ESC Working Groups highlights from past ESC Congresses

Review all abstracts and presentations on ESC 365, the Cardiology Knowledge Hub.

ESC Congress 2020 - Digital Experience

Awards

The following ESC Working Groups are pleased to support high-quality research at ESC Congress.

Each Working Group selected the best two abstracts submitted in their topic of expertise.

The first author or presenter of each best abstract is awarded with a financial prize of 500€.

WG on Adult Congenital Heart Disease

• Yiwei Liu (Shanghai, China): Suppression of myocardial HIF-1 by pubertal insulin resistance compromises metabolic adaptation and impairs cardiac function in patients with cyanotic congenital heart disease. e-poster presentation available on demand from Friday 28 August 2020.
• Giulia Costola (London, United Kingdom of Great Britain & Northern Ireland): Early extubation following cardiac surgery in adult congenital heart disease improves post-operative haemodynamics and reduces costs. e-poster presentation available on demand from Friday 28 August 2020.

WG on Aorta & Peripheral Vascular Diseases

• Andrea Guala (Barcelona, Spain): The length of the fusion between leaflets in bicuspid aortic valve is independently related to ascending aorta dilation and flow dynamics alterations assessed by 4D-flow CMR. Best e-poster presentation available on demand from Sunday 30 August 2020.
• Kevin Kris Warnakula Olesen (Aarhus N, Denmark): Microvascular disease, peripheral artery disease, and the risk of lower limb amputation. Advances in Science presentation available on demand from Sunday 30 August 2020.

WG on Atherosclerosis & Vascular Biology

• Elisa Avolio (Bristol, United Kingdom of Great Britain & Northern Ireland): Human adventitial pericytes secrete bioactive factors exerting distinct biological effects on cardiac cells: hints for cardiac repair. ePoster presentation available on demand from Friday 28 August 2020.
• Sebastian Koenig (Freiburg, Germany): Deficiency of the purinergic receptor P2X4 limits atherosclerosis in mice. ePoster presentation available on demand from Friday 28 August 2020.

WG on Cardiovascular Regenerative & Reperative Medicine

• Oisin King (London, United Kingdom of Great Britain & Northern Ireland): Influence of perfusable microvasculature on excitation-contraction coupling in IPSC-derived myocardium. Advances in Science presentation available on demand from Sunday 30 August 2020.
• Yeshai Schary (Tel Aviv, Israel): CRISPR-Cas9-based gene editing of human mesenchymal stromal cells to improve the outcome of cell therapy. ePoster presentation available on demand from Friday 28 August 2020.

WG on e-Cardiology

• Marinka Oudkerk Pool (Amsterdam, Netherlands (The)): Distinguishing sinus rhythm from atrial fibrillation on single-lead ECGs using a deep neural network. Advances in Science presentation, Saturday 29 August 2020, 10:50.
• Tina Stegmann (Leipzig, Germany): Detection of new-onset atrial fibrillation in heart failure patients using daily non-invasive ECG monitoring in the TIM-HF2 telemedicine trial. Advances in Science presentation, Tuesday 01 September 2020, 11:33.

WG on Myocardial Function

• Samuele Ambrosini (Schlieren, Switzerland): Methylation of the hippo signalling effector YAP by SETD7 drives myocardial ischemic injury. Award Session presentation, Sunday 30 August 2020, 10:50.
• Theresa Dolejsi (Innsbruck, Austria): Adult T-cells impair neonatal cardiac regeneration. Blockbusters presentation, Monday 31 August 2020, 08:50.

