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A "heart failure profile" of serum and plasma markers?

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Presentation title: A "heart failure profile" of serum and plasma markers?
Author(s): M. Cowie (London, GB)
Date: 31 August 2003
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Data for the clinician
‘Conventional’ blood tests

Blood ‘biomarkers’
What the laboratory wants
Candidates

Natriuretic peptides
BNP is raised in heart failure
BNP is raised in damaged hearts

The clinic setting
ROC curve for the natriuretic peptides
NPs as ‘rule out’ tests for HF comparing diagnostic value of NPs when negative predictive value is 98%

UK Natriuretic Peptide Study

Diagnostic utility

‘NPs in the Community’ Study Abstracts presented at ESC 2002
‘NPs in the Community’ Study ESC 2002
Diagnosis Patients in the Emergency Room



FREQUENCY HISTOGRAM

Clarification of Diagnosis by BNP
DECISION STATISTICS
Cautions!


Testing is now straightforward
Conclusions
 
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