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Berlin Cardiovascular Development Meeting 2013

Add to calendar26/09/20130:00 29/09/20130:00 Europe/Paris Berlin Cardiovascular Development Meeting 2013 true DD/MM/YYYY

You missed the event? Read the report of the Chairman

 Scientific ProgrammeThis year, the meeting was held in the Max Delbrück Center for Molecular Medicine of Berlin.

 Submit your abstractTake part in the Programme! Get involve! Closed

 Registration & HotelRegister for the meeting with early fee or reduced fee.

 Sponsor and Exhibition The Working Group wishes to express its thanks to the sponsors, who contributes to the success of the meeting 

 Travel & CityLearn more about Berlin an how to access the city



Scientific Programme:

Thursday 26 September

11:00 –11:30  Registration 
11:30 – 13:00  Hands-on Workshop - Session 1 
11:30 – 12:00  David Sedmera : Normal – Conduction, valves, myocardial architecture*
12:00 - 12:30 Katharina Wassilew : Cardiomyopathies vs normal ventricles* 
12:30 - 13:00  Yen Ho: Congenital heart defects in animals*
13:00 – 13:45 Lunch buffet 
13:45 – 17:30  Hands-on Workshop - Session 2 
13:45 – 14:00 Robert Kelly: Development of conotruncal malformations
14:00 - 14:20 Lucile Houyel: Clinical perspective of Conotruncal malformations
14:20 - 15:00 Lucile Houyel: Conotruncal malformations (paeds/fetal)*
15:00 -  15:40  Mary Sheppard: Adult congenital hearts*
15:40 -  16:00 Tea/coffee
16:00 -  17:30 Hands-on  (ALL)

 Pre Congress Dinner - 12 Apostel 

* live video demonstrations (requires video camera and audiovisual technician) 
The bus will drive attendees directly to the dinner place.
Acceptance only upon registration - limited places

Friday 27 September 2013

09:00 – 10:00 Registration 
10.00 – 12:30 Scientific Program - Session 1 - Translational research
10:00 - 10:30 ESC: Michael Bader: Peptide hormones in cardiac development and pathophysiology
10:30 - 10:45 Katharina Wassilew
Morphological spectrum of autoimmune myocarditis in a rat model
10:45 - 11:00 Jean-Marc Schleich
A method for accurate, non-destructive diagnosis of congenital heart
defects from heart specimens
11:00 - 11:15 Meiem Mostefa Kara
Anatomy of the ventricular septal defect in congenital heart defects:
random or systemic association?
11:15 - 11:30

 Ross Breckenridge
Ambient oxygen levels act as a maturational signal in the neonatal

11:30 - 11:50  Oleksandra Koval
Toxic substances in heart tissues of children with cardiovascular
12:00 - 13:00 Lunch buffet 
13:00 - 15:30  Scientific Program - Session 2 - Cardiovascular developmental biology
13:00 - 13:30 ESC:  Rolf Bodmer:
13:30 - 13:45  Jose-Luis de la Pompa: Sequential Notch activation during cardiac chamber development and disease
13:45 - 14:00  Veronica Lombardo: Endocardial chamber differentiation
14:00 - 14:15 Melanie Philipp: GRK5 governs heart development through regulation of symmetry breaking
14:15 - 14:30  Werner Mohl: Can cardiac developmental stimuli regenerate myocardium via Mechanotransduction of hemodynamic energy in coronary veins?
14:30 - 14:45  Jorg-Detlef Drenckham: Impaired heart development alters postnatal cardiac growth control and stress response
14:45 - 16:15 Tea/Coffee/Beer Poster Session
16:15 - 18:15  Scientific Program - Session 3 - Cardiovascular developmental biology
16:30 - 17:00 ESC:  Thomas Braun
17:00 - 17:15  Andy Wessel: Molecular Mechanisms Regulating the Development of the Dorsal Mesenchymal Protrusion
17:15 - 17:30  Brigitte Laforest: Requirement of HOXB1 for cardiac outflow tract development*
17:30 - 17:45  Karen Koefoed: The E3 ubiquitin ligase SMURF1 is involved in heart development and cardiomyogenesis
17:45 - 18:00  Claudia Matthäus: Functional characterization of the cell adhesion molecule CAR (coxsackie- and adenovirus receptor) in the developing heart and nervous system
18:00 - 18:20  AEPC -  Beatrijs Bartelds: Right ventricular adaptation in Congenital Heart Diseases
 Galadinner Meistersaal, Potsdamer Platz  


