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The clinical relevance of myocardial necrosis during percutaneous coronary intervention


  • Putting the new definition into perspective. F Weidinger (Vienna, Austria)  
  • What causes biomarkers elevation - insights from intravascular ultrasound and magnetic resonance imaging. A P Banning (Oxford, Great Britain)  
  • Impact on long-term outcome. C Cavallini (Perugia, Italy)  
  • How to prevent? J Fajadet (Toulouse, France)  


As Chairperson, we had four presentations reviewing the new definition of myocardial infarction, the impact on post PCI procedures, as well as the significance of CK and troponin elevation.

It was mentioned that, although CK-MB elevation five times has a significant impact on long-term mortality, times three is the cut-off value to be taken into consideration.

Although troponin elevation may be related to the outcome, the relation is not as clear as for CK.

The presentation by Dr Banning with insights from IVUS and MRI postulated two causes for biomarker elevation: side branch occlusions and embolization with impact on wall motion.

Dr Fajadet mentioned considerations for prevention following guidelines for medications such as dual antiplatelet and GP IIbIIIa in acute settings. He also mentioned possible causes to be presented such as dissection, side branch occlusion, collaterals and embolization. To conclude, he stated that patient selection and the risk related to the procedure have to be taken into account to avoid increased biomarkers and prevent necrosis during PCI.




The clinical relevance of myocardial necrosis during percutaneous coronary intervention

Notes to editor

This congress report accompanies a presentation given at the ESC Congress 2008. Written by the author himself/herself, this report does not necessarily reflect the opinion of the European Society of Cardiology.

The content of this article reflects the personal opinion of the author/s and is not necessarily the official position of the European Society of Cardiology.