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Hypertrophic Cardiomyopathy

ESC Clinical Practice Guidelines

Topics: Myocardial Disease

30/08/2014 00:00:00

Current versions available to download

Publication dateVersionsReferencesSize
2014Full Textdoi/10.1093/eurheartj/ehu284
2014Essential Messages2014 Takes Home Messages & Gap in Evidence632 KB
2014 Summary CardSummary Card for General Practice on HCM323 KB
2014Related MaterialsWeb Addenda935 KB
2014Related MaterialsHCM online calculator

Authors

Perry M. Elliott (Chairperson) (UK) Aris Anastasakis (Greece), Michael A. Borger (Germany), Martin Borggrefe (Germany), FrancoCecchi (Italy), Philippe Charron (France), Albert Alain Hagege (France), Antoine Lafont (France),GiuseppeLimongelli (Italy),HeikoMahrholdt (Germany),WilliamJ.McKenna (UK), Jens Mogensen (Denmark), Petros Nihoyannopoulos (UK), Stefano Nistri (Italy),Petronella G. Pieper (Netherlands), Burkert Pieske (Austria), Claudio Rapezzi (Italy), Frans H. Rutten (Netherlands), Christoph Tillmanns (Germany), HughWatkins (UK)

Declarations of Interest of the experts involved in the elaboration of the document

Endorsed by:

Table of contents: Full Text (ESC Clinical Practice Guidelines)

Preamble

Introduction

            Definition

            Scope of Guidelines

Epidemiology

Aetiology

            Sarcomere protein gene mutations

            Metabolic disorders

            Mitochondrial cardiomyopathies

            Neuromuscular disease

            Malformation syndromes

            Infiltrative disease/inflammation

            Endocrine disorders

            Drugs

Diagnosis

            Diagnostic criteria

                        Adults

                        Children

                        Relatives

            History and physical examination

            Resting and ambulatory electrocardiography

            Echocardiography

                        Assessment of left ventricular wall thickness

                        Associated abnormalities of the mitral valve and left ventricular outflow tract

                        Assessment of latent obstruction

                        Left atrial enlargement

                        Assessment of diastolic function

                        Systolic function

                        Role of echocardiography in differential diagnosis

                        Contrast echocardiography

                        Transoesophageal echocardiography

            Cardiovascular magnetic resonance imaging

                        Assessment of ventricular morphology and function

                        Myocardial fibrosis

                        Role in prognosis

                        Differential diagnosis

            Nuclear imaging

            Endomyocardial biopsy

            Laboratory tests

Genetic testing and family screening

            Counselling in probands

            Methods for molecular genetic screening in probands

            Indications for genetic testing in probands

            Genetic and clinical screening of relatives

                        Families with definite genetic mutations

                        Families without definite genetic mutations

            Genetic and clinical screening of children

            Follow-up of mutation carriers without a phenotype

            Pre-implantation and pre-natal genetic testing

Delivery of care

            Education and training

Assessment of symptoms

            Chest pain

            Heart failure

                        Invasive pressure studies

                        Cardiopulmonary exercise testing

            Syncope

            Palpitations

            Role of electrophysiological testing

Management of symptoms and complications

Left ventricular outflow tract obstruction

                        General measures

                        Drug therapy

                        Invasive treatment of left ventricular outlow tract obstruction

            Mid-cavity obstruction and apical aneurysms

            Management of symptoms in patients without left ventricular outlow tract obstruction

                        Heart failure

                        Angina

            Atrial tachyarrhythmia

                        Acute treatment

            Sudden cardiac death

                        Clinical risk assessment

                        Models for estimating sudden cardiac death

                        Prevention of sudden cardiac death

                        Risk of sudden death in children

            Symptomatic bradycardia and atrioventricular block

            Ventricular tachycardia

Recommendations for routine follow-up

Reproduction and contraception

            Introduction

            Contraception and termination of pregnancy

            Infertility treatment

            Pre-conception counselling

            Management of pregnancy and delivery

Special issues

            Diagnosis of hypertrophic cardiomyopathy in athletes

            Hypertension

                        Imaging

                        Electrocardiogram

            Isolated basal septal hypertrophy (sigmoid septum) in elderly people

            Diagnosis and management of valve disease in patients with hypertrophic cardiomyopathy

                        Aortic valve disease

                        Mitral valve disease

                        Endocarditis prophylaxis

Living with cardiomyopathy: advice to patients

Appendix

References


Previous versions

Year Title Journal Issue
2003 Hypertrophic Cardiomyopathy Eur Heart J 24:1965–1991