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45th EWGCCE Meeting

24/04/2021 09:30 25/04/2021 00:00 Europe/Paris 45th EWGCCE Meeting

EWGCCE Annual Meeting is the combination of the best lectures given by renowned international experts and an incredible friendly and stimulating spirit.


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The Annual Meeting of the ESC Working Group on Cardiac Cellular Electrophysiology

The ESC Working Group on Cardiac Cellular Electrophysiology (EWGCCE) 45th meeting, will be held with EHRA, as an online congress on 24 April. 

As usual, the meeting gathers young researchers and high-level international experts in cardiac cells and provides an overview of topical issues in signalling, ion channels, arrhythmias, models and techniques at experimental and clinical level. There will be online poster sessions and some abstracts will be selected to be presented in the symposia.

Key dates

Category Deadline
Abstract submission deadline 14 January
Abstract results announcement Early February
Early fee registration deadline 9 March
Late fee registration deadline 9 May


Registration fees

Description Early fee
(until 9 March)
Late fee
(from 10 March until 25 April)
Working Group on Cardiac Cellular Electrophysiology Member €75 €90

Registration fees include applicable local VAT.

Register Now

Become a member

This meeting is restricted to members of the ESC Working Group on Cardiac Cellular Electrophysiology. If you're not a member yet, you can join for free.

Scientific programme - Saturday 24 April

  07:30 - 08:30 Live Abstract session
Chairpersons: E Passini (Oxford, GB) - KE Odening (Bern, CH)

Human-based computational and experimental investigation of disease mechanisms in mutation-specific hypertrophic cardiomyopathy
F Margara (Oxford,GB)

Development of a multiscale electromechanical computer model from cell to hemodynamics
A Lyon (Maastricht,NL)

Cholinergic regulation of cardiac pacemaker activity by L-type Cav1.3 channels
L Talssi (Montpellier,FR)

Functional characterization of drug responses in induced pluripotent stem cell-derived cardiomyocytes from a short QT syndrome type 5 patient
J Lee (Basel,CH)

Electro-mechanical and mechano-electrical interactions in healthy and drug-induced LQTS rabbit hearts
R Lewetag (Freiburg,DE)

Enhancing mutant IKS channel activity by increasing endogenous PIP2 levels and its interaction with PKA signalling pathway

Aminophylline affects the cardiac rat inward rectifier potassium current in a dual way
NJD Dourado Ramalho (Brno,CZ)

Beta-1 adrenergic receptors modulate pacemaker activity of mouse sino-atrial myocytes through L-type Cav1.3 channels
E Torre (Milan,IT)

  09:00 - 09:55 Neurohormonal disturbances and arrhythmias
Chairpersons: J Jalife (Ann Arbor, US) - L Sacconi (Sesto Fiorentino, IT)

09:00 The cardiac sympathetic network and cardiac electrical function
T Zaglia (Padova,IT)

09:12 Cardiomyocyte calcium signalling in cardiorenal syndrome
G Ruiz Hurtado (Alcorcon,ES)

09:24 CaMKII as a therapeutic target in catecholaminergic polymorphic ventricular tachycardia type 1
M Sadredini (Oslo,NO)

09:30 Glucagon-like peptide-1 directly increases heart rate and shortens atrial refractoriness: an in vivo and ex vivo study in pigs
AF Lubberding (Copenhagen N,DK)

09:36 Characterisation and modelling of the abnormal electrophysiological response under beta-adrenergic stimulation in hypertrophic cardiomyopathy
R Doste (Oxford,GB)

09:42 Neurohormonal disturbances and arrhythmias - discussion

  10:00 - 10:55 Structural microdomains in cardiomyocyte arrhythmogenesis 
Chairpersons: CA Remme (Amsterdam Z0, NL) - M Thomsen (Copenhagen, DK)

10:00 Dyadic plasticity in cardiomyocytes
W Louch (Oslo,NO)

10:12 Atrial t-tubule remodelling in heart failure
K Dibb (Manchester,GB)

10:24 When multiple caveolins make the difference: Cav1 partly compensates Cav3 alterations and rescues ion channels expression
P Benzoni (Milano,IT)

10:30 Desmosomal vulnerability renders left atria more susceptible to detrimental effects of androgenic anabolic steroids
LC Sommerfeld (Birmingham,GB)

10:36 OPN5 a new optogenetic receptor to study Gq signalling in the heart with light
A Wagdi (Goettingen,DE)

10:42 Structural microdomains in cardiomyocyte arrhythmogenesis - discussion

  11:00 - 11:55 Ion channel (dys)function
Chairpersons: M Bebarova (Brno, CZ) - DM Johnson (Milton Keynes, GB)

11:00 ORAI1- dependent intracellular calcium (dys)regulation
J Sabourin (Chatenay-Malabry,FR)

11:12 Ion-channel basis of circadian clock in the pacemaker
A D'souza (Manchester,GB)

11:24 The SCN5A point mutation M1875T, associated with familial atrial fibrillation, causes a gain-of-function effect of the cardiac Nav1.5 channel in atrial cardiomyocytes
M O'Reilly (Birmingham,GB)

11:30 Clinical, genetic and functional analysis of R562S-Kv7.1 mutation associated with long QT syndrome type 1
O Svecova (Brno,CZ)

11:36 Piezo1 and BKCa channels in human atrial fibroblasts: interplay and remodelling in atrial fibrillation
R Peyronnet (Freiburg,DE)

11:42 Ion channel (dys)function - discussion

  12:40 - 13:35 Carmeliet - Coraboeuf - Weidmann Lecture
Chairpersons: AM Gomez (Chatenay-Malabry Cedex, FR) - J Heijman (Maastricht, NL)

12:40 Repolarisation and electrical instability
A Zaza (Milan,IT)

13:30 Carmeliet - Coraboeuf - Weidmann lecture - discussion


Access the Scientific Programme 

45th WGCCE Networking & Scientific Discussion - Saturday 24 April 13:40 – 15:40

Meet your peers during the Networking & Scientific Discussion, restricted to members of the Working Group:

  • Welcome and introduction: 5min
  • Scientific discussion (Roundtables): 90min
    • Roundtable 1: Multiscale and Non-Myocyte Electrophysiology

    • Roundtable 2: Ventricular Arrhythmias

    • Roundtable 3: Pacemaking and Atrial Arrhythmias

  • Award ceremony: 9min
  • General assembly: 15min

Registration for this meeting is mandatory, free of charge, and open to all members of the ESC WG on CCE.

Register for the discussion

You will be asked to log into your My ESC.


The ESC Working Group on Cardiac Cellular Electrophysiology is pleased to offer a financial prize of 350€ to the 'best abstract presentations': 6 award winners will be selected amongst the presenters of the WGCCE e-posters, live abstracts and oral presentations.

Conditions: Candidates must be a Member of the ESC Working Group on Cardiac Cellular Electrophysiology

Poster presentations will be judged during the meeting by an expert panel of poster judges, who will select winners of the poster awards (two e-Poster award winners, two oral abstract winners and two oral presentation winners).

Prizes will be announced during the 45th WGCCE Networking & Scientific Discussion (Saturday 24 April from 13:00 to 15:00).