Our mission is to become a worldwide reference for education in the field for all professionals involved in the process to disseminate knowledge & skills of Acute Cardiovascular Care.
Our mission is to promote excellence in clinical diagnosis, research, technical development, and education in cardiovascular imaging in Europe.
Our mission is to promote excellence in research, practice, education and policy in cardiovascular health, primary and secondary prevention.
Our mission is to reduce the burden of cardiovascular disease in Europe through percutaneous cardiovascular interventions.
Our mission is to improve the quality of life of the population by reducing the impact of cardiac rhythm disturbances and reduce sudden cardiac death.
Our mission is to improve quality of life and longevity, through better prevention, diagnosis and treatment of heart failure, including the establishment of networks for its management, education and research.
The ESC Working Groups' goal is to stimulate and disseminate scientific knowledge in different fields of cardiology.
The ESC Councils' goal is to share knowledge among medical professionals practising in specific cardiology domains.
OUR MISSION: TO REDUCE THE BURDEN OF CARDIOVASCULAR DISEASE
Stockholm, Sweden, 30 August: Through the use of virtual histology intravascular ultrasound (VH IVUS) and coronary computed tomography angiography (CTA) imaging techniques, research has demonstrated that the more dangerous plaques leading to coronary events tend to be located in the proximal part of the coronary arteries. This offers the promise that these lesions should be more accessible to local treatment options and more easily detected by non-invasive CTA.
At the Leiden University Medical Center, 168 patients reporting chest pain were evaluated by VH IVUS and CTA techniques. The purpose of the study was to gain more knowledge on the location of plaques in the coronary arteries. The researchers demonstrated that the more dangerous types of plaque were primarily located in the left anterior descending coronary artery (left coronary artery), particularly in the proximal part of the artery. Research lead, Doctor J. E. van Velzen of the Department of Cardiology at Leiden University Medical Center, summarised the results by noting that, “These findings strengthen the theory that the more dangerous plaques are located in particular regions. Also, plaques that are located proximally are more accessible to local invasive imaging techniques that aid identification, and to local treatment options such as percutaneous coronary intervention.”
Plaques have long been accepted as a contributory factor in coronary events. The rupture of a high-risk plaque, leading to an occlusion of a coronary artery, can result in a heart attack and even sudden cardiac death. Prior to this study, however, most data concerning the natural history and location of potentially high-risk plaques had been derived from retrospective autopsy studies. Interestingly, these studies demonstrated that the culprit lesions responsible for heart attacks are not uniformly distributed throughout the coronary artery tree, and tend to cluster within the proximal parts of the coronary arteries.
Two state-of-the-art imaging techniques were employed in this study to analyse the location of high-risk plaques. VH IVUS is an invasive catheter-based system that allows physicians to acquire images of diseased vessels from inside the artery. CTA, on the other hand, is non-invasive and has been demonstrated as a promising tool for assessment of coronary atherosclerotic plaques. Both techniques gave similar results and showed that almost half of high-risk plaques were located in the left anterior descending coronary artery and particularly in the proximal parts of the coronary arteries. However, high-risk plaque features were more uniformly distributed in the right coronary artery. The findings therefore support the theory that high-risk plaques have a focal location in the coronary artery tree and tend to be located in “hot spots”.
Reflecting on the study, Doctor van Velzen stated, “The results of this study are particularly relevant in the clinical setting, as they show how larger and more proximally located plaques can be easily detected by both invasive and non-invasive imaging techniques.”
Funding: Netherlands Heart Foundation (The Hague, Netherlands)
Contributors: Joëlla E. van Velzena,b, Joanne D. Schuijfa, Fleur R. de Graafa, Gabija Pundziutea, Fabrizio Spanóa, Martin J. Schalija, Lucia J. Kroftc, Albert de Roosc, Johannes H.C. Reiberc, J. Wouter Jukemaa,b, Ernst E. van der Walla,b, Jeroen J. Baxa (aDepartment of Cardiology, Leiden University Medical Center, Leiden, the Netherlands, bThe Inter-university Cardiology Institute of the Netherlands, Utrecht, the Netherlands, cDepartment of Radiology, Leiden University Medical Center, Leiden, the Netherlands)
This press release accompanies both a presentation and an ESC press conference given at the ESC Congress 2010. The press release has been written and/or edited by the ESC from information provided by the investigator and does not necessarily reflect the opinion of the European Society of Cardiology. The content of the press release has been approved by the investigator.
About the European Society of Cardiology The European Society of Cardiology (ESC) represents more than 62,000 cardiology professionals across Europe and the Mediterranean. Its mission is to reduce the burden of cardiovascular disease in Europe.
About ESC Congress 2010 ESC Congress 2010 will take place from 28 August to 1 September at the Stockholmsmässan, Stockholm. Information on the scientific programme is available at http://spo.escardio.org/Search.aspx?eevtid=40 More information on ESC Congress 2010 is available from the ESC's press office at firstname.lastname@example.org.
© 2017 European Society of Cardiology. All rights reserved