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Atrial Fibrillation & Arrhythmia

Guest Editor: Prof. Steffel Jan, FESC, University Hospital Zurich

Atrial Fibrillation
Arrhythmias and Device Therapy


In this issue of the ESC Virtual Journal, we celebrate the latest EHRA Europace 2017 meeting last June in Vienna. Our guest editor, Professor Steffel Jan, has highlighted a selection of the must-see articles on Arrhythmia & Atrial Fibrillation from across the ESC Journal Family.

We have made these free to view in full-text format, so you can fully benefit from the science we publish.

VJ7--highlight-1.jpgThe Year in Cardiology 2016: arrhythmias and cardiac implantable electronic devices.

Cappato R, Hindricks G, Steffel J. Eur Heart J (2017) 38 (4): 238-246.

highlight-2.jpgDuration of device-detected subclinical atrial fibrillation and occurrence of stroke in ASSERT

Isabelle C. Van Gelder, Jeff S. Healey, Harry J.G.M. Crijns, Jia Wang, Stefan H. Hohnloser, Michael R. Gold, Alessandro Capucci, Chu-Pak Lau, Carlos A. Morillo, Anne H. Hobbelt, Michiel Rienstra, Stuart J. Connolly. Eur Heart J (2017) 38 (17): 1339-1344

VJ7-highlight-4.jpgArrhythmogenic right ventricular cardiomyopathy, clinical manifestations, and diagnosis.

Kristina H. Haugaa, Trine F. Haland, Ida S. Leren, Jørg Saberniak, Thor Edvardsen. Europace (2016) 18 (7): 965-972.



A roadmap to improve the quality of atrial fibrillation management: proceedings from the fifth Atrial Fibrillation Network/European Heart Rhythm Association consensus; Kirchhof et al ; DOI:10.1093/europace/euv304

Emerging risk factors and the dose-response relationship between physical activity and lone atrial fibrillation: a prospective case-control study; Calvo, Naiara; Ramos, Pablo; Montserrat, Silvia; Guasch, Eduard; Coll-Vinent, Blanca; Domenech, Monica; Bisbal, Felipe; Hevia, Sara; Vidorreta, Silvia; Borras, Roger; Falces, Carles; Embid, Cristina; Maria Montserrat, Josep; Berruezo, Antonio; Coca, Antonio; Sitges, Marta; Brugada, Josep; Mont, Lluis; DOI: 10.1093/europace/euv216

Anticoagulation reversal in the era of the non-vitamin K oral anticoagulants; Enriquez, Andres; Lip, Gregory Y. H.; Baranchuk, Adrian; DOI: 10.1093/europace/euv030

Real-world persistence and adherence to oral anticoagulation for stroke risk reduction in patients with atrial fibrillation; Beyer-Westendorf, Jan; Ehlken, Birgit; Evers, Thomas ; DOI: 10.1093/europace/euv421

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS; Kirchhof, et al ; DOI: 10.1093/europace/euw295

First-line catheter ablation of paroxysmal atrial fibrillation: outcome of radiofrequency vs. cryoballoon pulmonary vein isolation ; Straube, Florian; Dorwarth, Uwe; Ammar-Busch, Sonia; Peter, Timo; Noelker, Georg; Massa, Thomas; Kuniss, Malte; Ewertsen, Niels Christian; Chun, Kyoung Ryul Julian; DOI:10.1093/europace/euv271

One-year clinical outcome after pulmonary vein isolation in persistent atrial fibrillation using the second-generation 28 mm cryoballoon: a retrospective analysis ; Lemes, Christine; Wissner, Erik; Lin, Tina; Mathew, Shibu; Deiss, Sebastian; Rillig, Andreas; Heeger, Christian; Wohlmuth, Peter; Reissmann, Bruno; Tilz, Roland; Ouyang, Feifan; Kuck, Karl-Heinz; Metzner, Andreas; DOI:10.1093/europace/euv092

Effect of caffeine on ventricular arrhythmia: a systematic review and meta-analysis of experimental and clinical studies ; Zuchinali, Priccila; Ribeiro, Paula A. B.; Pimentel, Mauricio; da Rosa, Priscila R.; Zimerman, Leandro I.; Rohde, Luis E; DOI: 10.1093/europace/euv261

European Heart Rhythm Association/Heart Failure Association joint consensus document on arrhythmias in heart failure, endorsed by the Heart Rhythm Society and the Asia Pacific Heart Rhythm Society; Lip, Gregory Y. H.; Heinzel, Frank R.; Gaita, Fiorenzo; Gonzalez Juanatey, Jose Ramon; Le Heuzey, Jean Yves; Potpara, Tatjana; Svendsen, Jesper Hastrup; Vos, Marc A.; Anker, Stefan D.; Coats, Andrew J.; Haverkamp, Wilhelm; Manolis, Antonis S.; Chung, Mina K.; Sanders, Prashanthan; Pieske, Burkert ; DOI: 10.1093/europace/euv191

