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Importance of hypertension in the perimenopausal woman

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Presentation title: Importance of hypertension in the perimenopausal woman
Author(s): Preston R.
Date: 12 May 2006
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The Importance of Hypertension in Perimenopausal Women
Outline
2003 European Society of Hypertension-European Society of Cardiology (ESH-ESC) Guidelines for the Management of Arterial Hypertension

Hypertension: General Comments


Causes of Hypertension
Hypertension Prevalence in Men and Women
Benefits of Antihypertensive Therapy in Women versus No Treatment (N=40777)

Hypertension Awareness, Treatment, and Control: US 1976 to 2000
Hypertension Control (%) in European Nations
ESH-ESC Classification of BP Levels (mm Hg)

Impact of High-normal BP on CV Events in Women (Cumulative Incidence %)
An Increase of 20 mm Hg in SBP Doubles CV Risk (N=1,000,000; 61 studies)
Management of High-Normal Blood Pressure (130-139/85-89 mm Hg)

Trial of Hypertension Prevention (TROPHY)
Subjects with new-onset hypertension
Proposed Mechanisms for “Menopausal” Hypertension (Investigational)

Aldosterone, Hypertension and Vascular Injury
Drospirenone 3 mg/Estradiol 1 mg in High Risk Hypertensive Postmenopausal Women
Systolic BP (mm Hg) versus Time (Days) (N=230)

DRSP/E2 has an additive effect on BP when given along with antihypertensive drugs
Summary/Conclusions
 
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