WG on Pulmonary Circulation & Right Ventricular Function

• Chayakrit Krittanawong (Houston, United States of America): A genome-wide association study identifies novel genetic loci associated with pulmonary embolism. Award Session presentation, Saturday 29 August 2020, 10:10
• Risa Ramadhiani (Kobe, Japan): Endothelial cell premature senescence exacerbates pulmonary arterial hypertension through contact-mediated interaction with vascular smooth muscle cells. Rapid Fire abstract presentation available on demand from Tuesday 01 September 2020

Recommended sessions

WG on Adult Congenital Heart Disease

• Saturday 29 August 2020, 11:45-12:30: Imaging in Congenital Heart Disease
• Sunday 30 August 2020, 10:15-11:00: Tell me how to counsel my patient with adult congenital heart disease
• Available from Sunday 30 August 2020, on demand: Machine learning algorithms to predict prognosis of adult congenital heart disease
• Tuesday 01 September 2020, 15:30-16:30: 2020 ESC Guidelines on Adult Congenital Heart Disease – Live
• Available from Tuesday 1 September 2020, on demand: Systemic right ventricle – Focus with the Experts

WG on Aorta & Peripheral Vascular Diseases

• Saturday 29 August 2020, 11:00-11:45: Aorta and Peripheral Vascular Diseases - Essential Update
• Sunday 30 August 2020, 09:00-09:10: Late-Breaking Science in Peripheral Vascular and Cerebrovascular Disease: VOYAGER PAD and concomitant coronary artery disease
• Monday 31 August 2020, 10:20-10:50: Pharmacotherapy and Intervention for Vascular Disease
• Monday 31 August 2020, 12:45-13:45: Evolving anticoagulation management in venous thromboembolism
• Tuesday 01 September 2020, 10:05-10:15: Imaging the Aorta: State-of-the-art lecture in multi-modality imaging of the aorta

WG on Atherosclerosis & Vascular Biology

• Saturday 29 August 2020, 10:03-10:15: Translating Basic Science Discoveries into Clinical Practice: Activation of invariant natural killer T cells for heart failure therapy
• Sunday 30 August 2020, 10:30-11:10: Young Investigator Award Session Basic Science
• Monday 31 August 2020, 10:30-10:45: Best of Cardiovascular Research: Myeloid cells in atherosclerosis – one cell at the time
• Tuesday 1 September 2020, 09:06-09:18: Epigenetic Drugs: Targeting the ‘Heart’ of Cardiovascular Remodeling: Epigenetic Regulation of Inflammatory gene expression in vascular smooth muscle cells
• Tuesday 01 September 2020, 11:45-12:20: Targeting Metabolism to Mend the Heart

WG on Cardiac Cellular Electrophysiology

• Saturday 29 August 2020, 08:30-09:30: Technological Breakthroughs in Cardiovascular Research: Stepping Stones to Progress in Cardiology
• Saturday 29 August 2020, 09:30-10:15: Translating Basic Science Discoveries into Clinical Practice
• Saturday 29 August 2020, 11:00-11:30: Deep Dive in Basic Science
• Sunday 30 August 2020, 08:30-09:30: Nanotechnology in Cardiovascular Therapy
• Tuesday 1 September 2020, 11:00-11:45: Novel Insights into Atrial Fibrillation: Mechanisms and Therapies

WG on Cardiovascular Pharmacotherapy

• Saturday 29 August 2020, 11:06-11:26: Latest Findings in Cardiovascular Pharmacotherapy
• Saturday 29 August 2020, 11:26-11:56: Challenges in Pharmacotherapy: Heart Failure with mid-Range Ejection Fraction
• Saturday 29 August 2020, 14:30-15:00: Hot Line EMPEROR-Reduced
• Monday 31 August 2020, 10:20-10:54: Controversies in Antithrombotic Therapy: Is Triple Therapy Still Needed in Patients with Atrial Fibrillation Undergoing PCI?
• Tuesday 01 September 2020, 08:30-08:40: Late-Breaking Science in Cardiovascular Pharmacotherapy: THEMIS-PAD Ticagrelor in Patients with and without Peripheral Artery Disease