Saturday 28 September 2013

09:00 - 10:30 Scientific Program - Session 4 - Cardiovascular systems across the evolutionary spectrum
09:00 - 09:30 ESC: Didier Stainier: Cardiovascular development in zebrafish
09:30 - 09:45  Bjarke JensenEvolution of the building plan of the heart
09:45 - 10:00  Robert PoelmanEvolution and development of ventricular septation: role of the epicardium.
10:15 - 10:30  Daniela Panakova: Wnt11 non-canonical signaling patterns cardiac form and function
10:30 - 10:45  Robert Opitz: A Zebrafish Model of Netrin1 Deficiency Reveals Defective Vascular Development Concurrent With Abnormal Endodermal Organ Morphogenesis
10:45 - 11:00  Tea/coffee 
11.00 – 12:45 Scientific Program - Session 5 - Cardiac growth, progenitors & regneration
11:00 - 11:30ESC: Jun K. Takeuchi
11:30 - 11:45 Fabienne Lescroart  : Two temporally distinct populations of Mesp1 progenitors contribute to the mouse heart development
11:45 - 12:00 Yuika Morita : A novel defined factor directly specifies cardiac lineages from pluripotent
stem cells and promotes heart regeneration
12:00 - 12:15  Amelia Aranega : miR-27b, miR-23b and miR-200 modulate cardiomyocite differentiation
from mouse embryonic stem cells
12:15 - 12:30 

 Ina Strate: The Glypican 4 Knypek is required for cardiomyocyte differentiation of second heart field progenitor cells by attenuating Wnt/β-catenin signaling.

12:30 - 12:45 Jan-Willem Buikema: Wnt/β-catenin Signaling Directs the Regional Expansion of early First and Second Heart Field-derived Ventricular Cardiomyocytes
12:45 – 13:30  Lunch buffet
13:30 – 15:30  Scientific Program - Session 6 - Cardiovascular Genetics
13:30 - 14:00 ESC: David Brook: Studies of Genes involved in Congenital Heart Disease
14:00 - 14:15  Lars-Allan Larsen: Genome wide identification of human cardiac developmental genes located within regions associated with congenital heart disease
14:15 - 14:30  Cornelia Dorn: A multi-level approach comprising gene mutation analysis and expression profiling shows complex genetics of isolated Tetralogy of Fallot
14:30 - 14:45 Thomas Brand: Popdc genes and cardiac pacemaking: The molecular basis of genetic redundancy
14:45 - 15:00 Cinzia Caprio: p53 mutation partially rescues the Tbx1 mutant phenotype
15:00 - 15:20 DGPK: Sabine Klaassen: Mutation of the transcription factor PRDM16 causes cardiomyopathy
15:20 - 16:30 Tea/Coffee/Beer Poster Session
16:30 - 18:20 Scientific Program - Session 7 - Cardiovascular Genetics and epigenetics
16:30 - 17:00 ESC: Antonio Baldini: Chromatin interactions and phenotypic rescue in a mouse model of DiGeorge Syndrome
17:00 - 17:15  Ian Dykes: Zic2 is required for left-right patterning and mutation results in right atrial isomerism
17:15 - 17:30 Cui Huanhuan: Muscle specific genes are characterised by specific histone marks
17:30 - 17:50  AEPC - Ingegerd Östman-Smith: Hypertrophic cardiomyopathy- is genotype or phenotype more important in determining risk of sudden death?
17:50 - 18:00  Closing remarks 
18:00 - 18:20 ESC WG DAP General Assembly 

Faculty Dinner - Restaurant Käfer/Reichstag  


Posters guidelines:

The poster will have to be displayed from 27 September, 10:00 (your arrival) to 28 September 18:00 (your departure).

