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Effective control of paroxismal atrial fibrillation: the big challenge

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Presentation title: Effective control of paroxismal atrial fibrillation: the big challenge
Author(s): Blomström-Lundqvist C. (Uppsala, SE)
Date: 29 August 2004
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Effective control of paroxysmal atrial fibrillation - the big challenge
Patterns of AF

Prevalence of Diagnosed AF Stratified by Age and Sex


AF demographics
AF: Non-cardiac causes
Autonomic AF

‘Lone’ AF
Approach to AF management
Stroke in AF; Paroxysmal vs Chronic

Stroke Rate in AF Effect of Risk factors and Age.
Approach to AF management

Pharmacological management.
Pharmacological management.
Antiarrhythmic drug therapy.

Antiarrhythmic drug therapy.
Sotalol
Class IC drugs

Amiodarone in AF
Amiodarone
Amiodarone monitoring

Dofetilide: Probability of Maintaining SR
Dofetilide - Neutral effect on mortality
Approach to AF management

Recommendations to control heart rate –AV nodal blocking agents (oral adm.)
Cumulative Mortality.

Result
Conclusions made in AFFIRM study
PAF: Non-pharmacological Rx

Clinical outcome after AVN ablation and pacing therapy for AF
After AVN ablation
Survival after AVN ablation worse for pats with a history of CHF vs Expected Survival among Age- and Sex-Matched Controls.

Recommendations for Heart Rate Control in Patients with AF
Mapping-guided RF ablation of PV
Circumferential RF PV Ablation

Mortality, morbidity, and QoL - circumferential PV ablation for AF
Catheter ablation LA/PV
Conclusions


Recommendations for Pharmacological Therapy to Maintain Sinus Rhythm
Recommendations for Pharmacological Therapy to Maintain Sinus Rhythm

AFFIRM: % Sinus Rhythm at Follow-up
 
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