Arrhythmogenic right ventricular cardiomyopathy, clinical manifestations, and diagnosis
Haugaa, Kristina H.; Haland, Trine F.; Leren, Ida S.; Saberniak, Jorg; Edvardsen, Thor;  DOI: 10.1093/europace/euv340

Global left atrial failure in heart failure
Triposkiadis F, Pieske B, Butler J, Parissis J, Giamouzis G, Skoularigis J,Brutsaert D, Boudoulas H ; DOI: 10.1002/ejhf.645

Severity of renal impairment in patients with heart failure and atrial fibrillation: implications for non-vitamin K antagonist oral anticoagulant dose adjustment
Hawkins NM, Jhund PS, Pozzi A, O'Meara E, Solomon SD, Granger CB, Yusuf S,Pfeffer MA, Swedberg K, Petrie MC, Virani S, McMurray J; DOI: 10.1002/ejhf.614

Efficacy and safety of edoxaban compared with warfarin in patients with atrial fibrillation and heart failure: insights from ENGAGE AF-TIMI 48
Magnani G, Giugliano RP, Ruff CT, Murphy SA, Nordio F, Metra M, Moccetti T, Mitrovic V, Shi M, Mercuri M, Antman EM, Braunwald E; DOI: 10.1002/ejhf.595

Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC). Is heart rate a risk marker in patients with chronic heart failure and concomitant atrial fibrillation? Results from the MAGGIC meta-analysis
Simpson J, Castagno D, Doughty RN, Poppe KK, Earle N, Squire I, Richards M, Andersson B, Ezekowitz JA, Komajda M, Petrie MC, McAlister FA, Gamble GD, Whalley GA, McMurray JJ; DOI: 10.1002/ejhf.346

Non-vitamin K antagonist oral anticoagulants (NOACs) in patients with concomitant atrial fibrillation and heart failure: a systemic review and meta-analysis of randomized trials
Xiong Q, Lau YC, Senoo K, Lane DA, Hong K, Lip GY; DOI: 10.1002/ejhf.343

Hypertension and Cardiac Arrhythmias: Executive Summary of a Consensus Document from the European Heart Rhythm Association (EHRA) and ESC Council on Hypertension, endorsed by the Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS) and Sociedad Latinoamericana de Estimulación Cardíaca y Electrofisiología (SOLEACE)
Lip GYH, Coca A, Kahan T, Boriani G, Manolis AS, Olsen MH, Oto A, Potpara TS, Steffel J, Marín F, de Oliveira Figueiredo MJ, de Simone G, Tzou WS, Chiang CE, Williams B; Eur Heart J Cardiovasc Pharmacother pvw044

Multi-morbidity, frailty and self-care: important considerations in treatment with anticoagulation drugs. Outcomes of the AFASTER study
Ferguson C, Inglis SC, Newton PJ, Middleton S, Macdonald PS, Davidson PM; European Journal of Cardiovascular Nursing 2017, Vol 16, Issue 2

Alcohol consumption, sinus tachycardia, and cardiac arrhythmias at the Munich Octoberfest: results from the Munich Beer Related Electrocardiogram Workup Study (MunichBREW).
Brunner S, Herbel R, Drobesch C, Peters A, Massberg S, Kääb S, Sinner MF; Eur Heart J ehx156

Electrical cardiac injuries: current concepts and management.
Waldmann V, Narayanan K, Combes N, Jost D, Jouven X, Marijon E; Eur Heart J ehx142.

Long-term symptom improvement and patient satisfaction following catheter ablation of supraventricular tachycardia: insights from the German ablation registry
Brachmann J, Lewalter T, Kuck KH, Andresen D, Willems S, Spitzer SG, Straube F, Schumacher B, Eckardt L, Danilovic D,  Thomas D, Hochadel M, Senges J; Eur Heart J (2017) 38 (17): 1317-1326

Avoiding non-responders to cardiac resynchronization therapy: a practical guide.
Daubert C, Behar N, Martins RP, Mabo P, Leclercq C; Eur Heart J (2017) 38 (19): 1463-1472.

Magnetic resonance imaging of atrial fibrosis: redefining atrial fibrillation to a syndrome.
Gal P, Marrouche NF; Eur Heart J (2017) 38 (1): 14-19.

The Year in Cardiology 2016: arrhythmias and cardiac implantable electronic devices.
Cappato R, Hindricks G, Steffel J; Eur Heart J (2017) 38 (4): 238-246.

A score model to predict risk of events in patients with Brugada Syndrome.
Sieira J, Conte G, Ciconte G, Chierchia GB, Casado-Arroyo R, Baltogiannis G, Di Giovanni G, Saitoh Y, Juliá J, Mugnai G, La Meir M, Wellens F, Czapla J, Pappaert G, de Asmundis C, Brugada P; Eur Heart J (2017) 38 (22): 1756-1763.

Implantable cardioverter defibrillators for primary prevention of death in left ventricular dysfunction with and without ischaemic heart disease: a meta-analysis of 8567 patients in the 11 trials.
Shun-Shin MJ, Zheng SL, Cole GD, Howard JP, Whinnett ZI, Francis DP; Eur Heart J (2017) 38 (22): 1738-1746

Remote management of heart failure using implantable electronic devices.
Morgan JM, Kitt S, Gill J, McComb JM, Ng GA, Raftery J, Roderick P, Seed A, Williams SG, Witte KK, Wright DJ, Harris S, Cowie MR; Eur Heart J ehx227.

