April 2012
New Oral Anticoagulants in Atrial Fibrillation and Acute Coronary Syndromes: a position paper from the ESC Working Group on Thrombosis—Task Force on Anticoagulants in Heart Disease
Coordinating Committee: Raffaele De Caterina, Steen Husted, Lars Wallentin
Task Force Members: Raffaele De Caterina, Steen Husted, Lars Wallentin, Felicita Andreotti, Harald Arnesen, Fedor Bachmann, Colin Baigent, Kurt Huber, Jørgen Jespersen, Steen Dalby Kristensen, Gregory Y. H. Lip,João Morais, Lars Hvilsted Rasmussen, Agneta Siegbahn, Freek W. A. Verheugt, Jeffrey I. Weitz
Journal: Journal of the American College of Cardiology
Issue: Vol. 59, No. 16, 2012
doi:10.1016/j.jacc.2012.02.008
Until recently, vitamin K antagonists were the only available oral anticoagulants, but with numerous limitations
that prompted the introduction of new oral anticoagulants targeting the single coagulation enzymes thrombin
(dabigatran) or factor Xa (apixaban, rivaroxaban, and edoxaban) and given in fixed doses without coagulation
monitoring. Here we review the pharmacology and the results of clinical trials with these new agents in stroke
prevention in atrial fibrillation and secondary prevention after acute coronary syndromes, providing perspectives
on their future incorporation into clinical practice.
January 2012
EuroThrombosis: annual meeting of the European Society of Cardiology Working Group on Thrombosis
Authors: Giulio Coluzzi, Eliano Pio Navarese and Felicita Andreotti
Journal: Expert review of hematology
Issue: Expert Rev. Hematol. 5(1), 39–42 (2012)
EuroThrombosis Summit
Oporto, Portugal, 7–8 October 2011
EuroThrombosis is the annual meeting of the European Society of Cardiology Working Group on Thrombosis. It gathers clinicians and scientists interested in clinical/experimental thrombosis.
The 2011 congress was held in Oporto, Portugal, and presented an appealing program with state-of-the-art sessions on new antiplatelet/anticoagulant agents, diabetes, cellular mechanisms of thrombosis and miRNAs.
December 2011
Bleeding risk assessment and management in atrial fibrillation patients
Executive Summary of a Position Document from the European Heart Rhythm Association (EHRA), endorsed by the European Society of Cardiology (ESC) Working Group on Thrombosis
Authors: G. Y. H. Lip, F. Andreotti, L. Fauchier, K. Huber, E. Hylek, E. Knight, D. Lane, M. Levi, F. Marín, G. Palareti, P. Kirchhof
Journal: Thrombosis and Haemostasis
ISSN: 0340-6245
DOI: http://dx.doi.org/10.1160/TH11-10-0690
Issue: 2011: 106/6 (Dec) pp. 993-1234
Pages: 997-1011
- Read the press release related to this position paper:
European experts issue position document on bleeding risk assessment and management in atrial fibrillation patients
In the December 2011 issue of Thrombosis and Haemostasis, an important position document from the European Heart Rhythm Association [EHRA] and the European Society of Cardiology [ESC] Working Group on Thrombosis on bleeding risk assessment and management in atrial fibrillation patients is published.
June 2011
Bleeding in acute coronary syndromes and percutaneous coronary interventions: position paper of the Working Group Thrombosis of the ESC
Authors: Philippe Gabriel Steg (France), Kurt Huber (Austria), Felicita Andreotti (Italy), Harald Arnesen (Norway), Dan Atar (Norway), Lina Badimon (Spain), Jean-Pierre Bassand (France), Raffaele De Caterina (Italy), John A. Eikelboom (Canada), Dietrich Gulba (Germany), Martial Hamon (France), Ge´rard Helft (France), Keith A.A. Fox (UK), Steen D. Kristensen (Denmark), Sunil V. Rao (USA), Freek W. A. Verheugt (Netherlands), Petr Widimsky (Czech Republic), Uwe Zeymer (Germany), and Jean-Philippe Collet (France)
European Heart Journal- 2011:
DOI: 10.1093/eurheartj/ehr204
First Published on line: 29 June 2011
- Read the press release related to this position paper:
ESC calls for greater awareness of potential for adverse events from bleeding as a result of PCI
The position paper, published online today in The European Heart Journal, summarises current knowledge regarding the epidemiology of bleeding in ACS and PCI, and provides a European perspective on management strategies to minimise the extent of bleeding and subsequent adverse consequences.
