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Our mission is to promote excellence in research, practice, education and policy in cardiovascular health, primary and secondary prevention.
Our mission is to reduce the burden of cardiovascular disease through percutaneous cardiovascular interventions.
Improving the quality of life and reducing sudden cardiac death by limiting the impact of heart rhythm disturbances.
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The ESC Working Groups' goal is to stimulate and disseminate scientific knowledge in different fields of cardiology.
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Dr. Thomas Felix Luescher
Nico HJ Pijls,
Presenter | see Discussant report
Nico HJ Pijls, FESC (Netherlands)
List of Authors: Nico H.J. Pijls, Pim A.L. Tonino, Bernard De Bruyne, Volker Klauss, Ganesh Manoharan, Thomas Engstrom, Peter N. Ver Lee, Philip A. MacCarthy, Keith G. Oldroyd, William F. Fearon Abstract: Introduction: In patients with multivessel coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI) it is unclear whether routine measurement of fractional flow reserve (FFR) in addition to angiography improves outcome. Methods: At 20 U.S. and European medical centers, 1005 patients with multivessel CAD were randomized to PCI with drug-eluting stents (DES) guided by angiography alone or guided by FFR measurements. Prior to randomization, lesions requiring PCI were indentified based on their angiographic appearance. Patients randomized to angiography-guided PCI underwent stenting of all indicated lesions, while those randomized to FFR-guided PCI underwent stenting of indicated lesions only if FFR was <= 0.80. The primary endpoint was the rate of death, nonfatal myocardial infarction or repeat revascularisation at 1 year. Results: Baseline characteristics were similar. The 1-year event rate was 18.3% in the angiography-guided group and 13.2% in the FFR-guided group (P=0.02). Conclusion: Further follow-up data, subgroup data, and cost-efficiency data will be shown.
Discussant | see Presenter abstract
Thomas Felix Luescher, FESC (Switzerland)Presentation webcast
Fractional flow reserve versus angiograhpy for guiding pci - 2 year outcome
This congress report accompanies a presentation given at the ESC Congress 2009. Written by the author himself/herself, this report does not necessarily reflect the opinion of the European Society of Cardiology.
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