Our mission is to become a worldwide reference for education in the field for all professionals involved in the process to dissemintate knowledge & skills of Acute Cardiovascular Care
Our mission is to promote excellence in clinical diagnosis, research, technical development, and education in cardiovascular imaging in Europe.
Our mission: To promote excellence in research, practice, education and policy in cardiovascular health, primary and secondary prevention.
Our goal is to reduce the burden in cardiovascular disease in Europe through percutaneous cardiovascular interventions.
Our Mission is "to improve the quality of life of the population by reducing the impact of cardiac rhythm disturbances and reduce sudden cardiac death"
To improve quality of life and logevity, through better prevention, diagnosis and treatment of heart failure, including the establishment of networks for its management, education and research.
Working Groups goals is to stimulate and disseminate scientific knowledge in different fields of cardiology.
ESC Councils goal is to share knowledge among medical professionals practising in specific cardiology domains.
OUR MISSION: TO REDUCE THE BURDEN OF CARDIOVASCULAR DISEASE
Dr. Nicolle Kraenkel
Dr. Paul Leeson,
1] Dynamic Release and Clearance of Circulating Microparticles During Cardiac Stress D. Augustine, L.V. Ayers, E. Lima, L. Newton, A.J. Lewandowski, E.F. Davis, B. Ferry, P. LeesonCirculation Research; doi: 10.1161/CIRCRESAHA.114.301904
2] Dynamic microvesicle release and clearance within the cardiovascular system: triggers and mechanismsL. Ayers, R. Nieuwland, M. Kohler, N. Kraenkel, B. Ferry, P. LeesonClin Sci (Lond). 2015. doi: 10.1042/CS20140623.
Several years ago small pieces of cells, called microvesicles (or microparticles), were observed within human blood. It was realised these were being actively released by cells into the circulation and may be acting as a means of communication between cells. There has been rapidly increasing interest ever since in whether these particles could be used for cardiovascular diagnostics or therapeutics.
Microvesicles have often been measured in the circulation at a single time point. However, several papers have now shown that microvesicle levels both increase and decrease rapidly in response to certain stimuli such as hypoxia, acute cardiac stress, shear stress, hypertriglyceridaemia and inflammation . Levels of circulating microvesicles therefore likely reflect a balance between dynamic mechanisms for release and clearance. Understanding what drives these changes may give new insights into how cells communicate and what this tells us about different disease states. A recently published collaborative review article  including members of the EBTR section of the EACPR has for the first time provided a detailed overview of these mechanisms. The information will help guide development of experiments that seek to identify potential underlying biological mechanisms that might drive increases or decreases in circulating microvesicle levels as well as help design future clinical studies.
Also of interest:
"How to measure microparticles in prevention and rehabilitation"Nicolle Kraenkel answers key questions on behalf of the Exercise, Basic and Translational Research Section
The content of this article reflects the personal opinion of the author/s and is not necessarily the official position of the European Society of Cardiology