Our mission is to become a worldwide reference for education in the field for all professionals involved in the process to disseminate knowledge & skills of Acute Cardiovascular Care.
Our mission is to promote excellence in clinical diagnosis, research, technical development, and education in cardiovascular imaging in Europe.
Our mission is to promote excellence in research, practice, education and policy in cardiovascular health, primary and secondary prevention.
Our mission is to reduce the burden of cardiovascular disease in Europe through percutaneous cardiovascular interventions.
Our mission is to improve the quality of life of the population by reducing the impact of cardiac rhythm disturbances and reduce sudden cardiac death.
Our mission is to improve quality of life and longevity, through better prevention, diagnosis and treatment of heart failure, including the establishment of networks for its management, education and research.
The ESC Working Groups' goal is to stimulate and disseminate scientific knowledge in different fields of cardiology.
The ESC Councils' goal is to share knowledge among medical professionals practising in specific cardiology domains.
OUR MISSION: TO REDUCE THE BURDEN OF CARDIOVASCULAR DISEASE
Dr. Stefan Agewall,
In this session Dr Kastelein, Dr Barter, Dr Nicholls and Dr Ruschitzka discussed the future of treatment of low HDL cholesterol. The room was crowded so obviously the topic was interesting for the audience of the congress. There are large numbers of epidemiological studies that have identified HDL cholesterol as a strong, independent, inverse predictor of risk of coronary heart disease. There are several possible mechanisms but we really do not know how this potential protective effect is mediated. Evidence that raising HDL cholesterol will reduce cardiovascular adverse outcomes remains controversial. Obviously, treatment with torcetrapib is harmful, with an increased rate of cardiovascular events despite an increased HDL level. The reason for this failure is not completely understood. Torcetrapib increased blood pressure in the Illuminate study but this was not enough to explain the poor outcome in the torcetrapib group. The speakers discussed whether HDL treatment is a dead-end now, but all of them had some optimism about the future with different drug suggestions that may be effective not only in raising HDL cholesterol but also in decreasing cardiovascular events. Certainly, we need studies with hard end-points comparing statin treatment vs combination therapy (statin + a drug that raises HDL cholesterol). There are such studies ongoing but we will have to wait some years before we can achieve those results. Until then, we do not know if treatment of low HDL cholesterol is a pot of gold or Pandora’s box.
High-density lipoprotein: pot of gold or box of Pandora?
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