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Young Investigator Award

Travel, best oral and best poster awards are given at the Working Group Annual Meeting.

Learn more

Cardiovascular Development Meeting 2017

The Official Meeting of the ESC Working Group on Development, Anatomy and Pathology

Add to calendar28/09/201714:00 30/09/201715:00 Europe/Paris Cardiovascular Development Meeting 2017
The goal of this annual meeting is to present the latest scientific research into the mechanisms of cardiovascular malformation, both congenital heart disease and adult-onset cardiovascular disease, in the fields of genomics, developmental genetics, anatomy and pathology.
Working Group on Development, Anatomy & Pathology contact@escardio.org DD/MM/YYYY
Genomics
Cardiovascular Anatomy & Development
Pathophysiology of the Cardiovascular System
In-person
event

Summary

The goal of this annual meeting is to present the latest scientific research into the mechanisms of cardiovascular malformation, both congenital heart disease and adult-onset cardiovascular disease, in the fields of genomics, developmental genetics, anatomy and pathology.

Focus on

Transcriptional regulation
Genetics and congenital heart defects 
Hands-on session on congenital heart disease
Endothelium and endocardium 
Cardiac lineages and progenitor populations
Cardiac growth and regeneration
Cardiovascular genetics and transcriptional regulation
Cardiomyopathy
Cilia and growth factor signalling 
Anatomy and Pathology
Hands-on session on adult onset cardiovascular disease



Meeting organiser

The meeting organisers are Dr. Marina Campione and Prof. Cristina Basso, University of Padova.

Meeting venue

The 2017 meeting of the Working Group on Development, Anatomy and Pathology will be held in Padua, Northern Italy.

pano_padova.jpg

 

Padua is one of the oldest Universities in the world (founded in 1222). Its botanical gardens are an UNESCO World Heritage Site and the Giotto frescos in Scrovegni Chapel are very special indeed.  The scientific program and history of Padua, coupled with modern Italian hospitality and style makes this a meeting not to be missed.

Abstract submissions - now closed

All abstracts will be accepted for poster presentations and the organizing committee will select abstracts for oral presentation in each session

Young Investigator Awards

Pexieder Award 

The Working Group will award the Pexieder prize for the best oral presentation during the meeting.

This award had been named in tribute to Tomas Pexieder, founder and first Co-Chairman of the Working Group on Development Anatomy and Pathology, formerly named "Embryology and Teratology".

Poster Awards

All submitted abstracts will be automatically entered for these prizes.

Travel Awards - now closed

The Padua Meeting will award travelling expenses up to five PhD-students and/or Junior Post-Docs (within 3 years after their PhD).

Applicant must be registered member of the Working Group (if not member yet, you can still join for free now)

Reimbursement is processed after the meeting and awardees may claim travel expenses via the ESC website with a maximum cash prize of 400 Euro. In the case of a no-show or lack of data presented at the meeting, the travel expense claim will not be processed.

Programme

Download the PDF

Thursday 28 September

Main University building "Palazzo del Bo"
2 via VIII Febbraio, 35122 Padova
Lecture Hall, Great Hall, "Aula Magna"

13:00-14:00: Registration

14:00-14:15: Welcome address by the local organisers - Cristina Basso

Session 1 : Genetics of human congenital heart defects

Chairs: Deborah Henderson, Marc-Philip Hitz

14:15-14:45: Lecture: Genetics of Congenital Heart Diseases: clinical implications - Bruno Marino

Abstracts:

14:45-15:00: Cardiac microstructure analysis by high-resolution synchrotron X-Ray Phase-Contrast Imaging of complex congenital heart disease in a human fetus - Patricia Garcia-Canadilla

15:00-15:15: Deciphering the Mechanisms of Developmental Disorders (DMDD): a powerful new resource for studying congenital heart disease (CHD) - Dorota Szmuska

15:15-15:30: Critical role of Phosphodiesterase 2A in congenital heart defects - Maria Rita Assenza

15:30-15:45: Exome Sequencing and Crispr-Cas9 Modelling of Left Ventricular Non-Compaction - Marcos Siguero-Alvarez

