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Post-doc position in cardiovascular research

University of Geneva

Post-doc position in cardiovascular research focused on smooth muscle cell diversity in atherosclerosis



Postdoctoral position in atherosclerosis research field
Faculty of Medicine - University of Geneva - Switzerland
Job description
The selected candidate will perform a research project in Prof. Marie-Luce Bochaton-Piallat’s laboratory, situated at the University of Geneva (Department of Pathology and Immunology) and contribute to deciphering the mechanisms involved in the development of atherosclerosis.
Atherosclerosis is known to be the underlying cause of cardiovascular disease, which remains the leading cause of death in developed countries. Prof. Bochaton-Piallat’s laboratory specializes on the role of smooth muscle cells (SMCs) in the initiation and progression of atherosclerosis. For decades, SMCs have been considered as beneficial players in the pathogenesis of atherosclerosis by protecting the plaque from rupture. However, SMCs could exhibit remarkable phenotypic plasticity, acquire deleterious phenotype and participate in atherosclerotic plaque vulnerability. The candidate will have the opportunity to work in dynamic, friendly, creative and collaborative environment.
The candidate will perform in-vitro and in-vivo studies and use various experimental models. Main techniques and skills used in our laboratory include: mouse model of atherosclerosis, including state-of the-art lineage tracing mouse models, mouse microsurgeries, human sample-based studies, primary cell culture, molecular biology, immunohistochemistry, immunofluorescence, Western blot, FACS, ELISA, microscopy (fluorescent, confocal, scanner, live imaging), image analysis.
Recent publications related to the project.
Chaabane et al. BBA. Mol. Cell Res. 2015, 1853:2144-2157. PMID: 25110349
Allahverdian et al. Cardiovasc. Res. 2018. 114:540-550. PMID: 29385543
Sakic et al. Cardiovasc Res. 2020. Online ahead of print. PMID: 33135065
Website. http://www.unige.ch/medecine/pati/en/groupes/646bochatonpiallat/

Profile
The successful applicant will have a PhD in cell biology, biochemistry and/or molecular biology, with particular focus on vascular biology/cardiovascular disease. Experience in the development of mouse lineage-tracing models will be appreciated. The candidate needs to have creative, constructive and self driven mindset, strong work ethics and good organizational skills to contribute with ideas as a team player who likes to collaborate with others. High proficiency in written and spoken English language is a requirement. Experience from other international environments is a plus.
Application
Application file must include motivation letter, CV and publication list, name and address of two referees. Email to marie-luce.piallat@unige.ch.
We are looking forward to your application!