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Post Doctoral Fellowship

Post-Doc in cardiovascular metabolism at the University of Zurich



Postdoc in cardiovascular metabolism

A postdoctoral position in the field of cardiovascular metabolism is available in the group of cardio-metabolic research at the Institute of Clinical Chemistry of the University and University Hospital Zurich.

Your profile:

We are looking for a highly motivated candidate with a PhD, MD or MD/PhD degree with a strong background in cardiovascular (endothelial or vascular biology) and/or metabolic disease. Qualified applicants should have a strong record of achievements as evidenced by first-author research papers published in peer-reviewed journals and have a strong interest in a multidisciplinary approach to experimental and clinical research. The ideal candidate shows initiative, a vigorous “Can Do“-mentality and ambition to succeed. The candidate is reliable and well organized, and shows social skills to work in an international team; hands-on experience with cardiovascular/metabolic animal models are required (e.g., metabolic phenotyping of rodent model of obesity, diabetes, genetically modified strains; surgical skills are a plus). (Cardiovascular) laboratory techniques will include flow cytometry, endothelial cell isolation, single cell RNA sequencing, myograph vascular studies, advanced imaging techniques, i.e. echocardiography. Prior experience on primary endothelial and adipocytes research are of advantage. The ability to design, evaluate and report research is required as well as excellent verbal and written communication skills in English.

The project:

The project combines basic and clinical research. We work in close collaboration with the laboratory of Translational Nutrition Biology at ETH Zurich and the Veterinary Physiology at the University of Zurich.

The dysfunction of endothelial cells is a key player in cardiovascular and metabolic disease. However, the molecular mechanisms that disrupt endothelial homeostasis remain unclear. We examine the crosstalk between gut hormones, adipose tissue, and the cardiovascular system in health and disease. Samples collected from animal model or patients with obesity, type 2 diabetes and after bariatric surgery or other types of weight loss treatments will be analyzed in parallel.

This position requires a direct involvement in the experimental and clinical arms of the study and close interaction/supervision of Master and PhD students.

Start:

Upon agreement. The Position is available on a full time basis for one year in the first instance, further extension is available based on performance.

Please send your complete application material, including cover letter, CV, statement of motivation, list of publications, and of 2 contacts for reference combined into one single PDF-file to: elena.osto@uzh.ch