WG on Cardiovascular Regenerative & Reperative Medicine

• Saturday 29 August 2020, 08:54-09:06: Technological Breakthroughs in Cardiovascular Research: Stepping Stones to Progress in Cardiology: 3D bioprinting: engineering of the human heart
• Saturday 29 August 2020, 11:31-11:41: Cornerstones in the Management of Advanced Heart Failure: Patient referral and prognosis in advanced heart failure
• Saturday 29 August 2020, 11:53-12:05: The Scientists of Tomorrow Meet the Scientists of Today: Cardiovascular regeneration: the past and the future
• Monday 31 August 2020, 09:11-09:22: The Future of Personalised Medicine in Cardiomyopathy: Targeted therapies in hypertrophic cardiomyopathy
• Monday 31 August 2020, 11:25-11:35: Novel Pathways that Regulate Ventricular Function: Cardiomyocyte dedifferentiation and regeneration after injury and inflammatory cytokines in heart failure

WG on Cardiovascular Surgery

• Sunday 30 August 2020, 09:34-10:14: How Should I Treat Primary Mitral Regurgitation with Poor Left Ventricular Function?
• Monday 31 August 2020, 11:34-12:04: Planning Aortic Stenosis Treatment for Life: Implications of Valve Durability
• Monday 31 August 2020, 11:38-12:13: When To Intervene in Valvular Heart Disease: Guidelines and New Evidence
• Tuesday 01 September 2020, 08:30-09:10: Meet the Experts - Left Ventricular Mechanical Support Devices: When, How and in Whom
• Tuesday 01 September 2020, 11:57-12:32: Expert Advice - Acute and Long-Term Management of Thoracic Aortic Dissection

WG on Cellular Biology of the Heart

• Available from Friday 28 August 2020, on demand: Ponatinib induces vascular toxicity through the Notch-1 signaling pathway
• Available from Saturday 29 August 2020, on demand: Aging-associated cardiac dysfunction and leaky gut in heterozygous Akap1 knockout mice
• Sunday 30 August 2020, 11:10-12:00: Molecular mechanisms that modulate ischemia injury: Online Session

WG on Coronary Pathophysiology & Microcirculation

• Available from Saturday 29 August 2020, on demand: State-of-the-art lecture - How to investigate suspected coronary artery disease in 2020
• Available from Sunday 30 August 2020, on demand: Microcirculation controlling cardiac function
• Sunday 30 August 2020, 09:18-09:53: Guidelines in Practice - Managing Patients with Angina and without Obstructive Coronary Artery Disease
• Sunday 30 August 2020, 09:53-10:28: Young Investigator Award Session Coronary Pathophysiology and Microcirculation
• Monday 31 August 2020, 09:45-10:45: Best of Cardiovascular Research
• Tuesday 01 September 2020, 11:06-11:46: Advances in Invasive Coronary Physiology

WG on Development, Anatomy & Pathology

• Saturday 29 August 2020, 11:53-12:05: The Scientists of Tomorrow Meet the Scientists of Today: Cardiovascular regeneration: the past and the future
• Saturday 29 August 2020, 12:18-12:30: Imaging in Congenital Heart Disease: Beyond 3D printing: applying virtual reality in congenital heart disease imaging
• Monday 31 August 2020, 08:50-09:00: Blockbusters from the Young in Basic Science: Adult T-cells impair neonatal cardiac regeneration
• Monday 31 August, 09:40-09:50: Meet the Experts - Comprehensive Risk Prediction in Cardiomyopathy: Imaging, Pathology, Genetics: Comprehensive risk prediction in the dilated heart
• Monday 31 August 2020, 11:00-11:11: Sudden Death in Relation to Sport and the Impact of Toxicology: The burden of sudden death in athletes with normal heart

WG on e-Cardiology

• Saturday 29 August 2020, 10:40-11:20: Machine Learning Approaches to ECG Interpretation: State of the Art
• Saturday 29 August 2020, 11:40-12:20: Digital Health for General Cardiologists - Threat or Opportunity?
• Monday 31 August 2020, 09:50-10:30: Digital Health: a 2020 Snapshot
• Monday 31 August 2020, 10:50-11:10: The Digital Twin: a Mirror for Personalized Medicine
• Tuesday 01 September 2020, 09:10-09:40: New Frontiers in Artificial Intelligence

