Dr. Ruxandra Jurcut,
A pregnant women and fetus or lactating mother and baby in general are at increased risk of being impacted by disease and the effects of medication. Specifically, presence of thromboembolic disease and/or specific thrombophilia (i.e. antiphospholipid syndrome) or a mechanical prosthesis may warrant the use of anticoagulation. Definite knowledge of anticoagulation in these situations is warranted.
Interesting link: ESC guidelines on cardiovascular diseases during pregnancy.
1)Venous Thromboembolism in Pregnancy. James HA. Arterioscler Thromb Vasc Biol 2009; 29;326-3312)Pregnancy-related mortality in the United States, 1998 to 2005. Berg CJ, Callaghan WM, Syverson C, Henderson Z. Obstet Gynecol. 2010 Dec;116(6):1302-93)Anticoagulants and pregnancy: When are they safe?Gibson PS, Powrie R. Cleve Clin J Med. 2009;76(2):113-274)Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (9th edition).Bates S, Greer I, Middeldorp D et al. Chest. 2012; 141(2)(Suppl):e691S–e736S5)ESC Guidelines on the management of cardiovascular diseases during pregnancy.Regitz-Zagrosek V, Blomstrom Lundqvist V, Borghi C et al. Eur Heart J. 2011;32(24):3147-97
Ruxandra Jurcut MD, PhD, FESCUniversity of Medicine and Pharmacy “Carol Davila” – Department of CardiologyInstitute of Emergency for Cardiovascular Diseases “Prof.dr.C.C.Iliescu”Bucharest, RomaniaAuthor's disclosures: none declared.
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