"The heart and beyond: intercellular and interorgan communication"
A Joint meeting of Working Groups on Myocardial Function and Cellular Biology of the Heart.
The upcoming meeting is a joint meeting of the ESC Working Groups on Myocardial Function and Cellular Biology of the Heart. An exciting scientific programme, with outstanding invited speakers, in a beautiful setting of wonderful Villa Monastero, allowed scientific exchanges in a friendly, relaxed atmosphere.
ProgrammeThe scientific programme offers several types of sessions:
- abstracts presentations
- numbers of invited lectures from international speakers
Thursday 2 May11.00 – 16.00 ESC WG Nucleus Meetings
16.25 – 16.30 Welcome and opening remarks Denise Hilfiker-Kleiner (Germany)
Session I: Message in a bottle – Microvesicles and intercellular communication
Chairs: Peter Ferdinandy (Hungary) and Gianluigi Condorelli (Italy)
16.30 – 17.00 Microvesicles and exosomes in cardiovascular health and disease - Joost Sluijter (Netherlands)
17.00 – 17.30 MicroRNA and communication beyond the heart -Thomas Thum (Germany)
17.30 – 18.00 Exosomes: More than just biomarkers of cardiovascular disease - Sean Davidson (UK)
18.00 – 18.30 2 Oral abstract presentations:
- MicroRNA-212 is an anti-angiogenic miRNA - Kumarswamy Regalla (Germany)
- 16K prolactin-induced expression of miR-146a is a therapeutic target and a specific biomarker for peripartum cardiomyopathy - Melanie Ricke-Hoch (Germany)
19.30 Dinner (Villa Cipressi)
Friday 3 May
Session II: Regenerative therapy for the heart
Chairs: Felix Engel (Germany) and Stephane Heymans (Belgium)
09.00 – 09.30 Cardiomyocyte communication with its neighbours - Thomas Braun (Germany)
09.30 – 10.00 In vivo selection of siRNAs to keep cardiomyocyte regenerative potential in adulthood - Mauro Giacca (Italy)
10.00 – 10.30 Circadian rhythms in cardiac regeneration -Linda W. van Laake (Netherlands)
10.30 – 11.00 2 Oral abstract presentations :
- Impact of the transcription factor GATA2 in endothelial cells on pathological cardiac hypertrophy - Jörg Heinecke (Germany)
- Direct interaction between sympathetic neurons and cardiomyocytes forms a high-agonist concentration and diffusion-estricted signaling domain at ‘cardiac synapses’ - Marco Mongillo (Italy)
11.00 – 11.30 Coffee break (Villa Monastero)
Session III: Interorgan communication via the metabolic highway
Chairs: Rosalinda Madonna (Italy) and Jean-Luc Balligand (Belgium)
11.30 – 12.00 PGC1-α and the angiogenic balance as a switch in physiological vs pathophysiological adaptation of the heart -Zoltan Arany (USA)
12.00 – 12.30 Systemic effects of cancer on regulation and function of the cardiac sarcomere - Denise Hilfiker-Kleiner (Germany)
12.30 – 13.00 2 Oral abstract presentations :
- Nitric Oxide Synthase & AMP-Activated Protein Kinase Dependent Signaling Pathways are Involved in the Anti-Hypertrophic Effect of The Human Beta 3 Adrenoreceptor -Emilie Dubois-Deruy (Belgium)
- The hypoxia-inducible microRNA cluster miR-199a-214 cluster targets myocardial PPARβ/δ and impairs mitochondrial fatty acid oxidation - Hamid Azzouzi (Netherlands)
13:00 – 14:00 Lunch (Villa Cipressi)
Session IV: Moderated Poster session (I) guided by Leon De Windt (Netherlands) and Manuel Mayr (GB)
14.00 – 16.00 Poster session
16.00 – 16.30 Coffee break (Villa Monastero)
Session V: New insights into myocardial fibrosis
Chairs: Johann Bauersachs (Germany), Carlo Gabriele Tocchetti (Italy)
16.30 – 17.00 Endothelial cells undergo EMT to generate myofibroblasts upon stress - Elizabeth Zeisberg (Germany)
17.00 – 17.30 Lineage tracing reveals ADAM12+ pericytes as precursors of myofibroblasts - Lucie Peduto (France)
17.30 – 17.45 Oral abstract presentation :
Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction - Tatyana Novoyatleva (Germany)
17.45 – 18.00 Presentation by VisualSonics B.V.