WG on Myocardial & Pericardial Diseases

• Saturday 29 August 2020, 09:30-10:10: Meet the Experts - Challenging Cases in Cardiogenic Shock, Meet the Experts Focused Case Discussions
• Monday 31 August 2020, 09:00-09:45: The Future of Personalised Medicine in Cardiomyopathy, ESC Council on Cardiovascular Genomics
• Monday 31 August 2020, 09:10-09:50: Meet the Experts - Comprehensive Risk Prediction in Cardiomyopathy: Imaging, Pathology, Genetics
• Monday 31 August 2020, 15:00-15:30: Faces and Cases: Improving the Management of Patients with Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
• Tuesday 01 September 2020, 09:10-09:50: Meet the Experts - Heart Disease Impacts Many Women in Many Ways

WG on Myocardial Function

• Saturday 29 August 2020, 09:30-10:15: Translating Basic Science Discoveries into Clinical Practice
• Saturday 29 August 2020, 11:00-11:30: Deep Dive in Basic Science
• Saturday 29 August 2020, 11:30-12:05: The Scientists of Tomorrow Meet the Scientists of Today
• Sunday 30 August 2020, 10:30-11:10: Young Investigator Award Session Basic Science
• Monday 31 August 2020, 11:35-12:20: Mechanisms of Chemotherapy-Induced Cardiotoxicity

WG on Pulmonary Circulation & Right Ventricular Function

• Saturday 29 August 2020, 08:30-08:40: Deep Dive into Pulmonary Arterial Hypertension and Myocardial Disease: Long-term outcomes in newly diagnosed pulmonary arterial hypertension (PAH) patients receiving initial triple oral combination therapy: Insights from the randomised controlled TRITON study
• Monday 31 August 2020, 09:00-09:35: Guidelines in Practice - 2019 Guidelines on the Diagnosis and Management of Acute Pulmonary Embolism: Guidelines in Practice - Acute pulmonary embolism or chronic thromboembolic pulmonary hypertension?
• Monday 31 August 2020, 11:16-11:27: Pulmonary Hypertension in Left Heart Disease: How do we treat pulmonary hypertension in advanced heart failure?
• Monday 31 August 2020, 14:30-15:00: Hot Line HOME-PE: HOME-PE - Hospitalisation or Outpatient Management of PE Patients - HESTIA vs. Simplified PESI
• Tuesday 01 September 2020, 11:24-11:57: Latest Findings in Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure: RELAX-PE study: real-life validation of the age-adjusted D-dimer cutoff to exclude PE

WG on Thrombosis

• Saturday 29 August 2020, 10:10-10:44: Young Investigator Award Session Thrombosis
• Monday 31 August 2020, 09:30-09:40: Atherothrombosis: New Therapeutic Targets: Targeting new coagulation factors in atherothrombosis
• Monday 31 August 2020, 09:00-09:33: Controversies in Antiplatelet Treatment: Is Short-Term Dual Antiplatelet Therapy Safe and Effective after PCI?
• Monday 31 August 2020, 11:48-12:28: Dual versus Triple Antithrombotic Therapy for Patients with Atrial Fibrillation Undergoing Stenting

ESC Congress 2019, Paris

WG on Adult Congenital Heart Disease

• Differences in the management and outcomes in congenital versus acquired heart disease (Sat 31 Aug. 09:00-10:30)
• Give me the evidence in adult congenital heart disease (Mon 2 Sept. 11:00-12:30)
• Undiagnosed cardiac defects in the adult (Mon 2 Sept. 14:30-15:40)
• Meet the experts. Challenges in the adult congenital heart disease care (Tue 3 Sept. 8:30-10:00)
• Transposition of the great arteries: what have we learnt? (Tue 3 Sept. 16:40-17:50)

WG on Aorta & Peripheral Vascular Diseases

• 2019 ESC Guidelines on Acute Pulmonary Embolism
• 2019 ESC Guidelines on Chronic Coronary Syndromes
• Aorta and peripheral vascular disease: Essential Update

