Course Objectives:
- Inspire a new generation of basic cardiovascular science leaders taken from among the most gifted science and medical graduates
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- Provide opportunities to meet face-to-face role models from an expert faculty of successful cardiovascular scientists
- Give examples of how cardiovascular science has advanced in key areas and has impacted on clinical practice
- Identify major challenges for the next generation
- Impart insights into those theoretical aspects of pathophysiology, pharmacology, molecular biology and genomics of cardiac and vascular diseases necessary to underpin a selection of future challenges
- Encourage thinking on the social issues (e.g. gender, deprivation) that hinder health in the European population
- Open up a broader perspective on the issues necessary for implementation of research findings in medical practice
- Increase confidence among young scientists as investigators and communicators
- Promote networking between young scientists throughout Europe
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Target audience:
Mainly early stage researchers (PhD and MD/PhD students in the first three years of their research) plus a few more experienced researchers whose PhD degree was obtained within the last 2 years.
Course Directors:
A C Newby (UK); J-L Balligand (BE)
Scientific Programme
Sunday 12th June
17.00 Poster hanging up and viewing
18.00 Welcome from JL Balligand and A Newby
18.15 Opening keynote plenary lecture: The endothelial saga: regenerate to get old - P Vanhoutte (HK)
Monday 13th June
9.00 Session I A ‘Inflammation in Cardiac and Vascular Biology’
Inflammation and atherosclerosis – G Hansson (SE)
Inflammation in Heart Failure – D Hilfiker-Kleiner (DE)
Inflammation and extracellular proteases – A Newby (UK)
11.30 Session II A ‘Therapeutic angiogenesis’
Oxygen sensing and arteriogenesis / angiogenesis – M Mazzone (BE)
Post-ischaemic angiogenesis: basic concept and new treatment options - C Emanueli (UK)
and Session IIB ‘Ischaemia and reperfusion’
Basic concepts - H Post (AT)
Signalling in cardiomyocyte hypertrophy - L de Windt (NL)
Control of fibrosis by miRNA: in vivo applications - T Thum (DE)
14.00 Breakout session I
Writing and reviewing grant proposals - A Newby (UK) and G Hansson (SE)
Writing and reviewing a paper - D Garcia Dorado (SP) and J-L Balligand (BE)
Gender - D Hilfiker-Kleiner (DE), V Regitz-Zagrosek (DE)
Translation – P Vanhoutte (HK)
16.00 Plenary Poster Session
Tuesday 14th June
9.00 Plenary Session IV ‘Oxidant stress’
Basic Concepts – J Dulak (PL)
Endothelial mechanisms– J-L Balligand (BE)
Consequences for Ischaemia Reperfusion – R Schulz (DE)
11.30 Session VA ‘Vulnerable plaque – pathogenesis, imaging and treatment’
Pathogenesis – A Newby (UK)
Imaging and drug treatment – G Hansson (SE)
Immunomodulation – G Hansson (SE)
And Session VB ‘Myocardial remodeling’
Basic concepts- D Garcia Dorado (SP)
Chronic ischemia and ischemic cardiomyopathy - K Sipido (BE)
Pharmacologic treatment options - R Schulz (DE)
14.30 Break-out Sessions
Proteomics – A Horrevoets (NL)
Micro RNAs - L De Windt (NL)
In vivo haemodynamics - H Post (AT)
Wednesday, 15th June
9.00 Plenary Session VI ‘Stem Cells’
Heart Development - R Kelly (FR)
Biology of perivascular progenitor cells – P Madeddu (UK)
Cardiac Stem Cells – J Sluijter (NL)
11.30 Session VII A ‘Atherothrombosis’
Basic Concepts – T Padro (SP)
Endothelial integrity - A Horrevoets (NL)
Microparticles – F Dignat-George (FR)
And Session VII B – Heart Failure and Arrythmogenesis
Calcium and the control of cardiac contraction - D Eisner (UK)
Ca2+ dependent arrhythmias - S Richard (FR)
Treatment in women and men – V Regitz-Zagrosek (DE)
17.00 Breakout Session III
Genomics – A Horrevoets (NL)
Vascular gene therapy – A Baker (UK)
Flurescence Confocal Microscopy - S Richard (FR)
Thursday 16th June
9.00 Free Communications – The Organisers’ Choice
Judges F Dignat-George (FR), AC Newby (UK); JL Balligand (BE)
11.30 Plenary session XI
‘A Clinical Perspective on Basic Science’ - V Regitz-Zagrosek (DE)
Poster and oral communication awards