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Diabetes, Pre-Diabetes and Cardiovascular Diseases developed with the EASD

ESC Clinical Practice Guidelines

Topics: Diabetic heart disease


The emphasis in these Guidelines is to provide information on the current state of the art in how to prevent and manage the diverse problems associated with the effects of DM on the heart and vasculature in a holistic manner.
31/08/2013 00:00:00

Current versions available to download

Publication dateVersionsReferencesSize
2013Essential Messages994 KB
2013 Summary Card440 KB
2013Full TextEur Heart J 2013;34:3035-3087
2014CorrigendumCorrigendum Diabetes
2007Executive SummaryEHJ 2007;28:88-1361 MB
2013Executive Summary2 MB
2013Pocket Guidelines
2013 Slide-setSlide-set on Diabetes12 MB
2013CME Questions


Lars Rydén (Chairperson)(Sweden), Peter Grant (Chaiperson)(UK), Stefan D. Anker (Germany), Christian Berne (Sweden), Francesco Consentino (Italy), Nicolas Danchin (France), Christi Deaton (UK), Javier Escaned (Spain), Hans-Peter Hammes (Germany), Heikki Huikuri (Finland), Michel Marre (France), Nikolaus Marx (Germany), Linda Mellbin (Sweden), Jan Ostergren (Sweden), Carlo Patrono (Italy), Petar Seferovic (Serbia), Miguel Sousa Uva (Portugal), Marja-Riita Taskinen (Finland), Michal Tendera (Poland), Jaakko Tuomilehto (Finland), Paul Valensi (France), Jose Luis Zamorano (Spain)

Declarations of Interest of the experts involved in the elaboration of the document.

Endorsed by:

Table of contents: Full Text (ESC Clinical Practice Guidelines)

  • Preamble
  • Introduction
  • Abnormalities of glucose metabolism and CVD
    • Definition, classification and diagnosis, Epidemiology,screening for disorders of glucose metabolism, disorders of glucose mtabolism and CVD, delaying conversion to type 2 diabetes mellitus, recommendations for diagnosis of disorders of glucose metabolism
  • Molecular basis of cardiovascular disease in diabetes mellitus
    • The CV continuum in DM, pathophysiology of insulin resistance in T2DM, endothelial dysfunction - oxidative stress and vascular inflammation, macrophage dysfunction, atherogenic dyslipidaemia, coagulation and platelet function, diabetic cardiomyopathy, the metabolic syndrome, endothelial progenitor cells & vascular repair, conclusions
  • Cardiovascular risk assessment in patients with dysglycaemia
    • risk scores developed for people with DM, evaluation of CV risk in people with pre-diabetes, risk engines developed for people in diabetes, risk assessment based on biomakers and imaging, gaps in knowledge, recommendations for CV risk assessement in diabetes
  • Prevention of CVD in patients with diabetes
    • Lifetsyle, glucose control, blood pressure, dyslipidaemia, platelet function, multifactorials approaches
  • Management of stable & unstable coroary artery disease in patients with diabetes
    • Optimal medical treatment for patients with chronic coronary artery disease and diabetes, revascularization
  • Heart failure and diabetes
    • Prevalence and incidence of HF in T2DM and T2DM in HF, DM and HF morbidity and mortality, pharmacologycal management of HF in T2DM, non-pharmacoloical therapies for HF in DM, glucose lowering treatment in patients with HF, gaps in knowledge, recommendations for management of HF in diabetes
  • Arrhythmias: atrial fibrillation and sudden cardiac death
    • Diabetes mellitus and atrial fibrillation, sudden cardiac death, gaps in knowledge, recommendations for the management of arrhythmias in patients with DM
  • Peripheral- and cerebrovascular disease
    • peripheral artery disease, lower extremity artery disease, carotid artery disease, gaps in knowledge, recommendations for the management of peripheral artery disease in diabetes
  • Microvascular disease in the eyes and kidneys
    • Pathophysiology of microvascular disease, treatment and treatment targets, gaps in knowledge, recommendations for management of microvascular disease in diabetes
  • Patient-centred care
    • General aspects, gaps in knowledge, recommendations for patient-centred care in diabetes

Previous versions

Date TypeJournalissue
2007 Full TextEuropean Heart Journal Supplements (2007) 9 (Supplement C), C3–C74
2007 Executive SummaryEuropean Heart Journal 2007;28:88-136