19.30 Dinner (Villa Cipressi)
Saturday 4 MaySession VI: Mitochondria transfer in and out of the heartChairs: Sean Davidson (UK) and Angela Clerk (UK)
08.30 – 09.00 How to measure mitochondrial function - Marisol Ruiz-Meana (Spain)
09.00 – 09.30 Stem cell reprogramming of adult cardiomyocytes: cell fusion and mitochondria transfer - Anne-Marie Rodriguez (France)
09.30 – 10.00 Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure - Kinya Otsu (London)
10.00 – 10.30 2 Oral abstract presentations :
- Oxidative/nitrosative stress in hypercholesterolemic hearts: the role of microRNA-25 regulated NADPH oxidase 4 - Zolta Varga (Hungary)
- Immune modulation by regulatory T cells preserves cardiac function and promotes cardiomyocyte proliferation after myocardial infarction - Serena Zacchigna (Italy)
Session VII: Moderated Poster session (II) guided by Sean Davidson (UK) and Felix Engel (Germany)
11.00 – 13.00 Poster session
13.00 –14.00 Lunch (Villa Cipressi)
Sunday 5 MaySession VIII: Protecting the heart at a distanceChairs: Rainer Schulz (Germany) and Derek Hausenloy (UK)
09.00 – 09.30 Mechanisms underlying remote ischemic conditioning - Andrew Redington (Canada)
09.30 – 10.00 Optogenetic control of heart muscle in vitro and in vivo - Philipp Sasse (Germany)
10.00 – 10.30 Extracellular RNA and myocardial protection - Klaus Preissner (Germany)
10.30 – 10.45 Oral abstract presentation :
Paracrine factors from cardiac fibroblasts protect cardiomyocytes against ischemia-reperfusion injury - Maryline Abrial (France)10.45 – 11.00 Coffee break (Villa Monastero)
Session IX: Signaling cross-talk in myocardial remodeling
Chairs: Guido Tarone (Italy) and Ralph Knoell (London)
11.00 – 11.30 Multiple roles of AKAP-Lbc in cardiac remodeling - Dario Diviani (Switzerland)
11.30 – 12.00 PI3K/PKA signaling - Emilio Hirsch (Italy)
12.00 – 12.15 Oral abstract presentation :
Molecular Modulation of Post-Ischemic Cardiac Remodeling by Hindlimb Ischemia Gabriele Giacomo Schiattarella (Italy)
Session X: Translational session Chair: Denise Hilfiker-Kleiner (Germany)
12.15 – 13.00 Allosteric Effectors of Cardiac Myosin Function: Activators, Inhibitors, and Pharmacoperones - Dietmar Manstein (Germany)
13.00 Closing remarks and farewell - Derek Hausenloy (UK)
Upload the programme here!
The scientific program directors of the annual meeting of the ESC Working group on Myocardial Function and Cellular Biology of the Heart thank you for your abstract submission and for your interest.
Only one abstract per submitter has been accepted.
|Standard registration fee||200 € - Deadline : 15 March 2013|
|Late registration fee||250€ - Deadline : 22 April 2013|
NB: The registration fees are covering registration to the meeting, 3 nights of hotel accommodation (check in on 2 May ; Check out on 5 May h 2013) and meals (except Saturday night).
Only active participants (i.e. oral or abstract presenters or chair) will be able to attend the meeting.
Due to limited space scientists are expected to share rooms - for this we need information on gender and age. You may indicate colleagues with whom you prefer to share rooms. However, be infomed that we may have to arrange differently.
The organizing committee will coordinate the hotel booking for you and will allocate rooms. You will be notified by email about the location of your hotel in Varenna (2-5 May 2013).
Travel and City
How to reach Varenna:
- By plane: from the airports of Milano Linate and Milano Malpensa, there are special shuttle buses direct to Central Station, from where trains to Sondrio/Tirano - then follow the directions:
Please check the bus shuttle schedules from Milano/Malpensa to Milano Central Station
Please check the train schedules from Milano Central Station to Varenna
- By train: from Central Station, please take a train to Sondrio/Tirano
- By car: from Milano take the road to Lecco (SS 36), when arrival in Lecco follow the road along the lake (S. Prov. 72) and then exit at Abbadia Lariana /Mandello /Varenna - Villa Monastero is placed along the road to the country, where there is also a convenient parking lot.
- "Fly to Lake-Bus-Shuttle": There is also the possibility to use the "Fly to Lake-Bus-Shuttle" from Milano/Malpensa
The ESC Working Groups on Myocardial Function and Cellular Biology of the Heart wish to thank the support of their sponsors:
|VisualSonics Inc.|| |
|The Company of Biologists Ltd.|
Journal of Cell Science
The Journal of Experimental Biology
|Experimetria Ltd.|| |
|Abcam plc|| |
|IonOptix Ltd.|| |
|Wolters Kluwer|| |
|DBTA Italia|| |
|NanoSight Ltd.|| |