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Barcelona, Spain – 28 Aug 2017: A 16 year study in more than 280 000 patients has suggested that air temperature is an external trigger for heart attack. The findings are presented today at ESC Congress. (1)“There is seasonal variation in the occurrence of heart attack, with incidence declining in summer and peaking in winter,” said first author Dr Moman A. Mohammad, from the Department of Cardiology at Lund University, Skane University Hospital, Lund, Sweden. “It is unclear whether this is due to colder temperatures or behavioural changes.”This nationwide, 16 year, observational study led by Prof David Erlinge from Lund University, is the largest to investigate the association between heart attack incidence and weather conditions such as air temperature, sunshine duration, precipitation, and air pressure.Using the Swedish myocardial infarction registry (SWEDEHEART), all consecutive heart attacks treated at a coronary care unit between 1 January 1998 and 31 December 2013 were included in the study. The investigators studied the specific weather conditions during which heart attacks occurred using local meteorological data from hundreds of weather stations in the Swedish Meteorological and Hydrological Institute (SMHI). The average daily minimum temperature was calculated for the entire country as well as the six healthcare regions in Sweden and stratified as <0 °C, 1–10 °C and >10 °C. The relationship between the average number of heart attacks per day and the average minimum air temperature was evaluated.During the study period, a total of 280 873 heart attacks occurred of which meteorological data were available for 99%. The average number of heart attacks per day was significantly higher during colder temperatures as compared to warmer. The results were consistent across healthcare regions.On a day-to-day basis, this translated into four more heart attacks in Sweden when the average daily temperature was less than 0 °C as compared to when it was above 10°C. Furthermore, the occurrence of heart attacks was increased with higher wind velocities, limited sunshine duration and higher air humidity. Consistent results were observed in ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction. The investigators analysed the relationship between heart attack incidence and weather conditions in subgroups including the elderly, those with hypertension, diabetes mellitus or previous heart attacks, and patients taking various medications. The link between heart attack incidence and weather conditions was stable across subgroups.Dr Mohammad said: “Our results consistently showed a higher occurrence of heart attacks in sub-zero temperatures. The findings were the same across a large range of patient subgroups, and at national as well as regional levels, suggesting that air temperature is a trigger for heart attack.”The body responds to cold by constricting superficial blood vessels, which decreases thermal conduction in the skin and subsequently increases arterial blood pressure. Other responses are shivering and increased heart rate, which raise the metabolic rate and in turn increase body temperature. “In the majority of healthy people these mechanisms are well tolerated,” said Dr Mohammad. “But in people with atherosclerotic plaques in their coronary arteries they may trigger a heart attack.”As this was an observational study, Dr Mohammad said there were other factors that may have contributed to the results. He said: “Respiratory tract infections and influenza are known risk factors for heart attack that have a clear seasonal variation. In addition, seasonal-dependent behaviours such as reduced physical activity and dietary changes could play a role in the increased occurrence of heart attack during colder weather.”ENDS
Sources of funding: The study was sponsored by The Swedish Heart and Lung Foundation, Swedish Scientific Research Council, SSF (TOTAL-AMI), Knut and Alice Wallenbergs Foundation, ALF and Skane University Hospital funds.
References and notes(1) The abstract “Air temperature as an external trigger of ST-segment elevation myocardial infarction - a SWEDEHEART nationwide observational study” will be presented during:· The session Impact of climate, air pollution and stress on acute coronary syndromes on Monday 28 August from 08:30 to 10:00 in Tripoli – Village 8.ESC Press OfficeFor more information, please contact the ESC Press Office: firstname.lastname@example.org.For press enquiries, independent comment on-site, please contact, the Media & Press Coordinator Jacques Olivier COSTA: +34 666 509 856The press conference timetable is available here.
To access all the scientific resources from the sessions during the congress, visit ESC Congress 365. About the European Society of CardiologyThe European Society of Cardiology brings together health care professionals from more than 140 countries, working to advance cardiovascular medicine and help people lead longer, healthier lives.About ESC Congress 2017ESC Congress is the world’s largest and most influential cardiovascular event contributing to global awareness of the latest clinical trials and breakthrough discoveries. ESC Congress 2017 takes place 26 to 30 August at the Fira Gran Via in Barcelona, Spain. The scientific programme is here. More information is available from the ESC Press Office at email@example.com.This press release accompanies a presentation at ESC Congress 2017. It does not necessarily reflect the opinion of the European Society of Cardiology.
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