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28 November 2005

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Polyphenolic compounds from red grapes acutely improve endothelial function in patients with coronary heart disease

Authors:

For research paper contact:
Anna Norman
Marketing Manager, Lippincott Williams & Wilkins
Tel: +44 (0)20 7981 0615
Email: anorman@lww.co.uk 

For author comment contact:
Loukianos Rallidis, author
University General Hospital, Attikon, Greece
Email: rallidis@ath.forthnet.gr

ESC Press and PR Office
(for independent comment):
Gina Dellios
Tel: +33 (0)4 92 94 86 27
Fax: +33 (0)4 92 94 86 72
Email: gdellios@escardio.org

 

Polyphenols obtained from red grapes improved flow-mediated dilation (FMD) acutely in men with documented coronary artery disease reports a recent European Journal of Cardiovascular Prevention and Rehabilitation (EJCPR) article.

Although it has been known for some time that moderate consumption of red wine improves endothelial-dependent vasodilatation, until now, it has not been clear which constituents are responsible for this effect. “This study confirms that the consumption of a red grape extract with polyphenols being the only active components, results in improved FMD,” says Loukianos Rallidis, Second Department of Cardiology, University General Hospital, Attikon.

The red grape polyphenol extract (RGPE) given to each subject in the study, was derived from 1kg of red grapes – more that would ordinarily be consumed in the usual dietary intake of grapes. It is interesting to consider the future production of polyphenol supplements derived from red grapes if long-term studies confirm the beneficial effects found in this initial research.

Reference:

Notes to editors:

EJCPR, www.ejcpr.com, is the Official Journal of the European Association for Cardiovascular Prevention and Rehabilitation, a Registered Branch of the European Society of Cardiology. Please acknowledge the journal as a source in any articles. A copy of the paper is available on request.

This journal, embraces all the scientific, clinical and public health disciplines that address the causes and prevention of cardiovascular disease, as well as cardiovascular rehabilitation and exercise physiology.

 
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