Cardiomyopathies are a heterogeneous group of disorders characterised by structural and functional abnormalities of the myocardium. Individually, these disorders are relatively uncommon, but collectively they have an estimated prevalence within the European population of 3 per 1000 individuals. All cardiomyopathies cause premature death from arrhythmia and progressive heart failure and represent a substantial burden to the healthcare services of all European nations.
The aim of the EORP registry is to collect previously unobtainable data on the epidemiology and outcomes of patients seen across a range of centres in Europe in order to improve clinical service provision and therapy. To date, most information about the presentation and natural history of individual disorders comes from cohort studies in a few centres in Europe and the United States.
In addition to data collected on the major types of cardiomyopathies, the Long-Term phase will also observe patients with myocarditis, an inflammatory disease of the heart in which there is histological evidence of inflammatory infiltrates within the myocardium associated with myocyte degeneration and necrosis of non-ischaemic origin.
Finally, following consultation with the ESC Working Group on Myocardial and Pericardial Disease and the Association for European Paediatric and Congenital Cardiology Working Group on Genetics and Basic Science (AEPC WG), the protocol allows enrolment of paediatric and young patients.