufficient detail to support the conclusions.

Conclusions - State the conclusions reached. It is not satisfactory to state “the results will be discussed.”

If results are not available yet but will be available by the time of the presentation, explain the main endpoints that you expect to be able to describe and the conclusions that can be drawn.

NB – Your submission will be used ONLY for review by the selection committee and not published as such by ESC.

For accepted submissions, ESC Press team will have access to this submitted abstract to write the Press Release which you will be asked to review prior to finalisation.

Other Information for content -

In the abstract, use generic drug and product names whenever possible.

The use of commercial drug names, brands and registered trademarks is strictly prohibited.

Drugs should be referred to by the active substance or pharmacological designation.

For experimental and investigational substances, the chemical name should be given.

The names of novel or unique devices can be cited after an explanation of their specific characteristics, but without reference to the company name.

Technical information for content -

Size - The maximum abstract size is 50 lines of 75 characters (3750 characters).

Use the save and refresh button at the bottom in order to display the overall size of the abstract in percentage (shown on the left side of the screen). The programme then converts the size in % to display to you when you register it as a draft.

The character limit does not include the title, nor the authors and the image (if any). Only the abstract text, table and spaces are taken into account.

Table - The table field holds a table without surrounding text. Do NOT COPY your table into the field. You must RECREATE your table using the tools provided.

The maximum size of the table is 12 columns and 20 rows, and you can only enter one table. The title field is optional.

Image - Your Image file must meet the following criteria:

  • Format: JPEG or GIF
  • Size: less than 1000 Kb
  • Measures between 800 pixels(x) x 600 pixels(y)
  • Please make sure that your picture is readable on the preview.
  • You can only enter one picture, and the title field is optional.

Step 5 - Late-Breaking Science submission preview

Please read through the preview carefully before submitting it, as you cannot change it once submitted.

You will be asked again to confirm that the research has not been published or presented and that you have read and approved the submissions rules (see below for the details of the submission and presentation rules).

Do not forget to click on the Submit button to validate your submission.

You will receive an automatic e-mail confirmation. If you do not receive this confirmation for one or more of your submissions, please contact the Scientific Programme Department at

Submission Rules


There is no limit to the number of Late-Breaking Science applications an author may submit, but you should not submit the same research twice, even under a different topic.

If you submit two applications with the same title, content, the submission service will automatically keep the most recent one and withdraw the other.

Note that duplicate drafts will not be deleted nor considered.

Embargo and Publication

The submitter, on behalf of all co-authors, accepts responsibility to ensure that data is not disclosed prior to the session itself.                                                                

The clinical trial results presented during the Congress are embargoed until the start of the session in which the presentation is scheduled. Clinical trial sponsors must comply with the embargo.

The embargo means that results from the trial cannot be presented or announced in any forum (written or oral) except at closed investigator meetings prior to the ESC news conferences. Presentation in Satellite Symposia prior to the session is also prohibited.

If an investigator or sponsoring organisation believes that it is required for legal reasons or for issues related to public health to release information about a late-breaking clinical trial prior to the end of the embargo, the investigator or organisation must notify the ESC Media Relations Department in advance in writing at

The written notification must provide the legal rationale for requiring early disclosure. Notification must also include who would receive the information, how and when the information would be disclosed, and a description, template release, or copy of any press releases or other public statements that would be distributed. With appropriate advance notice, the ESC can provide general advice about how such disclosures might impact its inclusion/continued inclusion in the ESC programme. The ESC reserves the right to remove the presentation from the Hot Line session, to remove the study from consideration for a press release or other promotions, to remove the study from the scientific program entirely.

If above rules are violated, the presentation may be withdrawn from the programme. Failure of investigators or sponsors to honor this embargo will also jeopardize future acceptance of clinical trials of the sponsors and presentations of the principal investigator at scientific sessions of the ESC Congress.


Submission of an application constitutes a commitment by the author(s) to present if accepted. Failure to present, upload the presentation by the deadline and register for the meeting will lead to the withdrawal of the research by the set deadlines.

Satellite Symposia occurring prior to the Hot Line sessions cannot present the data contained in these sessions.

Prior private presentation to the trial investigators is acceptable, but the investigators must be instructed to obey the embargo rules.


Affirmation of originality and copyright transfer of statement

The submitter hereby affirms that the work submitted is original, except for extracts from copyrighted works fully authorised by the copyright holders, and that all statements declared as facts are based on thorough examination and investigation for accurateness.

By submitting your work to the ESC, you consent to have authors’ names, affiliation and biographical material being used in connection with the publication of your work.

Author(s) represents and warrants that he/she/they is/are sole author(s) of the work, that all authors have participated in and agree with the content and conclusions of the work, and that the work is original and does not infringe upon any copyright, proprietary, or personal right of any third party.