15:45-16:15: Coffee break

Session 2: Adult cardiomyopathy

Chair: Jose Maria Pérez-Pomares, Kalliopi Pilichou 

16:15-16:45: Lecture: Animal models on inherited cardiomyopathies - Jeffrey Saffitz, Boston-USA

Abstracts:

16:45-17:00: Characterization of a zebrafish AC8 model for the identification of early pathogenetic events and new therapeutic targets - Giorgia Beffagna

17:00-17:15: Whole-exome sequencing identifies mutations in TJP1 gene associated with arrhythmogenic cardiomyopathy - Alessandra Rampazzo

17:15-17:30: Genetic testing in Arrhythmogenic Cardiomyopathy: new insights into the disease determinants and new doubts - Elisabetta Lazzarini

17:30-17:45: Myocardial loss of Hand1 in the developing heart results in survivable morphological defect that end in diastolic heart failure - Antony Firulli

18:00Opening Lecture: Cardiovascular Pathology in the Land of the Doges: from morphology to DNA - Gaetano Thiene, introduced by Rosario Rizzuto, Rector Magnificus University of Padua

19:00-19:30: Free guided tour of the old University: Anatomical Theater, Hall of 40, Galileo Chair (Fabio Zampieri and Alberto Zanatta)

Evening reception

19:45-22:00: dinner buffet

Caffe Pedrocchi - Sala Rossini
15 Via VIII Febbraio

Friday 29 September

Institute of Pathological Anatomy, University of Padua Medical School
61 Via A. Gabelli, 35121 Padova
Anfiteatro G.B. Morgagni (Morgagni Hall)

08:15-08:30: poster setup

Session 3: signaling in cardiac developement

Chair: Maurice van den Hoff, Martina Brueckner 

08:30-09:00: Lecture: Imaging cardiomyocyte cell behavior during development - Didier Stainier

Abstracts:

09:00-09:15: Neuregulin-1 regulates cardiomyocyte polarity and oriented cell division during trabeculation - Paula Gómez-Apiñániz

09:15-09:30: COUP-TFII expression defines two different septum transversum cell compartments crucial to cardiac septation and compact ventricular wall growth - Jose Maria Perez-Pomarez

09:30-09:45: CCBE1 Is Required for the Development of the Sinus Venosus-Derived Coronary Vasculature - Josè Belo

09:45-10:00: Functional analysis of a novel causative gene for congenital heart defects - Srinivasan Sakthivel

10:00-10:30: Coffee break and poster viewing

Session 4:Cardiac growth ans regeneration

Chairs: Didier Stainier, Mélanie Philipp

10:30-11:00: Lecture: Biotechnological Drugs for Cardiac Repair and Regeneration - Mauro Giacca

Abstracts:

11:00-11:15: Analysis of underlying molecular mechanisms of neonatal cardiac regeneration - Fatih Kocabas

11:15-11:30: Zebrafish can fully regenerate the heart by quantitative restoration of cardiomyocyte number - Alberto Bertozzi

11:30-11:45: Experimental studies on miR-130 and miR-133 roles in atrial chamber specification during early cardiac looping - Carmen Lopez-Sanchez

11:45-12:30: Live video demonstration 1 :TGA and truncus arteriosus - S. Yen Ho, Carla Frescura

12:30-14:00: lunch and odd posters presentation

Session 5: Genetic interactions in cardiac development_1

Chairs: Mauro Giacca,  David Brook

14:00-14:30: Genetic architecture of congenital heart defects - Marc Hitz

Abstracts:

14:30-14:45: Investigation of the role of T-box genes in patterning the Second Heart Field - Magali Theveniau-Ruissy

14:45-15:00: Investigating a potential Tbx1-Pax9-Gbx2 genetic network in the control of cardiovascular development - Catherine Stothard

15:00-15:15: Vitamin B12 and SHF-dependent heart defects  in Tbx1 mutant mice - Gabriella Lania

15:15-15:45: Coffee break and poster viewing

Session 6: Genetic interactions in cardiac development_2

Chair: Thomas Brand, David Sedmera

Abstracts:

15:45-16:00: Tbx1 Interacts Genetically with Vegfr3 to Regulate Lymphangiogenesis in mice - Elizabeth Illingworth

16:00-16:15: Regulation of Follistatin-like 1 expression - Andrea Mattiotti

16:15-16:30: Tbx1-driven enhancer programming during cardiovascular development - Andrea Cirino

16:30-17:00: General Assembly

17:30-18:15: Keynote lecture: YAP/TAZ in stem cells and tissue regeneration - Stefano  Piccolo, introduced by Marina Campione

Free evening

Saturday 30 September

Institute of Pathological Anatomy, University of Padua Medical School
61 Via A. Gabelli, 35121 Padova
Anfiteatro G.B. Morgagni (Morgagni Hall)

Session 7: Cardiac conduction, innervation and metabolism

Chairs: Diego Franco,  Stefania Rizzo

Abstracts:

08:30-08:45: Conduction through developing reptilian hearts - David Sedmera

08:45-09:00: Mitochondrial density and function is similar in trabeculated and compact ventricular myocardium in healthy and noncompacted hearts - Bjarke Jensen

09:00-09:15: Bi- and three-dimensional characterization of the sympathetic innervation patterning in the human healthy myocardium - Anna Di Bona

09:15-09:30: His-Purkinje system hypoplasia induced by Nkx2-5 deletion leads to progressive conduction defects and heart failure - Lucile Miquerol

09:30-10:15: Live video demonstration 2: Cardiomyopathies (transplant and sudden death) - Annalisa  Angelini, Allard C van der Wal

10:15-11:00:  Coffee break and poster viewing

Session 8: Genetic approaches to cardiac valve disease

Chairs: Bill Chaudhry, Gaetano Thiene

Abstracts

11:00-11:15: Meis transcription factors in cardiac valve development and function - Maria Ester de la Cruz Crespillo

11:15-11:30: Deletion of Follistatin-like 1 from the endocardial/endothelial lineage causes mitral valve disease - Maurice van den Hoff

11:30-11:45: Investigating the role of LIM-only protein FHL2 during vascular calcification in bicuspid aortic valve disease - Vera van de Pol

11:45-13:15: Lunch and even posters presentation

Session 9: cilia, flow and left right signalling

Chair: Antonio Baldini, Marina Campione 

13:15-13:45: Cilia guide the heart: a journey from developmental mechanism to human genetics - Martina Brueckner

13:45-14:00: miR-103/107 regulates left-right asymmetry in zebrafish by modulating Kupffer's vesicle development and ciliogenesis - Jana Heigwer

14:00-14:15: Cilia control mural cells recruitment in vertebrates - Massimo Santoro

14:15-14:30: A predictive model of heart looping dynamics from 3D reconstructions in the mouse embryo - Sigolène Meilhac

14:30-15:00: Prizes and closing remarks

15:00: Free bus to Venice airport

For participants who are willing to stay more, some extra activities are organised

15:30-17:00: Free time activity: Guided visit to Padua  Botanical Garden (Unesco Heritage);(Alberto Zanatta)

Registration closed

Open from 15 May to 24 September 2017

Early fee: 15 May - 31 July

  • Standard: 330 Euros
  • Student: 230 Euros

Standard fee: 1 August - 24 September

  • Standard: 380 Euros
  • Student: 280 Euros

Members fee: 15 May - 24 September 2017

  • Working Group Member: 300 Euros
  • Nucleus Member: 150 Euros

Useful information

Where to fly

How to reach Padua from the Airport

Provided by Air Service, door to door service, need to be booked in advance
45’ drive

Take Busitalia from Airport to Padova Autostazione (adjacent to the Railway Station)
1h10’ drive

Venice-Padua schedule

Treviso-Padua schedule

Then, taxis are available at Padua Railway Station to reach the meeting venue

Note: A shuttle bus to VCE airport will be available at the end of the meeting (15:00).  
Detailed information will follow.

Meeting venue map

Download

Hotel Accommodations

Several mid-low budget hotels are available in the surroundings of the meeting venue, here below some links:

 

Working Group homepage