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EACPR Basic Science Section Chairman

Rainer Hambrecht

Vision Statement l CV

“Since basic sience, i.e. molecular cardiology is not adaequately represented in the former working groups the major goal of this section will be to organize a network of basic researchers who are interested and/or already actively involved in scientific projects wich belongs to the major topics of the newly founded EACPR.
The main topics should focus on:

Applied Basic Research

  • exercise and endothelial function – signal cascades
  • inflammation/catabolism - pathomechanisms
  • exercise and left ventricular contractility - mechanisms
  • exercise capacity and genetics - SNPs

Basic Epidemiology

Aims of the network will be:

  • recruit qualified researchers in Europe
  • organize a platform for communication/interaction between groups
  • define committees and study groups for specific topics
  • organize meetings and symposia within the large ESC conferences
  • apply for financial support (grant application)

The section ‘Basic Research’ is open for everybody interested in pathophysiology and molecular research. First contacts to scientists in Norway, France, Great Britain, and Germany reveal a great interest to participate and to cooperate within the Section. Those groups which have been already contacted, have published landmark studies i.e. regarding the genetic background of aerobic exercise capacity in rats (Wisloff U. from Trondheim in Norway: Science 2005), exercise and Ca2+-handling/LV contractility in rats (Ellingsen from Trondheim in Norway: Circulation 2004), exercise and progenitor cells (Laufs from Homburg in Germany: Circulation 2004), exercise and oxidative stress (Adams from Leipzig in Germany: Circulation 2005), skeletal muscle metabolism (Ventura-Clapier, Paris, France), gene polymorphisms (L. Vanhees, Leuven, Belgium), and inflammation (V. Conraads, Belgium). Main issue for the next months after the spring meeting in Athens will be to identify 10 or more research teams (list of potential coop. teams is attached). Researches identified will be motivated to come to our next common meetings to discuss the newest research results within our association. During next months it will be the aim to develop clusters for specific topics, i.e. genetics, endothelial function etc. In a second step we have to discuss within the board of the EACPR and the leaders of the other sections whether we can collect a critical mass of top researchers and scientific questions/topics to apply for EU framework program and other grants.”