May 2011
Peri-operative management of antiplatelet therapy in patients with coronary artery disease
Joint position paper by members of the working group on Perioperative Haemostasis of the Society on Thrombosis and Haemostasis Research (GTH), the working group on Perioperative Coagulation of the Austrian Society for Anesthesiology, Resuscitation and Intensive Care (ÖGARI) and the Working Group Thrombosis of the ESC
Authors: W. Korte, M. Cattaneo, P.-G. Chassot, S. Eichinger, C. von Heymann, N. Hofmann, H. Rickli, M. Spannagl, B. Ziegler, F. Verheugt, K. Huber
Thrombosis and Haemostasis - 2011: 105/5(May) pp. 743-932
DOI: 10.1160/TH10-04-0217
January 2009, Special Article
Interindividual variability in the response to oral antiplatelet drugs
A position paper of the Working Group on antiplatelet drugs resistance appointed by the Section of Cardiovascular Interventions of the Polish Cardiac Society, endorsed by the Working Group on Thrombosis of the European Society of Cardiology
Authors: Wiktor Kuliczkowski, Adam Witkowski, Lech Polonski, Cezary Watala,
Krzysztof Filipiak, Andrzej Budaj, Jacek Golanski, Dariusz Sitkiewicz,
Jerzy Pregowski, Jacek Gorski, Marian Zembala, Grzegorz Opolski, Kurt Huber,Harald Arnesen, Steen D. Kristensen, and Raffaele De Caterina
April 2007
ESC Position paper on Anticoagulants in heart disease: current status and perspectives
by Raffaele De Caterina; Steen Husted; Lars Wallentin; Giancarlo Agnelli; Fedor Bachmann; Colin Baigent; Jorgen Jespersen; Steen Dalby Kristensen; Gilles Montalescot; Agneta Siegbahn; Freek W.A. Verheugt; Jeffrey Weitz
October 2005, Special article
Pre-hospital reperfusion therapy: a strategy to improve therapeutic outcome in patients with ST-elevation myocardial infarction
by Kurt Huber, Raffaele De Caterina, Steen D. Kristensen, Freek W.A. Verheugt, Gilles Montalescot, Lina Badimon Maestro, Frans Van de Werf for the Task Force on Pre-hospital Reperfusion Therapy of the Working Group on Thrombosis of the ESC
Eur. Heart J., October 2005; 26: 2063 - 2074.
Consensus Documents
October 2009 - Consensus Document
Management of Antithrombotic Therapy in Atrial Fibrillation Patients Presenting With Acute Coronary Syndrome and/or Undergoing Percutaneous Coronary Intervention/ Stenting
Gregory Y. H. Lip; Kurt Huber; Felicita Andreotti; Harald Arnesen; K. Juhani Airaksinen; Thomas Cuisset; Paulus Kirchhof; Francisco Marín
Document Reviewers: A. Rubboli, A. J. Camm, H. Heidbuchel, E. Hoffmann, N. Reifart, F. Ribichini, F. Verheugt
2004
Expert Consensus Document on the Use of Antiplatelet Agents
The Task Force on the Use of Antiplatelet Agents in Patients with Atherosclerotic Cardiovascular Disease of the European Society of Cardiology: Carlo Patrono (Chairperson), Fedor Bachmann, Colin Baigent, Christopher Bode, Raffaele De Caterina, Bernard Charbonnier, Desmond Fitzgerald, Jack Hirsh, Steen Husted, Jan Kvasnicka, Gilles Montalescot, Luis Alberto Garcı´a Rodrı´guez, Freek Verheugt, Jozef Vermylen, Lars Wallentin
EHJ 2004;25:166-181
Philippe Gabriel Steg (France), Kurt Huber (Austria), Felicita Andreotti (Italy),Harald Arnesen (Norway), Dan Atar (Norway), Lina Badimon (Spain), Jean-Pierre Bassand (France), Raffaele De Caterina (Italy), John A. Eikelboom (Canada), Dietrich Gulba (Germany), Martial Hamon (France), Ge´rard Helft (France), Keith A.A. Fox (UK), Steen D. Kristensen (Denmark), Sunil V. Rao (USA), Freek W. A. Verheugt (Netherlands), Petr Widimsky (Czech Republic), Uwe Zeymer (Germany), and Jean-Philippe Collet (France)European Heart Journal- 2011: DOI: 10.1093/eurheartj/ehr204 First Published on line: 29 June 2011