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What’s new from the EACVI Research and Innovations committee?

Imaging


Dr. Julien Magne.jpg

Dr. Julien Magne

Since its inception under the presidency of Professor Patrizio Lancellotti and leadership by Professor Erwan Donal, EACVI’s Research and Innovations (R&I) committee has quickly evolved and grown in impact and scope.

From 2013 to 2016, many projects were successfully launched and interesting results continue to be published from these studies, including the large multicentre Euro-Filling and NORRE registries. Since 2016, the R&I committee has been chaired by Doctor Julien Magne (CHU Limoges, Limoges, France) and he discussed recent progress and projects.

“We are finalising and building on the results of previously initiated studies as well as launching new projects and extending the initial roadmap.”

“One of our latest achievements is an individual-participant data meta-analysis on left ventricular global longitudinal strain (LVGLS) in asymptomatic significant aortic stenosis, which has just been accepted for publication in JACC: Cardiovascular Imaging. Our objectives were to describe its distribution, identify the most predictive cut-off values and assess its impact on mortality. This work has taken around 4 years to complete but we feel it will really add to the knowledge of the usefulness of LVGLS in the management and risk stratification of these patients.”

Dr. Magne continued, “In the last 2 years, we have also launched two major studies in atrial fibrillation (AF) and on the left atrial function. One of these projects is an exciting collaboration with our Heart Imagers of Tomorrow (HIT). Led by Dr. Matteo Cameli, Chair of (HIT) committee, the large multicentre MASCOT study aims to assess the best imaging parameters to evaluate the function of the left atrium. This is a very important project since, for the first time, the EACVI R&I committee has supported a largescale project where the majority of investigators have come from the HIT committee. The project is progressing well and we hope to have the first results next year. In our eyes, this project is already a success though as it has been excellently managed by our very enthusiastic HIT committee.”

“In a project led by Prof. Maurizio Galderisi, with a strong contribution from Dr. Francesco Lo Iudice, we have also launched the EACVI AFib Echo Europe Registry. This observational, cross-sectional study has been designed to collect data on the echocardiographic phenotype of patients with any kind of AF in a panorama of reference European echo labs. The registry will evaluate the relationship between echocardiographic parameters of left atrial dimension and function, left ventricular geometry, left ventricular systolic and diastolic function with clinical thromboembolic and bleeding risk profiles. We have published the rationale and design of the EACVI AFib Echo Europe Registry1 and completed the process of reproducibility assessments—the main body of the project will begin soon.”

Dr. Magne concluded, “The EACVI R&I committee have many other projects in the pipeline, more particularly regarding multi-modalities imaging and we look forward to seeing these projects mature and to presenting what we hope will be their valuable findings.”

 

  1. Galderisi M, et al. Eur Heart J Cardiovasc Imaging. 2018;19:245–252.