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Hypertrophic Cardiomyopathy

ESC Clinical Practice Guidelines

Congenital Heart Disease in Children and Adults
Myocardial Disease
Guidelines version available to download
Published in 2014
Reference Eur Heart J (2014) 35:2733-2779 - doi/10.1093/eurheartj/ehu284
Published in 2014
Reference Web Addenda
Published in 2014
Reference HCM online calculator
Published in 2014
Reference 36 CME Questions
Published in 2014
Reference 2014 Takes Home Messages & Gap in Evidence
Published in 2014
Reference Summary Card for General Practice on HCM
  • PDA
  • Published in 2014
    Reference HCM Pocket Guidelines Mobile App
    Published in 2014
    Reference Pocket Guidelines Abriged version
    Published in 2014
    Reference ESC-2014-Slide-set-Hypertrophic-Cardiomyopathy
    Table of contents: Full Text (ESC Clinical Practice Guidelines)




                Scope of Guidelines



                Sarcomere protein gene mutations

                Metabolic disorders

                Mitochondrial cardiomyopathies

                Neuromuscular disease

                Malformation syndromes

                Infiltrative disease/inflammation

                Endocrine disorders



                Diagnostic criteria




                History and physical examination

                Resting and ambulatory electrocardiography


                            Assessment of left ventricular wall thickness

                            Associated abnormalities of the mitral valve and left ventricular outflow tract

                            Assessment of latent obstruction

                            Left atrial enlargement

                            Assessment of diastolic function

                            Systolic function

                            Role of echocardiography in differential diagnosis

                            Contrast echocardiography

                            Transoesophageal echocardiography

                Cardiovascular magnetic resonance imaging

                            Assessment of ventricular morphology and function

                            Myocardial fibrosis

                            Role in prognosis

                            Differential diagnosis

                Nuclear imaging

                Endomyocardial biopsy

                Laboratory tests

    Genetic testing and family screening

                Counselling in probands

                Methods for molecular genetic screening in probands

                Indications for genetic testing in probands

                Genetic and clinical screening of relatives

                            Families with definite genetic mutations

                            Families without definite genetic mutations

                Genetic and clinical screening of children

                Follow-up of mutation carriers without a phenotype

                Pre-implantation and pre-natal genetic testing

    Delivery of care

                Education and training

    Assessment of symptoms

                Chest pain

                Heart failure

                            Invasive pressure studies

                            Cardiopulmonary exercise testing



                Role of electrophysiological testing

    Management of symptoms and complications

    Left ventricular outflow tract obstruction

                            General measures

                            Drug therapy

                            Invasive treatment of left ventricular outlow tract obstruction

                Mid-cavity obstruction and apical aneurysms

                Management of symptoms in patients without left ventricular outlow tract obstruction

                            Heart failure


                Atrial tachyarrhythmia

                            Acute treatment

                Sudden cardiac death

                            Clinical risk assessment

                            Models for estimating sudden cardiac death

                            Prevention of sudden cardiac death

                            Risk of sudden death in children

                Symptomatic bradycardia and atrioventricular block

                Ventricular tachycardia

    Recommendations for routine follow-up

    Reproduction and contraception


                Contraception and termination of pregnancy

                Infertility treatment

                Pre-conception counselling

                Management of pregnancy and delivery

    Special issues

                Diagnosis of hypertrophic cardiomyopathy in athletes




                Isolated basal septal hypertrophy (sigmoid septum) in elderly people

                Diagnosis and management of valve disease in patients with hypertrophic cardiomyopathy

                            Aortic valve disease

                            Mitral valve disease

                            Endocarditis prophylaxis

    Living with cardiomyopathy: advice to patients






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    European Society
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