Submitting/Presenting published or already presented work will jeopardize future acceptance.

Author(s) retain the right, after presentation at the Congress, to subsequently include the work in articles, books, or derivative works that he/she authors or edits provided said use does not imply the endorsement of the ESC.

The submitter signs for all co-authors and accepts responsibility on the present rules for submission and presentation for transferring copyright on behalf of all co-authors.

For accepted submissions, ESC Press team will have access to this submitted abstract to write the Press Release, which you will be asked to review prior to finalisation.

ESC reserves the right to provide its press releases a few days before public release to a selected list of Journalists who have previously agreed in writing to respect the ESC embargo policy.

The content belongs to the author(s). However if the study is accepted for presentation, the presenter can agree, on behalf of all co-authors, to transfer and assign to the ESC free of charge, on a non-exclusive basis, for twenty years the rights to edit, publish, reproduce, distribute copies and prepare derivative works such as press release and/or educational products, using all communication tools and means, now known or hereinafter developed, including any and all digital means and any and all supports or forms of media, now known or hereinafter developed, in particular all paper, analog, digital, numerical and electronic media, including Internet, Intranet and Extranet sites and social media. This includes use in indexes or search databases in print, electronic, or other media.

Conflict of interest

The Congress Programme Committee requests all presenters to disclose their potential conflict(s) of interest at the time of acceptance of presentation (agreement form submission). It is also the responsibility of the presenter to disclose any potential conflict(s) of interest from co-authors pertaining to the presentation on the presentation itself (as may be required).
This will allow the audience to take potential conflicts of interest into account when assessing the objectivity of the presentation.
A potential conflict of interest may arise from various relationships, past or present, such as employment, consultancy, investments and stock ownership, funding for research, family relationship, etc.
All potential conflicts of interest must be stated.
This pertains to relationships with pharmaceutical companies, biomedical device manufacturers, or other corporations whose products or services are related to the subject matter of the article. Such relationships include, but are not limited to, employment by an industrial concern, ownership of stock, membership on a standing advisory council or committee, being on the board of directors, or being publicly associated with the company or its products. Other areas of real or perceived conflict of interest could include receiving honoraria or consulting fees or receiving grants or funds from such corporations or individuals representing such corporations.


Data Privacy
By certifying that you have read these Submission rules, you also confirm having received the prior approval from the co-authors to provide their data to the ESC.

The information collected in this CALL FOR LATE-BREAKING SCIENCE is subject to data processing to proceed with the elaboration of FCVB 2022 scientific programme.

Provision of personal data is a statutory requirement to list the authors who have contributed to the research submitted.

The recipients of the data are ESC Staff who process the submissions and the ESC Committees and volunteers involved in the scientific programme.

Data collected will be kept for 20 years.

Transfer of personal data to ESC Staff, contractors as well as other ESC related scientific organisations occurs for production, promotion and dissemination of the Congress Content.

In accordance with the chapter 3 of the European Regulation 2016/679 with regards to data protection, you have the right to request from ESC, access to and rectification or erasure of your personal data or restriction of processing concerning your data or to object to processing as well as the right to data portability. This is done thru withdrawal of the submission according to the terms and conditions of withdrawal.

For such, please contact (together with a proof of identity):

Data Privacy
European Society of Cardiology
Les Templiers
2035 Route des Colles
CS 80179 Biot

Or by email to

You have the right to lodge a complaint with a supervisory authority, and for information, ESC has appointed a Data Protection Officer that you can reach at

Applicable law

All the rules pertaining to the present submission are governed by and construed in accordance with the laws of France without regard to any conflicts of laws principles thereof that would require the application of the law of any other jurisdiction. Any disputes arising in relation hereto shall be submitted to the exclusive jurisdiction of the French Tribunal de Grande Instance located in Grasse, France.


Speakers cannot present in more than one Late-Breaking Science Session.

Results -

After the submission deadline, the system will be closed, and submissions will be forwarded to the Reviewing Committee. Changes or corrections will not be possible after the deadline.

The final selection will be made by the Selection Committee by mid-March 2022. The Selection Committee will determine the format, day and time of presentation. No rescheduling or changes will be possible.

Results announcement -

An email message will be sent to the submitter mid-March 2022 with a report on the status of their submission (accepted or rejected).

If the Late-Breaking Science is accepted, notification and further instructions concerning the presentation format will be sent directly to the assigned presenter (indicated in the submission form).


The presenter will be asked to submit an agreement form online before the given deadline.

If the presenter is contacted by other organisations for interview, articles etc, the presenter must ascertain adherence to the embargo policy before providing any information to third parties.