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Basic science summer school

Add to calendar18/06/20170:00 22/06/20170:00 Europe/Paris Basic science summer school

Organised by the Council on Basic Science: Inspire a new generation of basic cardiovascular science leaders taken from among the most gifted science and medical graduates - Provide opportunities to meet face-to-face role models from an expert faculty of successful cardiovascular scientists.

Council on Basic Cardiovascular Science contact@escardio.org true DD/MM/YYYY
Basic Sciences, Pharmacology, Genomics and Cardiovascular Pathology
In-person
event

Summary

Organised by the Council on Basic Science: Inspire a new generation of basic cardiovascular science leaders taken from among the most gifted science and medical graduates - Provide opportunities to meet face-to-face role models from an expert faculty of successful cardiovascular scientists.

Focus on

Course objectives

  • Inspire a new generation of cardiovascular science leaders taken from among the most gifted science and medical graduates
  • Provide opportunities to meet face-to-face with individual members of the expert faculty of successful cardiovascular scientists
  • Provide opportunities to meet face-to-face with representatives from industry and understand better how scientific discovery can be translated into patient benefit
  • Give examples of how cardiovascular science has advanced in key areas and has impacted on clinical practice
  • Identify major challenges for the next generation
  • Impart insights into those theoretical aspects of pathophysiology, pharmacology, molecular biology and genomics of cardiacS and vascular diseases necessary to underpin a selection of future challenges
  • Open up a broader perspective on the issues necessary for implementation of research findings in medical practice
  • Increase confidence among young scientists as investigators and communicators
  • Promote networking between young scientists throughout Europe


Who is the Summer School for?

Mainly early stage researchers (PhD and MD/PhD students in the first three years of their research) plus a few more experienced researchers whose PhD degree was obtained within the last 2 years. Delegate numbers limited to 70.

All delegates bring a poster of their research, which is on display throughout the Summer School programme.

Course directors

Giuseppina Caligiuri (FR), Jolanda van der Velden (NL), Jérémy Fauconnier (FR) and Gemma Vilahur (ES) representing the Scientists of Tomorrow

Scientific programme by day

Sunday 18 June - Novotel Nice Arenas

18:00          Welcome – Course Directors
18:15          Opening keynote plenary lecture (Chair : Peter Ferdinandy)
                   Jörg Menche (Vienna - Austria)
                   Network modelling and analysis in cardiovascular disease

19:15          Cocktail dinner

Monday 19 June - European Heart House

Session 1:  Cardioprotection (Chair : Jeremy Fauconnier)
09:00          Key pathways to ischemia-reperfusion injury
                   Sean Davidson (London - United Kingdom)
09:45          Opportunities and challenges in translating cardioprotection to the clinic
                   Gemma Vilahur (Barcelona - Spain)

10:30          Coffee break – poster area

Session 2:   Cardiac and vascular development (Chair : Giuseppina Caliguri)
11:00          Cardiac development: insights into congenital heart disease
                   Adriana Gittenburger-de Groot (Leiden, NL) 
11.45          Origins of vascular smooth muscle cells and implications for disease
                   Sanjay Sinha (Cambridge, United Kingdom)

12:30           Lunch Boxes – Poster Area-  Meet the faculty


Session 3:  Thrombosis and coagulation (Chair : Jeremy Pearson)
13:30          Control of thrombosis and fibrinolysis in vivo: implications for new therapies
                   Nicola Mutch (Aberdeen, United Kingdom)
14:15          Novel oral anticoagulants: mechanisms of action and therapeutic indications
                   Raffaele de Caterina (Chieti, Italy)

15:00           Short break

Session 4:   Publishing your research (Chair : Peter Ferdinandy)
15.15           Getting the experimental design and statistical analysis right 
                    Dirk Duncker (Rotterdam)
16.00           Writing the paper: what the journal editors expect
                    Karin Sipido (Leuven, Belgium; Editor in Chief, Cardiovascular Research) 

17.00-18.30 Refreshments - Poster area –  Meet the faculty and exhibitors

Tuesday 20 June

Session 5:   Novel methods to measure and control cardiomyocyte function (Chair: Jolanda van der Velden)
09.00          Measuring the physiological responses of single cardiomyocytes
                   Michiel Helmes (Ionoptix)
09.45          Optogenetic control of cardiac rhythm
                   Claudia Richter (Göttingen, Germany)
           
