Dr. Hisao Ogawa,
This Clinical Seminar will provide new information on mechanisms, diagnosis and treatment of coronary spasm, a frequently neglected but important mechanism of disease. Indeed, coronary spasm plays a key role in vasospastic angina and an important role in all acute coronary syndromes. Furthermore, not rarely, it is refractory to current therapeutic approaches. Dr. Shimokawa lectured the pathogenetic mechanism of coronary spasm. He explained that inflammation is important in the mechanism, and the importance of Rho-kinase. He explained that coronary spasm is related not only to vasospastic angina, acute coronary syndrome but also coronary artery treated with drug-eluting stents. Dr. Sechtem talked about the diagnostic challenges, especially Acetylcholine testing. He pointed out that the importance of coronary spasm in acute coronary syndrome in Caucasian patients. Dr. Ozaki presented the therapeutic challenges. He presented that coronary spasm is more frequent in Asians than in Caucasians, the therapy of calcium channel blockers, statins is effective, there is the fluctuation of spasm in terms of location in the coronary artery, limitations of percutaneous coronary intervention exist. Dr. Kaski explained the long-term prognosis, and pointed out that acute myocardial infarction and sudden death are observed in 10-20% of the patients with coronary spasm. He further emphasized the problems of the out-of-hospital cardiac death and the indications of implanted cardiac defibrillators. This Seminar is very important in the point that coronary spasm is discussed in the European Cardiac Society (ESC).
Mechanisms and outcome of vasospastic angina
Our mission: To reduce the burden of cardiovascular disease
© 2017 European Society of Cardiology. All rights reserved