“The findings suggest that adding alirocumab to established statin regimens may provide an important new option to achieve needed reductions in low-density lipoprotein cholesterol (LDL-C) levels in high risk patients," said the study’s principal investigator, Christopher Cannon, MD, from the Harvard Clinical Research Institute in Boston, Massachusetts, USA.
“This trial evaluated a 75 mg initial dose of alirocumab, which could be increased to 150 mg if needed,” noted Dr. Cannon. “However, more than three-quarters of patients were able to reach target LDL-C levels at the initial dose without the need to up-titrate.”
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