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2023 ESC Guidelines for the management of endocarditis

ESC Clinical Practice Guidelines

The current guidelines have been developed to support healthcare professionals with the diagnosis and management of patients with infective endocarditis, an infrequent but oftentimes fatal disease that can present with multiple different clinical scenarios. The last version of the ESC Infective Endocarditis Guidelines was published in 2015. Since then there have been multiple developments in the care of patients with infective endocarditis including refinements of the indications for antibiotic prophylaxis, improvements in diagnostic capabilities, establishment of endocarditis teams and heart valve centres, identification of patients eligible for outpatient antibiotic therapy, diagnosis and risk-stratification of patients suffering complications of endocarditis (in particular stroke), management of patients with transcatheter heart valve- and cardiac implantable electronic device-associated infective endocarditis, and patient-centred care during the acute and follow-up phases of this challenging disease. In addition, the 2023 version of the Guidelines includes a new diagnostic algorithm, which will be particularly helpful in correctly classifying patients. The current document should serve as a guide for clinicians involved in the diagnosis and management of infective endocarditis patients and should lead to improved outcomes for this serious disease.    

Infective Endocarditis
Myocardial Disease
Congenital Heart Disease and Pediatric Cardiology
Pathophysiology and Mechanisms
Epidemiology, Prognosis, Outcome
Valvular Heart Disease
Pericardial Disease
Diagnostic Methods
Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
Cardiac Implantable Device-related Endocarditis

Main resources

Scientific Presentation at ESC Congress 2023

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More resources

ESC TV Interview

The essentials of the Guidelines in just a few minutes.

Congress News Article

Insights from the Chairs of the Guidelines Task Force.

Slide set

Educational material.

ESC Pocket Guidelines App

Have the ESC Pocket Guidelines with you all the time.

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A lifelong learning series

Expand your knowledge of endocarditis with these ESC resources.

eLearning course

on 2023 ESC Guidelines on Endocarditis.

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