Catheter ablation of supraventricular tachycardias: where we have been, where we are, and where we are going
Zipes DP; Eur Heart J (2017) 38 (17): 1327-1328.

Duration of device-detected subclinical atrial fibrillation and occurrence of stroke in ASSERT
Van Gelder IC, Healey JS, Crijns HJGM, Wang J, Hohnloser SH, Gold MR, Capucci A, Lau CP, Morillo CA, Hobbelt AH, Rienstra M, Connolly SJ; Eur Heart J (2017) 38 (17): 1339-1344.

Contemporary management of patients undergoing atrial fibrillation ablation: in-hospital and 1-year follow-up findings from the ESC-EHRA atrial fibrillation ablation long-term registry.
Arbelo E, Brugada J, Blomström-Lundqvist C, Laroche C, Kautzner J, Pokushalov E, Raatikainen P, Efremidis M, Hindricks G, Barrera A, Maggioni A, Tavazzi L, Dagres N; on the behalf of the ESC-EHRA Atrial Fibrillation Ablation Long-term Registry Investigators; Eur Heart J (2017) 38 (17): 1303-1316

The European Lead Extraction ConTRolled (ELECTRa) study: a European Heart Rhythm Association (EHRA) Registry of Transvenous Lead Extraction Outcomes.
Bongiorni MG, Kennergren C, Butter C, Deharo JC, Kutarski A, Rinaldi CA, Romano SL, Maggioni AP, Andarala M, Auricchio A, Kuck KH, Blomström-Lundqvist C; , on behalf of ELECTRa Investigators;  Eur Heart J ehx080.

Arrhythmogenic anatomical isthmuses identified by electroanatomical mapping are the substrate for ventricular tachycardia in repaired Tetralogy of Fallot
Kapel GF, Sacher F, Dekkers OM, Watanabe M, Blom NA, Thambo JB, Derval N, Schalij MJ, Jalal Z, Wijnmaalen AP, Zeppenfeld K; Eur Heart J (2017) 38 (4): 268-276.

The subcutaneous implantable cardioverter defibrillator: state-of-the-art review
McLeod CJ, Boersma L, Okamura H, Friedman PA; Eur Heart J (2017) 38 (4): 247-257

European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulación Cardiaca y Electrofisiologia (SOLAECE)
Katritsis DG, Boriani G, Cosio FG, Hindricks G, Jais P, Josephson ME, Keegan R, Kim YH, Knight BP, Kuck KH, Lane DA, Lip GY, Malmborg H, Oral H, Pappone C, Themistoclakis S, Wood KA, Blomström-Lundqvist C;  Eur Heart J ehw455.

Screening for atrial fibrillation during influenza vaccinations by primary care nurses using a smartphone electrocardiograph (iECG): A feasibility study.
Orchard J,2, Lowres N, Freedman SB, Ladak L, Lee W, Zwar N, Peiris D, Kamaladasa Y, Li Z, Neubeck L; European Journal of Preventive Cardiology 2016,Vol 23, Issue 2_suppl, 2016

European Heart Rhythm Association (EHRA)/European Association of Cardiovascular Prevention and Rehabilitation (EACPR) position paper on how to prevent atrial fibrillation endorsed by the Heart Rhythm Society (HRS) and Asia Pacific Heart Rhythm Society (APHRS).
Gorenek Chair B, Pelliccia Co-Chair A, Benjamin EJ, Boriani G, Crijns HJ, Fogel RI, Van Gelder IC, Halle M, Kudaiberdieva G, Lane DA, Bjerregaard Larsen T, Lip GY, L¿chen ML, Marin F, Niebauer J, Sanders P, Tokgozoglu L, Vos MA, Van Wagoner DR; Document reviewers:, Fauchier L, Savelieva I, Goette A, Agewall S, Chiang CE, Figueiredo M, Stiles M, Dickfeld T, Patton K, Piepoli M, Corra U, Manuel Marques-Vidal P, Faggiano P, Schmid JP, Abreu A; European Journal of Preventive Cardiology 2016, Vol 24, Issue 1, 2017

Patient-derived models link re-entrant driver localization in atrial fibrillation to fibrosis spatial pattern
Sohail Zahid, Hubert Cochet,  Patrick M. Boyle, Erica L. Schwarz, Kaitlyn N. Whyte, Edward J. Vigmond, Rémi Dubois, Mélèze Hocini, Michel Haïssaguerre, Pierre Jaïs, Natalia A; Trayanova. Cardiovasc Res (2016) 110 (3): 443-454.

The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis
Jordi Heijman, Vincent Algalarrondo, Niels Voigt, Jonathan Melka, Xander H.T. Wehrens, Dobromir Dobrev, Stanley Nattel; Cardiovasc Res (2016) 109 (4): 467-479