Poster size:  A0 poster size: 1,00m (width) x 1,20m (high) or 84,1cm (width) x 118,9cm (high) portrait.

Certificate of attendance:

Given at the registration desk, on 28 September, upon request.

Submit your abstract:

Abstract submission is now closed

The Organising Committee Chairperson invite you to submit your research and actively participate in the scientific programme
Submission deadline: Extended to 30 July 2013

Each abstract should have the following information:

1 -Topic: Which key word fits best with the abstract below:

  • Cardiovascular developmental biology
  • Cardiovascular pathology
  • Cardiac growth, progenitors & regneration
  • Cardiovascular systems across the evolutionary spectrum
  • Cardiovascular Genetics
  • Translational research

2 -Oral presentation: Please indicate if it will be an oral presentation or not.

3 -Short title: Mandatory

4 -Author list: First and last name of all authors

5 -Email address of presenter

6 -Body of the abstract: no more than 250 words


Registration & Hotel

Hotel: Registration for the hote are closed - as the deadline was 15 July

Room rates have been negociated with the Motel One Berlin - Mitte.

May you need to book an hotel room, please contact the hotel by yourself from now. A shuttle will be arranged from the Motel One-Mitte to the meeitng venue.

Note that the rooms can be used as single or double and that there is the option to share a room if just one person books it for two.


Check your category in the table below and register for the meeting.
Note that you can also register for the hands-on course and the pre-congress dinner (26 September).

Standard Early Fee - until the 30 June No more available€460
Standard Early Fee with hotel booking - until the 30 June - No more available€782
Standard Late Fee - until 20 September €520
Standard Late Fee with hotel booking - until the 15 July - No more available €842
 PhD students / postdocs / trainees €280
 PhD students / postdocs / trainees with hotel booking - until the 15 July - No more available €602
 ESC WG Member Fee* - until 20 September €350*
 ESC WG Member Fee* with hotel booking - until the 15 July- No more available €672*


Hands-On Course - until 20 September  €130
Pre-Congress Dinner - until 20 September  €55

The price includes lunch, coffee/tea breaks, bus transfer from hotel to venue (morning/evening) and Gala Dinner on Friday 27th September 2013 at the Meistersaal  (Potsdamer Platz)

* This special rate is allocated to working group members who submits an abstract.
How to become a member: join the Working Group membership in few clicks and benefit from reduced fee. Membership is free of charge!

Meeting venue: Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch – Conference Center, MDC.C, Robert-Rössle Str 10 - 13125 Berlin

About the MDC:
The venue will take place at the MDC.C, the conference center of the Max Delbrück Center (MDC) for Molecular Medicine. The MDC is a major biomedical research institute located in the northeastern corner of Berlin, Germany. It was founded in 1992 with a mission of translating discoveries from molecular research into applications to improve the prevention, diagnosis, and treatment of major human diseases. The site in Berlin-Buch, home to hospital clinics, research institutes and a flourishing biotech industry, is fertile ground for interdisciplinary and patient-oriented research. As a testament to its success, the MDC has been ranked 14th in the Thompson Reuters list of the world’s 20 best research institutes for molecular biology and genetics, based on our publication record.

Thanks to:

The Charité:
The Charité is one of the largest university hospitals in Europe. Here, 3800 doctors and scientists heal, do research and teach at the top international level.  More than half of the German Nobel Prize winners in medicine and physiology come from the Charité, among them Emil von Behring, Robert Koch and Paul Ehrlich. The Charité also has an international reputation for excellence in training. It extends over four campuses with more than 100 clinics and institutes bundled under 17 CharitéCenters. 

