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Third Universal Definition of Myocardial Infarction

ESC Clinical Practice Guidelines

Topics: Myocardial Disease


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25/08/2012 00:00:00

Current versions available to download

Publication dateVersionsReferencesSize
2012Full TextEuropean Heart Journal (2012) 33, 2551–2567
2012Pocket Guidelines
2012PdaUniv. Def of MI App
2012 Slide-set31 educational slides4 MB
2012CME Questions1 hour of External CME credits

Current translated versions available to download:


Chairpersons: Kristian Thygesen, Joseph S. Alpert, Harvey D. White  -
Biomarker Subcommittee: Allan S. Jaffe, Hugo A. Katus, Fred S. Apple, David  A. Morrow - ECG Subcommittee: Bernard Chaitman, Peter M. Clemmensen, Per Johanson, Hanoch Hod - Imaging Subcommittee: S. Richard Underwood, Jeroen J. Bax, Robert Bonow, Fausto Pinto, Raymond J. Gibbons - Classification Subcommittee: keith A. Fox, Dan Atar, L. Kristin Newby, Marcello Galvani, Chrsitian W. Hamm - Intervention Subcommittee: Barry F. Uretsky, Philippe G. Steg, William Wijns, Jean-Pierre Bassand, Phillippe Menasche, Jan Ravklide
Trials & Registries Subcommittee: E. Magnus Ohman, Elliot M. Antman, Lars C. Wallentin, Paul W. Armstrong, Maarten L. Simoons -  Heart Failure Subcommittee: James L. Januzzi, Markku S. Nieminen, Mihai Gheorghiade, Gerasimos Filippatos - Epidemiology Subcommittee: Russell V. Luepker, Stephen P. Fortmann, Wayne D. Rosamond, Dan Levy, David Wood - Global Perspective Subcommittee: Sidney C. Smith, Dayi Hu, José-Luuis Lopez-Sendon, Roe Marie Roberston, Douglas Weaver, Michal Tendera, Alfred A. Bove, Alexander N. Parkomenko, Elena J. Vasilieva, Shandi Mendis

Declarations of Interest of the experts involved in the elaboration of the document.

Endorsed by:

Table of Contents

  • Definition of myocardial
  • infractionIntroductionPathological
  • characteristics of myocardial ischaemia and infarctionBiomarker detection of myocardial injury with necrosis
  • Clinical features of myocardial ischaemia and infarction
  • Clinical classification of myocardial infarction
    Spontaneous myocardial infarction (MI type 1)
    Myocardial infarction secondary to an ischaemic imbalance (MI type 2)
    Cardiac death due to myocardial infarction (MI type 3)
    Myocardial infarction associated with revascularization procedures (MI types 4 and 5)
  • Electrocardiographic detection of myocardial infarction
  • Prior myocardial infarction
  • Silent myocardial infarction
  • Conditions that confound the ECG diagnosis of myocardial infarction
  • Imaging techniques
    Radionuclide imaging
    Magnetic resonance imaging
    Computed tomography
    Applying imaging in acute myocardial infarction
    Applying imaging in late presentation of myocardial infarction
  • Diagnostic criteria for myocardial infarction with PCI (MI type 4)
  • Diagnostic criteria for myocardial infarction with CABG (MI type 5)
  • Assessment of MI in patients undergoing other cardiac procedures
  • Myocardial infarction associated with non-cardiac procedures
  • Myocardial infarction in the intensive care unit
  • Recurrent myocardial infarction
  • Reinfarction
  • Myocardial injury or infarction associated with heart failure
  • Application of MI in clinical trials and quality assurance programmes
  • Public policy implications of the adjustment of the MI definition
  • Global perspectives of the definition of myocardial infarction

Previous versions

YearJournalIssuePagesFull Text
2007Eur Heart J282525-2538
2000Eur heart J211502-1513