10.30          Coffee Break – poster area

Session 6:    The immune response and atherogenesis (Chair : Jeremy Pearson)
11.00           The roles of T and B cells
                    Giuseppina Caligiuri (Paris, France)
11.45           Targeting immune receptors to reduce atherosclerosis
                    Norbert Gerdes (Düsseldorf, Germany)

12.30            Lunch Boxes – Poster area -  Meet the faculty

Session 7:     Regenerative medicine (Chair : Gemma Vilahur)
13.30            Therapeutic angiogenesis: the long road to translation
                     Seppo Ylä-Herttuala (Kuopio, Finland)                  
14.15            Bioengineered grafts for the infarcted heart
                     Antoni Bayés Genis (Barcelona, Spain) 

15.00            Short break

Session 8:     How and why pharma and academia collaborate to develop new medicines (Chair: Jeremy Fauconnier)
15.15            Role of academic research and spin-off (start-up) companies in drug development
                     Peter Ferdinandy (Budapest, Hungary)
15.50            How Big Pharma and academia collaborate
                     
Patricia Sansilvestri-Morel (Suresnes, France)
16.20            Development of advanced therapy medicinal products: need for collaborations with academia and                                specialized R&D companies
                     Swetlana Adamsky (Tel-Aviv, Israel)

16:50             Short Break

17.00-18.30  Poster area – discussion of even-numbered posters, with refreshments

Wednesday 21 June

Session 9:   Cardiac contractile dysfunction (Chair : Jolanda van der Velden)
09.00          Cardiometabolic dysregulation, mitochondrial function and arrhythmia
                   Jérémy Fauconnier (Montpellier, France)
09.45          Cardiomyopathies: biology and future treatment options
                   Jolanda van der Velden (Amsterdam, Netherlands)

10.30           Coffee Break – poster area

Session 10:  Non-coding RNAs (Chair : Giuseppina Caliguri)
11:00          Control of cardiac remodelling and fibrosis by ncRNAs
                   Paula da Costa Martins (Maastricht, NL) 
11:45          Control of angiogenesis and arteriogenesis by miRNAs
                   Yaël Nossent (Leiden, Netherlands)

12:30           Lunch Boxes – Poster area - Meet the faculty


Session 11:   Vulnerable Plaque ( Chair: jeremy Perason)
13:30           The vulnerable plaque – an evolving target?
                    Gerard Pasterkamp (Utrecht, Netherlands)
14:15            Imaging the vulnerable plaque to stratify individual patient risk
                    Marc Dweck (Edinburgh, United Kingdom)

15:00            Short break  

Session 12:  Finding new drug targets: the worlds of informatics and omics (Chair : Peter Ferdinandy)
15.15           The advantages and limitations of proteomics and metabolomics
                    Manuel Mayr (London, United Kingdom)
15.45           Using Mendelian randomization to impute causality in genomic studies
                    Jemma Hopewell (Oxford, United Kingdom)

17.00-18.30   Poster area – discussion of odd-numbered posters, with refreshments

20.30           Participants dinner (Beach party!)

Thursday 22 June

Session 13:   Building your career 
09.00           Advice from the faculty and open discussion

10.00           Coffee Break

Session 14:  iPS cells and personalised medicine (Chair : Gemma Vilahur)
10.30           iPS cell-derived cardiomyocytes for drug testing
                    Daniel Sinnecker (Munich, DE)
11.15           iPS cell-derived cardiomyocytes: directing phenotype for therapeutic use
                    Chris George (Swansea, UK)          
12.00          Closing keynote plenary lecture (Chair : Jeremy Pearson)
                   Healthy cardiovascular aging: the life course perspective
                   Mark Hanson (Southampton, UK)                    


Discover more about the ESC Council on Basic Cardiovascular Science

Selection process

Pre-registration is now closed

The selection process has started and if you are selected, we will inform you and send you a link to finalise your registration and payment (by mid-march).

The Summer School 2017 has a limited number of places. If you are accepted, your registration will be considered when payment of 300 Euros is made to the ESC.

Registration

Fees for students: 300 Euros (the fee covers course registration, accommodation and breakfast, lunches, 2 evening meals, transport to and from Nice airport and transport between the Novotel Arenas and the European Heart House).

Extras: students will be expected to pay for their flights to Nice Airport and any items not covered in the list above.

Course venue

The European Heart House 
Les Templiers
2035 Routes des Colles
CS 80179 Biot
06903 Sophia Antipolis Cedex, France

Course Organisers

Jeremy Pearson (UK)

Peter Ferdinandy (HU)