 Social event:

The traditional Gala Dinner wil be held on Friday 27th September 2013 at the Meistersaal  (Potsdamer Platz)

About the Meistersaal:
Situated right next to Potsdamer Platz, the Meistersaal is a beating heart of cosmopolitan Berlin. Far from being just a venue for major exponents of contemporary popular and art music, it was also used to showcase such well-renowned artists as John Heartfield and George Grosz and earned a reputation for literary readings by such authors as Kurt Tucholsky, whose famous Malik publishing house was located in the building.


The ESC Working Group on Development, Anatomy and Pathology wishes to thank the support of their sponsors:

  • The Company of Biologists
  • Data Sciences International

 Data Science International

Travel & City:

Travel & City:

About Berlin: Berlin the capital of Germany is dynamic, cosmopolitan and creative, allowing for every kind of lifestyle.

East meets West in the metropolis at the heart of a changing Europe. Germany's largest city is a city of opportunities just waiting to be seized in all areas, like entertainment, recreation, economy, science and academic life.

Berlin has a long tradition as a city of medicine and medical technology. The Berlin Charité Hospital is the largest University Hospital in Europe.

The metropolis is home to world-renowed universities, research institutes, sporting events, orchestras, museums and personalities. Berlin's urban landscape and historical legacy has made it a popular setting for international film productions.

Recognised for its festivals, contemporary architecture, nightlife and avant-garde arts, Berlin has evolved into a focal point for individuals attracted by liberal lifestyle, modern zeitgeist and low cost of living.

Berlin is the third most visited tourist destination in Europe.

Banks are usually open from 08:30 to 16:00 during the week and many stay open until 18:00 on Thursday. At airports and main train stations, banks have longer hours, opening from around 06:30 to 22.30.  Most banks have English-speaking staff and they all can handle International transactions. Commissions may be charged on a foreign transactions and passports will be required as proof of identity. The city is well supplied with cash dispensers, which take most major credit cards.

Berlin has a temperate climate. Summers are warm with average high temperatures of 22–25°C (mid 70s F) and lows of 12–14°C (mid 50s F). Spring and autumn are generally chilly to mild. Berlin's built-up area creates a microclimate, with heat stored by the city's buildings. Temperatures can be 4°C (7°F) higher in the city than in the surrounding areas.

The monetary unit in Germany is Euro (€) / EUR.

In Germany, electricity is supplied at 220V
50 Hz and power sockets are of 2 or 3 pin round type.

Time Zone
Berlin is located in the GMT+1 time zone.

Useful links
Berlin Tourism - Official Web Site
City of Berlin - Official Web Site

Travel to and around the city

By Air

You can fly to Berlin from many international airports. Tegel and Schönefeld are the largest of Berlin's three airports, where a lot of flight connections are offered. Schönefeld lies just outside Berlin's South-eastern border while the other two airports lie within the city.

Airport and Flight Information:
Tel.: +49 180 5000 186 / Web Site

By Car

All motorways to Berlin lead to the Berliner Ring (A10). From there you can get to the inner city on various access roads. If your destination is situated in the western city, you should use the A115. The A113 takes you to the south-east quarters. For access to the north of the city, make use of the A114 for Pankow/Weissensee, for Reinickendorf the A111.

Berlin has two city centres: city west and city east. Please notice, that the direction sign "Mitte" leads to the district "Mitte", that means city east. The western city is situdated around the Kurfürstendamm, driving time from "Mitte" appr. 15 minutes.

By Train

You can reach Berlin from all directions by using the fast InterCityExpress, InterCity, EuroCity and InterRegio Trains.

All train stations are well connected to the public transport system.
Berlin's new central station "Hauptbahnhof" is located in the city centre. It is an impressive example of contemporary architecture opened on May 28, 2006. A new railway concept with new stations was also installed.