WG on Atherosclerosis & Vascular Biology

• Application of single‑cell genomics in cardiovascular research
• Tackling the inflammatory side of atherosclerosis
• Beyond lipid lowering: can atherosclerosis be reversed?
• Late Breaking Basic and Translational Science Atherosclerosis and Aortic Stenosis
• Novel insights in atherosclerosis

WG on Cardiovascular Regenerative & Reperative Medicine

Session: Cardiac tissue engineering: disease modelling and novel therapeutics

Presentation: The challenge of mature cardiac tissue formed from pluripotent stem cell-derived cardiomyocytes

Session: Mechanisms behind intrinsic myocardial repair and regeneration

Presentation: Extracellular matrix in cardiac repair and regeneration

Presentation: Myocardial repair and regeneration: state of the art

Presentation: T-cells in cardiac repair and regeneration

Session: Cells, Cell Cycle, Cell Senescence, Cell Death

Presentation: CRISPR/dCas9 Activated Expression of Cardiomyocyte Differentiation Factors in CDCs in Myocardial Infarctions

Presentation: N-cadherin promotes cardiac regeneration by stabilizing beta-catenin

Session: IPS disease modelling and congenital heart disease

Presentation: Differentiation of iPS-derived cardiac mesoderm cells into cardiomyocytes using inducible shRNA

Session: Insights into cardiac cell biology for repair and regeneration

Presentation: Exosomes mediate myocardial regeneration of cardiac progenitor cells in a swine model of dilated

Presentation: The cardiac endothelial cell transcriptome in neonatal, adult, and remodeling hearts

WG on Cellular Biology of the Heart

• Cardiac tissue engineering: disease modelling and novel therapeutics
• Inspirational Lecture in Translational Science
• Cardio-Oncology: Novel mechanisms and clinical implications

WG on Coronary Pathophysiology & Microcirculation

• Myocardial infarction and non-obstructive coronary arteries (MINOCA): what a headache!
• MINOCA - Unravelling the enigma
• The cardiovascular dangers of age and sex
• 2019 ESC Guidelines on Chronic Coronary Syndromes

WG on Development, Anatomy & Pathology

• Application of single-cell genomics in cardiovascular research (Basic Science Symposium, Scientists of Tomorrow)
• Insights into cardiac cell biology for repair and regeneration (Moderated Poster Session)
• Mechanisms behind intrinsic myocardial repair and regeneration (Basic Science Symposium)

WG on e-Cardiology

• Digital health solutions in clinical practice: do not be afraid! Charles Alesi
• Future impact on digital health on patients - guardian angel or Big brother? Martin R Cowie
• Personal Digital Health Technology - a new era in CVD prevention. Carl J Lavie
• Telemedicine-assisted monitoring heart failure using ICDs/CRTs. Gerhard Hindricks
• Wearable trackers - potential and pitfalls of digital health devices. Nicola Stariton
• Wearable trackers - stimulus for fitness or just another gadget? Emilio Vanolli

WG on Pulmonary Circulation & Right Ventricular Function

•  2019 ESC Guidelines on Acute Pulmonary Embolism
• Controversies in the management of pulmonary hypertension and venous thromboembolism
• Meet the Task Force of the 2019 ESC Guidelines on Acute Pulmonary Embolism: Going with the Guidelines in difficult clinical situations
• Advances and unmet needs in chronic thromboembolic pulmonary hypertension around the globe
• Contemporary management of pulmonary hypertension
• How to diagnose and treat pulmonary embolism
• Mitochondrial metabolism in pulmonary arterial hypertension and right ventricular function
• New treatments for pulmonary vascular disease
• Meet the Experts - Cardiovascular disease in pregnancy - Panel. Case 1: pulmonary hypertension and pregnancy
• How should I treat acute pulmonary embolism?
• Sudden cardiac death due to left main compression syndrome in pulmonary arterial hypertension
• Pulmonary circulation clinical cases
• Pulmonary arterial hypertension - The importance of assessing risk in treatment and management to delay disease progression
• Initial combination therapy in pulmonary arterial hypertension: now the standard of care?
• Setting up a pulmonary embolism response team: how I built my pulmonary embolism management network